Cyclohexanone

C6H10O

cyclohexanone

CAS108-94-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
108-94-1
EC Number
203-631-1
UN Number
1915
Index Number
606-010-00-7
PubChem CID
7967

Physical-chemical properties

Molecular Formula
C6H10O
Molar Mass
98.14 g/mol
IUPAC Name
cyclohexanone

Chemical Identifiers

InChI
InChI=1S/C6H10O/c7-6-4-2-1-3-5-6/h1-5H2
InChI Key
JHIVVAPYMSGYDF-UHFFFAOYSA-N

Overview

Cyclohexanone (CAS 108-94-1) is a cyclic ketone with strong solvent properties and characteristic odor used in industrial chemical processes. This colorless organic compound belongs to the ketone family and serves as a crucial intermediate in numerous chemical manufacturing processes. With its molecular formula C6H10O and molar mass of 98.14 g/mol, cyclohexanone exhibits excellent dissolving capabilities for various organic materials, making it highly valuable in industrial applications. The compound is characterized by its distinctive sweet, acetone-like odor and relatively high boiling point, which contributes to its effectiveness as a solvent and chemical intermediate. From a safety perspective, cyclohexanone is classified as a flammable liquid (Category 3) and carries acute toxicity warnings (Category 4), requiring careful handling protocols. The substance displays GHS02 and GHS07 pictograms with a "Warning" signal word, indicating moderate hazard levels that necessitate appropriate personal protective equipment and ventilation systems during use. Its ADR classification as Class 3 material requires specific transportation and storage procedures to ensure safe handling throughout the supply chain. Cyclohexanone finds primary applications in the production of nylon 6 and nylon 66 through its conversion to caprolactam, serving as a key building block in polymer manufacturing. Additionally, it functions as an effective solvent for paints, lacquers, and resins, particularly in industrial coating formulations. The compound also serves as a chemical intermediate in pharmaceutical synthesis and specialty chemical production. Within the broader ketone family, cyclohexanone shares certain solvent characteristics with compounds like heptan-4-one, though its cyclic structure provides unique properties for specific industrial processes. OYSI maintains reliable supplies of high-quality cyclohexanone to support European industrial customers' manufacturing requirements.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1915
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameCyclohexanon
Marine PollutantNo

Frequently Asked Questions

What is cyclohexanone?

Cyclohexanone is a colorless organic ketone with the chemical formula C6H10O and CAS number 108-94-1. It is a cyclic compound featuring a six-membered carbon ring with one ketone functional group. With a molecular weight of 98.14 g/mol, cyclohexanone is classified as a flammable liquid and presents moderate acute toxicity hazards, requiring appropriate safety precautions during handling and storage.

What are the physicochemical properties of cyclohexanone?

Cyclohexanone is a colorless to pale yellow liquid at room temperature with a characteristic sweet, acetone-like odor. It has excellent solvent properties and is miscible with most organic solvents including alcohols, ethers, and hydrocarbons. The compound is slightly soluble in water and exhibits moderate volatility. Its ketone structure makes it reactive toward nucleophiles and suitable for various chemical transformations.

What is cyclohexanone used for?

Cyclohexanone is primarily used as an industrial solvent for resins, waxes, and rubber compounds. It serves as a key intermediate in the production of nylon-6 and nylon-6,6 through its conversion to caprolactam and adipic acid. Additional applications include paint strippers, wood stains, spot removers, and as a chemical intermediate in pharmaceutical and agrochemical synthesis.

How to handle cyclohexanone safely?

Cyclohexanone requires careful handling due to its flammable and toxic properties. Essential safety measures include wearing appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or use fume extraction systems to prevent vapor inhalation. Keep away from ignition sources, hot surfaces, and oxidizing agents. Always follow proper grounding procedures to prevent static electricity buildup.

How to store cyclohexanone correctly?

Cyclohexanone should be stored in tightly closed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers grounded and use explosion-proof electrical equipment in storage areas. Store separately from strong oxidizing agents, strong bases, and incompatible materials. Maintain storage temperatures below 25°C and ensure adequate fire suppression systems are available in storage facilities.

What to do in case of contact with cyclohexanone?

In case of skin contact with cyclohexanone, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms persist.

How to dispose of cyclohexanone appropriately?

Cyclohexanone disposal must comply with local and national hazardous waste regulations as it is classified as hazardous waste. The compound should be collected in appropriate containers and disposed of through licensed hazardous waste treatment facilities. Incineration at high temperatures with proper emission controls is typically the preferred disposal method. Never dispose of cyclohexanone down drains, sewers, or into the environment.

How to transport cyclohexanone?

Cyclohexanone is classified under ADR as Class 3 (flammable liquids), Packing Group III, requiring specific transport regulations. It must be packaged in approved containers with proper labeling including GHS02 and GHS07 pictograms and 'Warning' signal word. Transport vehicles must carry appropriate safety equipment and documentation. Drivers require ADR certification for dangerous goods transport, and specific routing restrictions may apply.

Is cyclohexanone subject to particular regulations?

Cyclohexanone is subject to various European regulations including REACH registration requirements and CLP classification as Flam. Liq. 3 and Acute Tox. 4. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits, safety data sheet requirements, and proper labeling according to GHS standards. Industrial users may need to implement risk management measures and worker protection programs.

Where to buy cyclohexanone in Europe?

Cyclohexanone is available through OYSI, a European distributor specializing in technical chemical products. OYSI provides high-quality cyclohexanone with proper documentation, safety data sheets, and regulatory compliance for industrial and professional applications. As an established chemical distributor, OYSI ensures reliable supply chains and technical support throughout Europe while maintaining strict quality standards and regulatory compliance for all chemical products.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.