Naphthalen-2-amine
C10H9N
naphthalen-2-amine
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Identification
- CAS Number
- 91-59-8
- EC Number
- 202-080-4
- UN Number
- 1650
- Index Number
- 612-022-00-3
- PubChem CID
- 7057
Physical-chemical properties
- Molecular Formula
- C10H9N
- Molar Mass
- 143.18 g/mol
- IUPAC Name
- naphthalen-2-amine
Chemical Identifiers
- InChI
- InChI=1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2
- InChI Key
- JBIJLHTVPXGSAM-UHFFFAOYSA-N
Overview
Naphthalen-2-amine (CAS 91-59-8) is an aromatic amine compound with significant industrial applications and notable carcinogenic properties. This organic chemical compound, also known by its IUPAC designation naphthalen-2-amine, represents a critical intermediate in various industrial processes despite its classification as a Category 1A carcinogen. With the molecular formula C10H9N and a molecular weight of 143.18 g/mol, this aromatic amine consists of a naphthalene ring system with an amino group attached at the 2-position. The compound's structure makes it particularly valuable in synthetic chemistry applications, though its use requires stringent safety protocols due to its hazardous nature. The substance carries multiple danger classifications including acute toxicity (Category 4) and chronic aquatic toxicity (Category 2), necessitating careful handling procedures. Its ADR transport classification of 6.1 reflects its toxic properties, while the required GHS pictograms (GHS08, GHS07, GHS09) emphasize the carcinogenic, acute toxicity, and environmental hazards. These safety considerations are paramount when working with naphthalen-2-amine, as exposure can pose serious health risks. Industrial applications primarily focus on the production of dyes and pigments, where naphthalen-2-amine serves as a key building block for various colorants. The compound also finds use in the synthesis of pharmaceutical intermediates and specialty chemicals. Related compounds such as naphthalen-2-amine hydrochloride share similar applications but offer different solubility and handling characteristics. Additionally, compounds like 4-[(4-aminophenyl)methyl]aniline represent alternative aromatic amines used in comparable industrial processes. OYSI maintains availability of naphthalen-2-amine for qualified industrial customers with appropriate handling capabilities and regulatory compliance requirements.
Safety & Classification
Carc. 1A; Acute Tox. 4 *; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1650 |
| ADR Class | 6.1 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | beta-Naphthylamin, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is naphthalen-2-amine?
Naphthalen-2-amine is an aromatic amine compound with the molecular formula C10H9N and CAS number 91-59-8. It consists of a naphthalene ring system with an amino group attached at the 2-position. This organic chemical has a molecular weight of 143.18 g/mol and is classified as a Category 1A carcinogen, making it a substance of significant health concern requiring careful handling and strict safety protocols.
What are the physicochemical properties of naphthalen-2-amine?
Naphthalen-2-amine is a solid crystalline compound at room temperature, typically appearing as white to pale yellow crystals or powder. It has limited water solubility but dissolves readily in organic solvents such as ethanol and acetone. The compound exhibits characteristic aromatic amine properties and may darken upon exposure to light and air due to oxidation processes.
What is naphthalen-2-amine used for?
Naphthalen-2-amine is primarily used as an intermediate in the synthesis of dyes, pigments, and other organic compounds. It serves as a building block in the production of azo dyes, antioxidants, and rubber chemicals. Due to its carcinogenic classification, its industrial applications are highly regulated and restricted in many jurisdictions, with strict controls on occupational exposure.
How to handle naphthalen-2-amine safely?
Naphthalen-2-amine requires strict safety protocols due to its carcinogenic properties. Essential protective equipment includes impervious gloves, protective clothing, and respiratory protection to prevent inhalation. Work should be conducted in well-ventilated areas or under fume extraction systems. Avoid skin contact, inhalation, and ingestion. Regular health monitoring of workers is recommended, and access should be restricted to trained personnel only.
How to store naphthalen-2-amine correctly?
Naphthalen-2-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Storage areas must be secure and accessible only to authorized personnel due to carcinogenic hazards. Keep away from incompatible materials such as strong oxidizing agents. Containers should be properly labeled according to GHS requirements and stored in designated chemical storage facilities.
What to do in case of contact with naphthalen-2-amine?
Immediate action is required for any contact with naphthalen-2-amine. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water. In case of eye contact, flush immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure incident.
How to dispose of naphthalen-2-amine appropriately?
Naphthalen-2-amine disposal must comply with local and national hazardous waste regulations due to its carcinogenic classification. The substance cannot be disposed of in regular waste streams and requires specialized hazardous waste treatment facilities. Incineration at high temperatures in approved facilities is typically the preferred disposal method. Waste generators must use licensed waste disposal companies and maintain proper documentation for regulatory compliance.
How to transport naphthalen-2-amine?
Naphthalen-2-amine is classified under ADR Class 6.1 (toxic substances) Packing Group II, indicating significant transport hazards. Packages must bear appropriate hazard labels including GHS pictograms GHS07, GHS08, and GHS09. Transportation requires proper shipping documentation, trained personnel, and compliance with dangerous goods regulations. Vehicles must carry appropriate emergency equipment and follow designated transport routes where applicable.
Is naphthalen-2-amine subject to specific regulations?
Naphthalen-2-amine is subject to extensive regulatory oversight under REACH and CLP regulations in Europe due to its carcinogenic classification. While not currently listed as an SVHC, it faces strict occupational exposure limits and may be subject to authorization requirements. Many countries have implemented workplace restrictions and banned its use in consumer products. Manufacturers and users must comply with comprehensive safety data sheet requirements and exposure assessment obligations.
Where to buy naphthalen-2-amine in Europe?
Naphthalen-2-amine is available through specialized chemical distributors in Europe, including OYSI, which supplies technical-grade chemicals to industrial customers. Due to its hazardous classification, procurement requires proper documentation, safety qualifications, and compliance with regulatory requirements. Buyers must demonstrate legitimate industrial use and appropriate handling capabilities. Contact OYSI directly for availability, specifications, and regulatory compliance documentation for your specific application requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.