N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine

C18H35NO2

CAS118134-30-8
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
118134-30-8
UN Number
3082
Index Number
612-150-00-X
PubChem CID
86160

Physical-chemical properties

Molecular Formula
C18H35NO2
Molar Mass
297.50 g/mol
IUPAC Name
N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine

Chemical Identifiers

InChI
InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3
InChI Key
PUYXTUJWRLOUCW-UHFFFAOYSA-N

Overview

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine (CAS 118134-30-8) is a complex spirocyclic tertiary amine compound with distinctive molecular architecture and multiple safety classifications. This specialized chemical compound features a unique spirocyclic structure combining a 1,4-dioxane ring system with a cyclohexane framework, enhanced by a tert-butyl substituent and a tertiary amine functional group. With a molecular formula of C18H35NO2 and molecular weight of 297.5 g/mol, this substance represents an advanced example of synthetic organic chemistry applications in industrial processes. The compound's complex three-dimensional structure provides specific chemical properties that make it valuable for specialized technical applications. The safety profile of this compound requires careful handling protocols, as indicated by its multiple hazard classifications including reproductive toxicity category 2, acute toxicity category 4, and specific target organ toxicity. The presence of GHS08, GHS07, and GHS09 pictograms emphasizes the need for appropriate personal protective equipment and environmental precautions during handling and storage. Its classification under ADR class 9 indicates specific transport requirements for miscellaneous dangerous substances. Industrial applications typically involve its use as a specialized intermediate in pharmaceutical synthesis, agrochemical formulations, and advanced materials development. The compound's unique structural features make it particularly suitable for applications requiring specific stereochemical properties or selective binding characteristics. Unlike simpler amine compounds such as 6-amino-N-methylnaphthalene-2-sulfonamide, this spirocyclic structure offers enhanced stability and selectivity in chemical processes. OYSI maintains reliable supply chains for this specialized compound, ensuring consistent availability for European industrial customers requiring high-purity technical-grade materials.

Safety & Classification

Warning
Classification:

Repr. 2; Acute Tox. 4; Acute Tox. 4; Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Skin Sens. 1; Aquati...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3082
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameSpiroxamin (ISO)
Marine PollutantNo

Frequently Asked Questions

What is N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is an organic chemical compound with CAS number 118134-30-8 and molecular formula C18H35NO2. This tertiary amine features a complex spirocyclic structure with a tert-butyl substituent and has a molecular weight of 297.5 g/mol. The compound is classified as hazardous with multiple health and environmental concerns, requiring careful handling in industrial applications.

What are the physicochemical properties of N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine has a molecular weight of 297.5 g/mol and contains nitrogen and oxygen functional groups within its spirocyclic structure. As a tertiary amine compound, it likely exhibits basic properties and may have characteristic amine odor. The presence of the dioxaspiro ring system and tert-butyl group influences its solubility and volatility characteristics, though specific physical data should be confirmed from technical datasheets.

What is N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine used for?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is typically used as a chemical intermediate or specialty reagent in industrial synthesis processes. Its complex spirocyclic structure containing amine functionality makes it valuable for pharmaceutical research, fine chemical manufacturing, or as a building block in organic synthesis. The specific applications depend on the compound's reactivity profile and the requirements of downstream chemical processes.

How to handle N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine safely?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine requires careful handling due to its classification as Repr. 2, Acute Tox. 4, and skin irritant/sensitizer. Essential PPE includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume extraction to prevent inhalation. Avoid skin contact and ensure proper training on emergency procedures before handling this substance.

How to store N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine correctly?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers upright and properly labeled with hazard information. Storage areas should be equipped with appropriate spill containment and emergency equipment. Separate from oxidizing agents and other reactive chemicals to prevent unwanted reactions.

What to do in case of contact with N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

Skin contact with N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. Due to its acute toxicity and sensitization potential, seek medical attention promptly for any significant exposure, especially if symptoms develop.

How to dispose of N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine properly?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine must be disposed of as hazardous chemical waste through licensed waste management companies. Due to its aquatic toxicity classification, prevent release to water systems or soil. Contact certified hazardous waste handlers who can ensure proper treatment and disposal according to local and EU regulations. Never dispose of via regular drainage systems or municipal waste collection.

How to transport N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III. Transport requires appropriate hazardous goods packaging, labeling, and documentation in compliance with ADR regulations. Vehicles must carry proper safety equipment and drivers need hazardous materials training certification. Ensure packages are properly secured and marked with required hazard labels during transportation.

Is N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine subject to specific regulations?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is subject to EU CLP regulation requiring appropriate hazard classification and labeling with GHS07, GHS08, and GHS09 pictograms. Under REACH regulation, it requires registration for import/manufacture above tonnage thresholds. While not currently listed as SVHC, its reproductive toxicity classification may trigger additional regulatory scrutiny. Transport is regulated under ADR as Class 9 dangerous goods.

Where to buy N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine in Europe?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is available through OYSI, a specialized European distributor of fine and specialty chemicals. OYSI provides this compound with complete regulatory documentation including safety data sheets, certificates of analysis, and proper hazard labeling. As experienced chemical distributors, OYSI ensures compliance with EU regulations and provides technical support for safe handling and application guidance to European customers.

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N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.