N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine

C18H35NO2

CAS118134-30-8
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Warning

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Identification

CAS Number
118134-30-8
UN Number
3082
Index Number
612-150-00-X
PubChem CID
86160

Physical-chemical properties

Molecular Formula
C18H35NO2
Molar Mass
297.50 g/mol
IUPAC Name
N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine

Chemical Identifiers

InChI
InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3
InChI Key
PUYXTUJWRLOUCW-UHFFFAOYSA-N

Overview

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine (CAS 118134-30-8) is a complex tertiary amine compound with spiro-cyclic structural features and significant toxicological properties. This specialized organic compound belongs to the family of substituted amines characterized by its unique spirocyclic framework incorporating a 1,4-dioxaspiro[4.5]decane core structure. With a molecular formula of C18H35NO2 and molecular weight of 297.5 g/mol, this substance exhibits considerable structural complexity due to the presence of both the tert-butyl substituent and the N-ethylpropan-1-amine functional group attached to the spirocyclic system. The compound presents significant safety considerations, classified under multiple hazard categories including reproductive toxicity (Category 2), acute toxicity (Category 4), and specific target organ toxicity following repeated exposure (Category 2). The substance also demonstrates skin irritation and sensitization properties, along with aquatic toxicity concerns. These characteristics necessitate careful handling procedures and appropriate personal protective equipment during industrial operations. Due to its complex molecular architecture and amine functionality, this compound finds applications in specialized chemical synthesis as an intermediate in pharmaceutical development, particularly in drug discovery programs targeting specific receptor systems. The spirocyclic structure makes it valuable in medicinal chemistry research where conformational rigidity is desired. Additionally, it serves as a building block in the synthesis of advanced materials and specialty chemicals requiring specific stereochemical properties. Unlike simpler aromatic compounds such as 1,4-dichlorobenzene, this sophisticated amine requires specialized handling protocols due to its multiple hazard classifications and structural complexity. OYSI provides this high-purity specialty chemical to qualified industrial customers across Europe, ensuring full regulatory compliance and technical support for demanding applications.

Safety & Classification

Warning
Classification:

Repr. 2; Acute Tox. 4; Acute Tox. 4; Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Skin Sens. 1; Aquati...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H315

Causes skin irritation.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3082
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameSpiroxamin (ISO)
Marine PollutantNo

Frequently Asked Questions

What is N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is an organic compound with the molecular formula C18H35NO2 and CAS number 118134-30-8. This chemical substance has a molecular weight of 297.5 g/mol and features a complex spirocyclic structure containing both dioxaspiro and amine functional groups. It is classified as hazardous with multiple health and environmental warnings, requiring careful handling in industrial applications.

What are the physicochemical properties of N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is a molecular compound with a molar mass of 297.5 g/mol. The substance contains tertiary amine functionality combined with a spirocyclic dioxane ring system and a tert-butyl group, suggesting it is likely a liquid or low-melting solid at room temperature. Its complex organic structure with both hydrophobic and hydrophilic regions may influence its solubility characteristics in various solvents.

What is N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine used for?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is used as a specialized chemical intermediate in various industrial applications. Its unique spirocyclic structure and amine functionality make it valuable in pharmaceutical research, fine chemical synthesis, and potentially as a building block for more complex organic molecules. The compound may also serve in specialty chemical formulations where its specific structural properties are required.

How to safely handle N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine requires careful handling due to its multiple hazard classifications including acute toxicity, skin irritation, and sensitization. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation and avoid skin contact and inhalation. The substance carries GHS08, GHS07, and GHS09 pictograms with a Warning signal word, indicating significant health and environmental hazards.

How to properly store N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly sealed and protected from light and moisture. Due to its skin sensitizing and irritant properties, store in areas with restricted access and appropriate secondary containment. Maintain storage temperatures as recommended by the supplier and ensure compatibility with storage materials to prevent container degradation.

What to do in case of contact with N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine exposure requires immediate action due to its skin irritant and sensitizing properties. For skin contact, immediately wash with plenty of soap and water for at least 15 minutes and remove contaminated clothing. If inhaled, move to fresh air immediately. For eye contact, rinse thoroughly with water for at least 15 minutes. Seek medical attention if irritation persists or if ingestion occurs.

How to properly dispose of N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine must be disposed of according to local, national, and international environmental regulations due to its hazardous classification. The substance requires specialized hazardous waste treatment and cannot be disposed of in regular waste streams. Contact licensed hazardous waste disposal companies and ensure proper documentation. Consider incineration at appropriate high-temperature facilities capable of handling organic compounds with potential environmental impact.

How to transport N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is classified under ADR Class 9 (Miscellaneous dangerous goods), Packing Group III. This classification requires appropriate packaging, labeling, and documentation for road transport. Use UN-approved packaging suitable for Class 9 materials and ensure proper hazard labels and transport documents are present. The substance must be transported by qualified personnel familiar with hazardous materials regulations and emergency response procedures.

Is N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine subject to special regulations?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is subject to REACH and CLP regulations within the European Union due to its hazardous classification. The substance is not currently identified as a Substance of Very High Concern (SVHC). Companies handling this chemical must comply with safety data sheet requirements, proper classification and labeling under CLP, and potential registration obligations under REACH depending on quantities and use patterns.

Where to buy N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine in Europe?

N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to industrial customers across Europe with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures quality standards and handles the complex logistics associated with hazardous materials transport while maintaining full regulatory compliance throughout European markets.

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N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine is a dangerous good. We support you with labeling, packaging, and transport documentation.

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Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.