1-methoxy-2-nitrobenzene

1-methoxy-2-nitrobenzene is an aromatic organic compound with the molecular formula C7H7NO3 and CAS number 91-23-6. This chemical features a benzene ring substituted with both a methoxy group (-OCH3) and a nitro group (-NO2) in ortho positions. With a molecular weight of 153.14 g/mol, it is classified as a Category 1B carcinogen and acute toxicant, requiring careful handling in industrial applications.

1-methoxy-2-nitrobenzene is typically a yellow to orange crystalline solid or liquid at room temperature. The compound exhibits low water solubility due to its aromatic nature but dissolves readily in organic solvents such as ethanol, acetone, and benzene. It has a characteristic aromatic odor and is sensitive to light and heat, which can cause decomposition or color changes over time.

1-methoxy-2-nitrobenzene serves primarily as an intermediate in organic synthesis and pharmaceutical manufacturing. It is commonly used in the production of dyes, pigments, and other aromatic compounds through reduction or substitution reactions. The compound also finds applications in research laboratories for synthetic chemistry studies and as a precursor for manufacturing various specialty chemicals in the fine chemical industry.

1-methoxy-2-nitrobenzene requires strict safety measures due to its carcinogenic and toxic properties. Personnel must wear appropriate PPE including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin contact, inhalation, and ingestion. Use only in closed systems when possible and ensure proper training for all handlers.

1-methoxy-2-nitrobenzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep separate from strong oxidizing agents, reducing agents, and incompatible materials. Storage areas must be equipped with appropriate containment measures and fire suppression systems. Containers should be clearly labeled and stored in secondary containment to prevent environmental release.

Immediate action is required for any contact with 1-methoxy-2-nitrobenzene. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with clean water for 15 minutes. Seek immediate medical attention in all cases and provide the safety data sheet to medical personnel.

1-methoxy-2-nitrobenzene must be disposed of as hazardous waste according to local, national, and EU regulations. The compound cannot be disposed of through regular waste streams due to its carcinogenic properties. Contact licensed hazardous waste disposal companies for proper collection and treatment. Incineration at high temperatures in specialized facilities is typically the preferred disposal method, following all applicable environmental regulations.

1-methoxy-2-nitrobenzene is classified under ADR as Class 6.1 (Toxic substances), Packing Group III. Transportation requires proper packaging in UN-approved containers with appropriate labeling including GHS08 and GHS07 pictograms and 'Danger' signal word. Vehicles must carry proper documentation, emergency response information, and drivers need ADR certification for toxic substances transport. Comply with all modal transport regulations.

1-methoxy-2-nitrobenzene is subject to comprehensive EU chemical regulations including REACH registration requirements and CLP classification as Carcinogenic 1B and Acute Tox. 4. It requires safety data sheets, proper labeling with GHS pictograms, and workplace exposure controls. The substance may be subject to authorization procedures and restrictions depending on specific uses. Companies must comply with occupational health regulations and worker protection measures.

1-methoxy-2-nitrobenzene is available through OYSI, a trusted European distributor of specialty chemicals and industrial products. As an experienced chemical supplier, OYSI provides quality-assured products with complete regulatory documentation including safety data sheets and certificates of analysis. Their European distribution network ensures reliable supply chains while maintaining full compliance with REACH and other applicable chemical regulations for professional customers.