1-nitropropane

C3H7NO2

CAS108-03-2
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
108-03-2
EC Number
203-544-9
UN Number
2608
Index Number
609-001-00-6
PubChem CID
7903

Physical-chemical properties

Molecular Formula
C3H7NO2
Molar Mass
89.09 g/mol
IUPAC Name
1-nitropropane

Chemical Identifiers

InChI
InChI=1S/C3H7NO2/c1-2-3-4(5)6/h2-3H2,1H3
InChI Key
JSZOAYXJRCEYSX-UHFFFAOYSA-N

Overview

1-Nitropropane (CAS 108-03-2) is an organic nitro compound with flammable liquid properties and moderate toxicity characteristics. This versatile chemical intermediate belongs to the family of primary nitroalkanes and serves as an important building block in various industrial processes. With its molecular formula C3H7NO2 and molecular weight of 89.09 g/mol, 1-nitropropane exhibits typical properties of aliphatic nitro compounds, making it valuable for synthetic chemistry applications. The compound is classified as a flammable liquid (Class 3) with acute toxicity warnings, requiring proper handling protocols and safety measures during storage and use. Its GHS02 and GHS07 pictograms indicate both fire hazards and health risks, necessitating appropriate personal protective equipment and ventilation systems in workplace environments. The substance falls under ADR Class 3 for transportation purposes, reflecting its flammable nature. Industrial applications of 1-nitropropane include its use as a solvent for various organic materials, particularly in specialized coating formulations and extraction processes. It also serves as a chemical intermediate in the synthesis of pharmaceuticals and agricultural chemicals, where its nitro group functionality provides reactive pathways for further molecular modifications. Additionally, the compound finds application in the production of specialty polymers and as a component in certain fuel additives. Like related compounds such as 4-methylpent-3-en-2-one, 1-nitropropane requires careful handling due to its chemical reactivity and safety profile. The substance shares some solvent properties with other organic intermediates, though its unique nitro functionality distinguishes its specific applications. OYSI maintains reliable supply chains for 1-nitropropane to support European industrial customers requiring this specialized chemical intermediate.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2608
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping Name1-Nitropropan
Marine PollutantNo

Frequently Asked Questions

What is 1-nitropropane?

1-nitropropane is an organic chemical compound with the molecular formula C3H7NO2 and CAS number 108-03-2. It belongs to the nitroalkane family, featuring a nitro group (-NO2) attached to the first carbon of a propane chain. With a molecular weight of 89.09 g/mol, this flammable liquid is classified as hazardous under GHS regulations, displaying warning pictogrammes for flammability and acute toxicity.

What are the physicochemical properties of 1-nitropropane?

1-nitropropane is a colorless to pale yellow liquid with a characteristic sweet odor. It has a boiling point of approximately 131°C and a melting point of -108°C. The compound is slightly soluble in water but miscible with most organic solvents including alcohols, ethers, and hydrocarbons. It has a density of about 1.00 g/cm³ and exhibits moderate volatility at room temperature.

What is 1-nitropropane used for?

1-nitropropane serves primarily as an industrial solvent and chemical intermediate. It is used in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. The compound also finds application as a fuel additive, particularly in racing fuels due to its oxygen content. Additionally, it serves as a solvent for resins, waxes, and dyestuffs, and as a propellant component in some specialized applications.

How to handle 1-nitropropane safely?

1-nitropropane requires careful handling due to its flammable and toxic nature. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or use local exhaust ventilation to minimize vapor exposure. Avoid sources of ignition, heat, and sparks. Prevent contact with skin, eyes, and inhalation of vapors. Use appropriate grounding and bonding procedures during transfer operations.

How to store 1-nitropropane correctly?

1-nitropropane must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use tightly sealed, chemically compatible containers, preferably made of stainless steel or approved plastics. Keep away from strong acids, bases, and oxidizing agents to prevent dangerous reactions. Storage temperature should not exceed 25°C, and containers should be protected from direct sunlight and physical damage.

What to do in case of contact with 1-nitropropane?

Immediate action is required upon contact with 1-nitropropane. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move person to fresh air and seek medical care if symptoms persist. For ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of 1-nitropropane appropriately?

1-nitropropane disposal must comply with local, national, and international environmental regulations. The compound cannot be disposed of in regular waste streams due to its hazardous classification. Contact licensed waste disposal companies for proper treatment, which may include incineration at approved facilities or chemical treatment. Empty containers should also be handled as hazardous waste. Always consult with environmental authorities for specific disposal requirements in your jurisdiction.

How to transport 1-nitropropane?

1-nitropropane is classified under ADR Class 3 (flammable liquids), Packing Group III for transportation. It requires appropriate hazardous goods packaging, labeling, and documentation according to international dangerous goods regulations. Vehicles must carry proper placarding, and drivers need hazmat certification. The compound should be transported in approved containers with proper segregation from incompatible materials and adequate securing to prevent spillage during transit.

Is 1-nitropropane subject to specific regulations?

1-nitropropane is regulated under various chemical safety frameworks including REACH in Europe, where it requires registration for commercial use. It falls under CLP regulation for classification, labeling, and packaging requirements. The compound is not currently listed as a SVHC (Substance of Very High Concern). Users must comply with workplace exposure limits, transport regulations (ADR), and environmental discharge restrictions as specified by local authorities.

Where to buy 1-nitropropane in Europe?

1-nitropropane is available through OYSI, a European distributor specializing in technical chemicals. As an established chemical supplier, OYSI can provide this compound with proper documentation, safety data sheets, and regulatory compliance certificates. Professional customers can contact OYSI directly to inquire about availability, packaging options, and delivery throughout Europe. Ensure your intended use complies with local regulations before purchasing this regulated chemical substance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.