1-nitropropane

C3H7NO2

CAS108-03-2
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
108-03-2
EC Number
203-544-9
UN Number
2608
Index Number
609-001-00-6
PubChem CID
7903

Physical-chemical properties

Molecular Formula
C3H7NO2
Molar Mass
89.09 g/mol
IUPAC Name
1-nitropropane

Chemical Identifiers

InChI
InChI=1S/C3H7NO2/c1-2-3-4(5)6/h2-3H2,1H3
InChI Key
JSZOAYXJRCEYSX-UHFFFAOYSA-N

Overview

1-nitropropane (CAS 108-03-2) is an organic nitro compound with flammable properties and moderate toxicity characteristics. This primary nitroalkane serves as an important industrial solvent and chemical intermediate in various manufacturing processes. With its molecular formula C3H7NO2 and molar mass of 89.09 g/mol, 1-nitropropane exhibits the characteristic properties of aliphatic nitro compounds, including good solvency power for resins, polymers, and organic materials. The compound appears as a colorless liquid with a mild, characteristic odor. From a safety perspective, 1-nitropropane is classified as a flammable liquid (Category 3) and presents acute toxicity hazards through oral, dermal, and inhalation exposure routes. The GHS classification includes pictograms GHS02 (flame) and GHS07 (exclamation mark) with a "Warning" signal word, indicating the need for appropriate handling precautions. As an ADR Class 3 substance, it requires specific transportation and storage protocols to ensure safe handling throughout the supply chain. Industrial applications of 1-nitropropane include its use as a solvent in paint and coating formulations, particularly in nitrocellulose-based systems, as well as in adhesive manufacturing and as a chemical intermediate for pharmaceutical and agrochemical synthesis. Unlike related compounds such as 4-methylpent-3-en-2-one, 1-nitropropane offers unique polarity characteristics that make it valuable for specific extraction and purification processes. OYSI maintains reliable supply chains for 1-nitropropane to support European industrial customers requiring this specialized nitroalkane for their technical applications, ensuring consistent quality and regulatory compliance across all deliveries.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2608
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping Name1-Nitropropan
Marine PollutantNo

Frequently Asked Questions

What is 1-nitropropane?

1-nitropropane is an organic nitro compound with the molecular formula C3H7NO2 and CAS number 108-03-2. It belongs to the family of nitroalkanes, characterized by a nitro group (-NO2) attached to a three-carbon propane chain. With a molecular weight of 89.09 g/mol, this chemical is classified as a flammable liquid and presents moderate acute toxicity risks, requiring careful handling in industrial applications.

What are the physicochemical properties of 1-nitropropane?

1-nitropropane is a colorless to pale yellow liquid at room temperature with a characteristic sweet, fruity odor. It has a boiling point of approximately 131°C and a density of about 1.0 g/cm³. The compound is moderately soluble in water and miscible with most organic solvents including alcohols, ethers, and hydrocarbons, making it versatile for various chemical processes and formulations.

What is 1-nitropropane used for?

1-nitropropane serves primarily as a solvent in industrial applications, particularly for resins, waxes, and dyes. It is used in rocket propellant formulations, as an intermediate in pharmaceutical synthesis, and in the production of other nitro compounds. The chemical also finds application in fuel additives and as a component in specialized cleaning formulations due to its excellent solvating properties.

How to handle 1-nitropropane safely?

Safe handling of 1-nitropropane requires appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid contact with heat sources, sparks, and open flames due to its flammable nature. Use non-sparking tools and ensure proper grounding of equipment to prevent static electricity buildup during transfer operations.

How to store 1-nitropropane correctly?

1-nitropropane must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers away from incompatible materials such as strong oxidizers, reducing agents, and bases. Storage areas should be equipped with appropriate fire suppression systems and maintained at temperatures below 25°C to prevent vapor accumulation and ensure product stability.

What to do in case of contact with 1-nitropropane?

In case of skin contact with 1-nitropropane, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with plenty of water for 15 minutes and seek medical attention. If inhaled, move the person to fresh air and provide respiratory support if needed. Seek immediate medical attention for any exposure and provide the safety data sheet to medical personnel.

How to dispose of 1-nitropropane appropriately?

1-nitropropane waste must be disposed of according to local and national hazardous waste regulations. The substance cannot be disposed of in regular waste streams due to its flammable and toxic properties. Contact licensed hazardous waste disposal companies for proper treatment, which typically involves incineration at high temperatures in specialized facilities. Always consult local environmental authorities for specific disposal requirements and documentation procedures.

How to transport 1-nitropropane?

1-nitropropane is classified under ADR Class 3 (Flammable Liquids), Packing Group III for transportation purposes. It must be packaged in UN-approved containers with appropriate labeling including GHS02 (flame) and GHS07 (exclamation mark) pictograms. Transport vehicles must comply with ADR regulations for Class 3 substances, including proper ventilation, fire extinguishing equipment, and trained personnel with appropriate transport documentation.

Is 1-nitropropane subject to specific regulations?

1-nitropropane is regulated under the CLP Regulation with classifications including Flam. Liq. 3 and Acute Tox. 4, requiring appropriate labeling with warning signal word and specific hazard statements. It falls under REACH registration requirements for manufacturers and importers. The substance is not currently listed as a SVHC (Substance of Very High Concern), but users must comply with occupational exposure limits and workplace safety regulations.

Where to buy 1-nitropropane in Europe?

1-nitropropane is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across the continent. OYSI provides high-quality 1-nitropropane with complete regulatory documentation, safety data sheets, and technical support. As an established chemical distributor, OYSI ensures compliance with European regulations and offers reliable supply chain solutions for businesses requiring this specialized nitro compound for their industrial applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.