8-azaspiro[4.5]decane-7,9-dione

8-azaspiro[4.5]decane-7,9-dione is an organic chemical compound with the molecular formula C9H13NO2 and CAS number 1075-89-4. This spirocyclic compound features a nitrogen atom integrated into a unique bicyclic structure with two ketone functional groups. With a molecular weight of 167.2 g/mol, it belongs to the family of azaspiro compounds and is classified as acutely toxic and chronically hazardous to aquatic environments.

8-azaspiro[4.5]decane-7,9-dione exhibits properties typical of nitrogen-containing heterocycles with ketone functionalities. The compound's spirocyclic structure influences its physical characteristics, including melting point, solubility, and stability. As an organic compound with both polar ketone groups and a nitrogen heteroatom, it likely demonstrates moderate polarity affecting its solubility in various solvents. Specific physical data such as appearance and odor should be verified through material safety data sheets.

8-azaspiro[4.5]decane-7,9-dione serves primarily as an intermediate in pharmaceutical and fine chemical synthesis. Its unique spirocyclic structure makes it valuable for developing complex molecular architectures in medicinal chemistry. The compound may be utilized in research applications for synthesizing bioactive molecules, particularly those requiring nitrogen-containing heterocyclic scaffolds. Its specific applications depend on the target molecules being synthesized and the desired pharmaceutical or research outcomes.

8-azaspiro[4.5]decane-7,9-dione requires careful handling due to its Acute Tox. 3 classification and Danger signal word. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and lab coats. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure emergency shower and eyewash stations are accessible. Handle quantities according to risk assessment protocols and maintain awareness of GHS06 pictogram warnings.

8-azaspiro[4.5]decane-7,9-dione should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Due to its acute toxicity classification, storage areas must be secure and accessible only to trained personnel. Keep containers properly labeled with hazard information and avoid exposure to extreme temperatures or moisture. Storage facilities should comply with local regulations for toxic substances and include appropriate secondary containment measures to prevent environmental release.

Immediate action is required following contact with 8-azaspiro[4.5]decane-7,9-dione due to its acute toxicity. For skin contact, remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. If eye contact occurs, flush immediately with water and seek medical attention. In case of inhalation, move to fresh air and monitor breathing. For ingestion, do not induce vomiting and seek immediate medical care. Always consult the safety data sheet for specific first aid measures.

8-azaspiro[4.5]decane-7,9-dione waste must be disposed of according to local and national hazardous waste regulations due to its acute toxicity and aquatic chronic hazard classifications. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this substance through regular waste streams or pour into drains. Waste containers should be clearly labeled and stored securely until collection. Disposal methods may include high-temperature incineration at authorized facilities following applicable environmental regulations.

8-azaspiro[4.5]decane-7,9-dione is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation. This classification requires specific packaging, labeling, and documentation according to dangerous goods regulations. Packages must display appropriate hazard labels and UN identification numbers. Transportation should only be conducted by trained personnel familiar with dangerous goods handling procedures. Proper shipping papers and emergency response information must accompany shipments, and vehicles must comply with ADR requirements for toxic substance transport.

8-azaspiro[4.5]decane-7,9-dione is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification for hazard communication. The substance is not currently listed as a Substance of Very High Concern (SVHC). Companies handling this chemical must comply with occupational safety regulations, environmental protection laws, and proper hazard classification under GHS. Users should verify current regulatory status and any restrictions that may apply to their specific applications and quantities.

8-azaspiro[4.5]decane-7,9-dione is available through OYSI, a trusted European distributor of specialty chemicals and pharmaceutical intermediates. OYSI provides quality chemical products to research institutions, pharmaceutical companies, and industrial customers across Europe. For procurement, contact OYSI directly to discuss quantities, specifications, and delivery requirements. As a specialized chemical, availability may vary, so advance ordering is recommended to ensure supply continuity for your research or manufacturing needs.