Cyclohexanone

C6H10O

cyclohexanone

CAS108-94-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
108-94-1
EC Number
203-631-1
UN Number
1915
Index Number
606-010-00-7
PubChem CID
7967

Physical-chemical properties

Molecular Formula
C6H10O
Molar Mass
98.14 g/mol
IUPAC Name
cyclohexanone

Chemical Identifiers

InChI
InChI=1S/C6H10O/c7-6-4-2-1-3-5-6/h1-5H2
InChI Key
JHIVVAPYMSGYDF-UHFFFAOYSA-N

Overview

Cyclohexanone (CAS 108-94-1) is a cyclic ketone with strong solvent properties and characteristic peppermint-like odor. This important industrial chemical serves as a versatile intermediate in organic synthesis and manufacturing processes across multiple sectors. With its molecular formula C6H10O and molecular weight of 98.14 g/mol, cyclohexanone features a six-membered saturated ring structure with a ketone functional group, making it highly reactive and useful for various chemical transformations. The compound appears as a colorless to pale yellow liquid that is miscible with most organic solvents and slightly soluble in water. From a safety perspective, cyclohexanone is classified as a flammable liquid (Category 3) and carries acute toxicity warnings (Category 4), requiring appropriate handling precautions including proper ventilation, fire prevention measures, and personal protective equipment. The substance displays GHS pictograms for flammability and health hazards, emphasizing the need for trained personnel and established safety protocols during storage and use. Industrially, cyclohexanone finds primary application as a precursor in nylon production, where it serves as an intermediate in the synthesis of caprolactam and adipic acid. The chemical also functions as an effective solvent for resins, waxes, and polymers in coating formulations, and plays a crucial role in pharmaceutical manufacturing as a building block for various active compounds. Like related ketones such as heptan-4-one, cyclohexanone's solvent properties make it valuable in extraction and purification processes. OYSI supplies high-quality cyclohexanone to meet diverse industrial requirements across Europe, supporting customers with reliable sourcing and technical expertise.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1915
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameCyclohexanon
Marine PollutantNo

Frequently Asked Questions

What is cyclohexanone?

Cyclohexanone is a cyclic ketone with the chemical formula C6H10O and CAS number 108-94-1. It is an important industrial solvent and chemical intermediate with a molecular weight of 98.14 g/mol. This organic compound appears as a colorless to pale yellow liquid with a characteristic acetone-like odor. Cyclohexanone is classified as a flammable liquid (Category 3) and acutely toxic substance (Category 4), requiring proper handling and safety precautions in industrial applications.

What are the physicochemical properties of cyclohexanone?

Cyclohexanone is a colorless to slightly yellow liquid at room temperature with a distinctive sweet, acetone-like odor. It has a molecular formula of C6H10O and a molar mass of 98.14 g/mol. The compound is moderately soluble in water and completely miscible with most organic solvents including alcohols, ethers, and hydrocarbons. It has a boiling point around 155°C and a flash point of approximately 44°C, making it a flammable liquid requiring careful handling.

What is cyclohexanone used for?

Cyclohexanone is primarily used as an industrial solvent for resins, waxes, rubber, and plastics. It serves as a key intermediate in the production of caprolactam, which is essential for manufacturing nylon-6 fibers and plastics. The compound is also utilized in paint strippers, wood stains, spot removers, and as a solvent in various coating formulations. Additionally, it finds applications in the pharmaceutical industry as a reaction medium and in the production of adipic acid.

How to handle cyclohexanone safely?

Cyclohexanone requires careful handling due to its flammable and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in poorly ventilated areas. Work should be conducted in well-ventilated spaces away from ignition sources, heat, and flames. Avoid skin and eye contact, and prevent inhalation of vapors. Use appropriate grounding and bonding procedures when transferring the liquid to prevent static electricity buildup. Emergency shower and eyewash facilities should be readily accessible.

How to store cyclohexanone correctly?

Cyclohexanone should be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use appropriate containers made of compatible materials and ensure proper grounding of storage tanks. Keep containers tightly closed and away from incompatible substances such as strong oxidizing agents and strong bases. Storage areas should be equipped with fire suppression systems and spill containment measures. Maintain storage temperatures below the flash point and regularly inspect containers for leaks or damage.

What to do in case of contact with cyclohexanone?

Cyclohexanone exposure requires immediate action depending on the contact route. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any significant exposure incident.

How to dispose of cyclohexanone properly?

Cyclohexanone disposal must comply with local, national, and EU waste regulations as a hazardous chemical waste. The substance should be collected in appropriate containers and delivered to authorized waste treatment facilities for proper disposal or incineration at high temperatures. Never discharge cyclohexanone into sewers, waterways, or soil. Small quantities may be suitable for solvent recovery through distillation. Always consult with certified waste management companies and follow the waste classification codes according to the European Waste Catalogue.

How to transport cyclohexanone?

Cyclohexanone is classified under ADR as Class 3 (flammable liquids), Packing Group III for transportation purposes. Packages must bear appropriate hazard labels including GHS02 (flame) and GHS07 (exclamation mark) pictograms with 'Warning' signal word. Transport vehicles require proper placarding and emergency equipment. Containers must be properly secured, and drivers need ADR certification for dangerous goods transport. Shipping documentation must include the proper shipping name, UN number, and emergency contact information according to European transport regulations.

Is cyclohexanone subject to specific regulations?

Cyclohexanone is regulated under the EU CLP Regulation as a flammable liquid (Category 3) and acute toxicity substance (Category 4), requiring appropriate classification and labeling. It falls under REACH regulation requiring registration for manufacturing or importing above one tonne annually. The substance is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits and workplace safety regulations. Industrial users should maintain safety data sheets and implement appropriate risk management measures according to EU chemical legislation.

Where to buy cyclohexanone in Europe?

Cyclohexanone is available through OYSI, a established European distributor of industrial chemicals serving multiple countries across the continent. OYSI provides reliable supply chains for various grades and quantities of cyclohexanone to meet industrial requirements. The company ensures compliance with European regulations including REACH registration and proper documentation. For specific availability, technical specifications, and delivery options in your region, contact OYSI directly through their European distribution network to discuss your cyclohexanone procurement needs.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.