1,3-dichloro-2-methoxy-5-nitrobenzene

1,3-dichloro-2-methoxy-5-nitrobenzene is an aromatic organic compound with the molecular formula C7H5Cl2NO3 and CAS number 17742-69-7. This substituted benzene derivative features two chlorine atoms, one methoxy group, and one nitro group attached to the benzene ring. With a molecular weight of 222.02 g/mol, it is classified as a toxic substance requiring careful handling due to its acute toxicity and environmental hazards.

1,3-dichloro-2-methoxy-5-nitrobenzene typically appears as a solid crystalline material at room temperature. As a chlorinated aromatic compound with nitro and methoxy substituents, it exhibits limited water solubility but good solubility in organic solvents. The presence of electron-withdrawing groups (chlorine and nitro) and the electron-donating methoxy group creates a compound with moderate polarity and specific reactivity patterns typical of substituted nitrobenzenes.

1,3-dichloro-2-methoxy-5-nitrobenzene serves as an important chemical intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of agrochemicals, dyes, and specialized pharmaceutical compounds. The multiple functional groups on the benzene ring make it valuable for further chemical transformations, including reduction reactions to form corresponding anilines and substitution reactions for developing complex molecular structures.

1,3-dichloro-2-methoxy-5-nitrobenzene requires strict safety measures due to its Acute Tox. 3 classification and 'Danger' signal word. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Handle containers carefully and ensure proper grounding when transferring to prevent static electricity buildup.

1,3-dichloro-2-methoxy-5-nitrobenzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers upright and properly labeled according to GHS requirements with pictograms GHS06 and GHS09. Storage areas should be equipped with appropriate spill containment measures and restricted access. Avoid exposure to strong bases, reducing agents, and oxidizing materials that could cause dangerous reactions.

Immediate action is required if contact occurs with 1,3-dichloro-2-methoxy-5-nitrobenzene due to its acute toxicity. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. In case of eye contact, flush with water for 15 minutes. If ingested, do not induce vomiting. Seek immediate medical attention in all cases and provide safety data sheet information to medical personnel.

1,3-dichloro-2-methoxy-5-nitrobenzene must be disposed of as hazardous waste through licensed waste management companies in accordance with local and EU regulations. Due to its toxic and environmentally hazardous properties (Aquatic Chronic 2), it cannot be disposed of in regular waste streams. Incineration at authorized high-temperature facilities is typically the preferred disposal method. Maintain proper documentation of waste disposal and ensure compliance with REACH and waste framework directive requirements.

1,3-dichloro-2-methoxy-5-nitrobenzene is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. Packages must bear appropriate hazard labels and UN identification numbers. Transport vehicles require proper placarding and documentation including transport documents with emergency response information. Drivers must hold appropriate ADR certification for Class 6.1 substances. Packaging must meet UN specification standards and be properly sealed and labeled before shipment.

1,3-dichloro-2-methoxy-5-nitrobenzene is subject to REACH registration requirements and CLP regulation for classification and labeling within the EU. While not currently listed as a SVHC (Substance of Very High Concern), its Acute Tox. 3 and Aquatic Chronic 2 classifications require compliance with specific handling, storage, and disposal regulations. Users must maintain safety data sheets, implement appropriate risk management measures, and ensure worker protection according to occupational health and safety directives.

1,3-dichloro-2-methoxy-5-nitrobenzene is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with full regulatory compliance including proper CLP labeling, safety data sheets, and REACH documentation. As a professional chemical distributor, OYSI ensures quality standards and regulatory compliance for industrial and research applications. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.