1,4-dichloro-2-nitrobenzene

1,4-dichloro-2-nitrobenzene is an aromatic organic compound with the molecular formula C6H3Cl2NO2 and CAS number 89-61-2. This chemical features a benzene ring substituted with two chlorine atoms at positions 1 and 4, and a nitro group at position 2. With a molecular weight of 192 g/mol, it belongs to the class of halogenated nitroaromatic compounds and is classified as a Category 1B carcinogen under GHS regulations.

1,4-dichloro-2-nitrobenzene typically appears as a pale yellow to light brown crystalline solid at room temperature. The compound has limited water solubility due to its aromatic and halogenated nature, but shows better solubility in organic solvents such as alcohols and ethers. Its molecular structure contributes to its stability under normal conditions, though it may decompose under extreme heat or in the presence of strong reducing agents.

1,4-dichloro-2-nitrobenzene serves primarily as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is commonly used in the production of dyes, pigments, and other aromatic compounds through various chemical transformations. The compound's reactive chlorine and nitro substituents make it valuable for nucleophilic substitution reactions and reduction processes in organic synthesis applications within the chemical manufacturing industry.

1,4-dichloro-2-nitrobenzene requires strict safety measures due to its carcinogenic classification (Carc. 1B). Personnel must wear appropriate PPE including chemical-resistant gloves, protective clothing, and respiratory protection when handling this substance. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Direct skin and eye contact must be avoided, and proper hygiene practices should be followed to prevent contamination.

1,4-dichloro-2-nitrobenzene should be stored in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible materials. The substance must be kept in tightly sealed, labeled containers made of compatible materials. Storage areas should be designed to contain spills and prevent environmental release. Given its carcinogenic properties, access should be restricted to authorized personnel only, and appropriate safety signage must be displayed.

Immediate action is required upon contact with 1,4-dichloro-2-nitrobenzene due to its carcinogenic nature. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes while keeping eyelids open. If inhaled, move the person to fresh air immediately. Seek medical attention promptly in all cases of exposure.

1,4-dichloro-2-nitrobenzene must be disposed of as hazardous waste through licensed waste management companies in accordance with local, national, and EU regulations. The substance cannot be discharged to sewers, waterways, or regular waste streams due to its carcinogenic properties and environmental persistence. Waste containers must be properly labeled and handled by qualified personnel. Incineration at authorized high-temperature facilities is typically the preferred disposal method for this type of chemical.

1,4-dichloro-2-nitrobenzene is classified under ADR as Class 6.1 (Toxic substances), Packing Group III for transportation purposes. The substance must be packaged in UN-approved containers with proper labeling, marking, and documentation. Transport vehicles require appropriate placarding and emergency information. Only qualified drivers with hazardous materials training should handle the transportation, and emergency response procedures must be readily available during transit.

1,4-dichloro-2-nitrobenzene is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification as a Category 1B carcinogen. The substance carries the danger signal word and GHS08 pictogram indicating serious health hazards. Companies handling this chemical must comply with occupational exposure limits, risk assessment requirements, and worker protection measures. Additional restrictions may apply depending on specific uses and quantities handled.

1,4-dichloro-2-nitrobenzene is available through specialized chemical distributors across Europe, including OYSI, which serves as a reliable supplier of technical chemicals to European markets. Due to its hazardous classification, the substance is typically available only to qualified industrial users with appropriate safety infrastructure and regulatory compliance. Purchasers must meet specific requirements related to handling, storage, and use of carcinogenic substances under European legislation.