Naphthalen-2-amine

C10H9N

naphthalen-2-amine

CAS91-59-8
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
91-59-8
EC Number
202-080-4
UN Number
1650
Index Number
612-022-00-3
PubChem CID
7057

Physical-chemical properties

Molecular Formula
C10H9N
Molar Mass
143.18 g/mol
IUPAC Name
naphthalen-2-amine

Chemical Identifiers

InChI
InChI=1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2
InChI Key
JBIJLHTVPXGSAM-UHFFFAOYSA-N

Overview

Naphthalen-2-amine (CAS 91-59-8) is an aromatic amine compound with significant industrial applications and classification as a Category 1A carcinogen. This organic chemical compound, also known as β-naphthylamine, belongs to the family of polycyclic aromatic amines and consists of a naphthalene ring system with an amino group attached at the 2-position. With the molecular formula C10H9N and a molecular weight of 143.18 g/mol, naphthalen-2-amine appears as crystalline solids at room temperature and exhibits characteristic aromatic amine properties. The compound carries serious safety considerations due to its classification under CLP regulation as Carcinogenic Category 1A, Acute Toxicity Category 4, and Aquatic Chronic Toxicity Category 2. These hazard classifications require strict handling protocols, appropriate personal protective equipment, and adherence to occupational exposure limits. The GHS pictograms GHS08, GHS07, and GHS09 indicate health hazards, acute toxicity, and environmental dangers respectively, while the ADR Class 6.1 classification governs its transportation as toxic substances. Industrial applications of naphthalen-2-amine primarily include its use as an intermediate in dye synthesis, particularly for azo dyes and pigments, where it serves as a crucial building block for various colorants. The compound also finds application in the production of antioxidants for rubber and polymer industries, as well as in the synthesis of pharmaceutical intermediates. Related compounds such as naphthalen-2-amine hydrochloride share similar applications but offer different solubility profiles for specific manufacturing processes. OYSI maintains availability of naphthalen-2-amine for qualified industrial customers with appropriate handling capabilities and regulatory compliance requirements.

Safety & Classification

Danger
Classification:

Carc. 1A; Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1650
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping Namebeta-Naphthylamin, fest
Marine PollutantNo

Frequently Asked Questions

What is naphthalen-2-amine?

Naphthalen-2-amine is an aromatic amine compound with the molecular formula C10H9N and CAS number 91-59-8. This organic chemical consists of a naphthalene ring system with an amino group (-NH2) attached at the 2-position. With a molecular weight of 143.18 g/mol, it belongs to the family of polycyclic aromatic amines and is classified as a Category 1A carcinogen, requiring strict handling protocols in industrial applications.

What are the physicochemical properties of naphthalen-2-amine?

Naphthalen-2-amine is a solid crystalline compound that typically appears as white to light brown crystals or powder. It has a characteristic aromatic amine odor and exhibits limited solubility in water but dissolves readily in organic solvents such as alcohol and ether. The compound is stable under normal conditions but may darken upon exposure to air and light due to oxidation processes.

What is naphthalen-2-amine used for?

Naphthalen-2-amine is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceutical compounds. It serves as a key building block in the production of azo dyes, antioxidants, and rubber chemicals. The compound is also utilized in research applications and as a precursor for various organic synthesis reactions in the chemical industry, particularly in specialty chemical manufacturing.

How to handle naphthalen-2-amine safely?

Naphthalen-2-amine requires strict safety measures due to its carcinogenic properties. Personal protective equipment must include chemical-resistant gloves, safety goggles, and respiratory protection with appropriate filters. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin contact and ensure proper training on carcinogen handling procedures before use.

How to store naphthalen-2-amine correctly?

Naphthalen-2-amine should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Keep containers protected from moisture and incompatible materials such as strong oxidizing agents. Storage areas must be clearly labeled with appropriate hazard warnings and equipped with proper ventilation systems to prevent vapor accumulation.

What to do in case of contact with naphthalen-2-amine?

Immediate action is required upon contact with naphthalen-2-amine. For skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly for any exposure, emphasizing the carcinogenic nature of the substance.

How to dispose of naphthalen-2-amine appropriately?

Naphthalen-2-amine disposal must comply with local and international hazardous waste regulations due to its carcinogenic classification. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment facilities. Contact licensed waste disposal companies experienced in handling carcinogenic materials. Maintain proper documentation and manifests for all disposal activities as required by environmental regulations.

How to transport naphthalen-2-amine?

Naphthalen-2-amine is classified under ADR Class 6.1 (toxic substances) with Packing Group II, indicating moderate toxicity requiring specific transport protocols. Packages must be properly labeled with appropriate hazard markings and transported by qualified carriers familiar with dangerous goods regulations. Shipping documentation must include the correct UN number and hazard declarations in accordance with international transport regulations.

Is naphthalen-2-amine subject to specific regulations?

Naphthalen-2-amine is subject to strict regulations under REACH and CLP regulations in Europe due to its Category 1A carcinogen classification. The substance requires authorization for many uses and is subject to restriction measures. Occupational exposure limits are strictly enforced, and users must implement risk management measures. Regular monitoring and reporting may be required depending on the specific application and quantities used.

Where to buy naphthalen-2-amine in Europe?

Naphthalen-2-amine is available through OYSI, a specialized European distributor of technical chemicals. As a carcinogenic substance, purchase requires proper authorization and compliance with regulatory requirements. OYSI provides technical support and regulatory guidance to ensure proper handling and compliance. Contact OYSI directly to discuss specific requirements, quantities, and regulatory documentation needed for your application.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.