8-azaspiro[4.5]decane-7,9-dione

8-azaspiro[4.5]decane-7,9-dione is an organic chemical compound with the molecular formula C9H13NO2 and CAS number 1075-89-4. This spirocyclic compound features a nitrogen atom incorporated into a bicyclic structure with two ketone groups. With a molecular weight of 167.2 g/mol, it belongs to the class of azaspirocyclic compounds and is classified as acutely toxic and chronically hazardous to aquatic environments.

8-azaspiro[4.5]decane-7,9-dione is a solid organic compound at room temperature with a molecular weight of 167.2 g/mol. The compound contains both nitrogen and oxygen functional groups within its spirocyclic structure, which influences its polarity and potential solubility characteristics. Specific physical properties such as melting point, boiling point, and detailed solubility data require experimental determination or specialized chemical databases for precise values.

8-azaspiro[4.5]decane-7,9-dione is primarily used as a chemical intermediate in pharmaceutical and fine chemical synthesis. Its spirocyclic structure makes it valuable as a building block for developing complex organic molecules, particularly in medicinal chemistry research. The compound may also serve as a precursor for synthesizing biologically active compounds or as a specialty chemical in advanced material applications requiring specific structural motifs.

8-azaspiro[4.5]decane-7,9-dione must be handled with extreme caution due to its Acute Toxicity Category 3 classification. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Avoid skin contact, inhalation, and ingestion. Work in a fume hood when possible, wear appropriate laboratory clothing, and ensure emergency shower and eyewash stations are accessible. Handle only the minimum quantities necessary for your application.

8-azaspiro[4.5]decane-7,9-dione should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and properly labeled with hazard information. Store away from heat sources, direct sunlight, and moisture. Due to its acute toxicity classification, maintain secure storage with restricted access and appropriate containment measures. Regularly inspect containers for damage or leaks, and maintain an inventory record for regulatory compliance purposes.

Immediate action is required upon contact with 8-azaspiro[4.5]decane-7,9-dione due to its acute toxicity. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with clean water for 15 minutes. If ingested, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet and contact poison control or emergency services when necessary.

8-azaspiro[4.5]decane-7,9-dione must be disposed of as hazardous chemical waste through licensed waste management companies. Never dispose of this compound in regular waste streams, sewers, or the environment due to its toxicity and aquatic hazard classification. Collect waste in appropriate containers, properly labeled with contents and hazard information. Contact certified hazardous waste disposal services and follow local environmental regulations. Maintain disposal records for regulatory compliance and traceability.

8-azaspiro[4.5]decane-7,9-dione is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Shipments must include proper shipping names, UN numbers, and hazard labels. Only use approved packaging materials and ensure compliance with international transport regulations. Carriers must be certified for dangerous goods transport and follow specific handling procedures during transit.

8-azaspiro[4.5]decane-7,9-dione is subject to various chemical regulations including REACH registration requirements for European markets and CLP classification obligations. The compound is not listed as a Substance of Very High Concern (SVHC), but its Acute Toxicity 3 and Aquatic Chronic 2 classifications impose specific labeling, safety data sheet, and handling requirements. Users must comply with occupational health regulations and environmental protection laws in their respective jurisdictions.

8-azaspiro[4.5]decane-7,9-dione is available through OYSI, a European chemical distributor specializing in fine chemicals and pharmaceutical intermediates. OYSI provides this compound with full regulatory compliance, including proper documentation, safety data sheets, and transport arrangements according to ADR requirements. As an established European supplier, OYSI ensures quality standards and reliable supply chains for laboratory and industrial applications requiring this specialized spirocyclic compound.