1-chloro-4-(chloromethyl)benzene
C7H6Cl2
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Identification
- CAS Number
- 104-83-6
- EC Number
- 203-242-7
- UN Number
- 3427
- PubChem CID
- 7723
Physical-chemical properties
- Molecular Formula
- C7H6Cl2
- Molar Mass
- 161.03 g/mol
- IUPAC Name
- 1-chloro-4-(chloromethyl)benzene
Chemical Identifiers
- InChI
- InChI=1S/C7H6Cl2/c8-5-6-1-3-7(9)4-2-6/h1-4H,5H2
- InChI Key
- JQZAEUFPPSRDOP-UHFFFAOYSA-N
Overview
1-chloro-4-(chloromethyl)benzene (CAS 104-83-6) is an aromatic organochlorine compound with two chlorine substituents on a benzene ring structure. This dichlorinated benzene derivative, also known by its molecular formula C7H6Cl2, represents an important intermediate in organic synthesis and chemical manufacturing. With a molecular weight of 161.03 g/mol, this compound features a benzene ring substituted with a chlorine atom at the para position and a chloromethyl group, creating a versatile building block for various chemical transformations. The presence of two reactive chlorine centers provides multiple pathways for nucleophilic substitution reactions, making it particularly valuable in pharmaceutical and agrochemical synthesis. From a safety perspective, 1-chloro-4-(chloromethyl)benzene is classified under ADR Class 6.1, indicating its toxic nature and requiring appropriate handling precautions. Professional users must implement proper ventilation, personal protective equipment, and storage protocols when working with this material. The compound's reactivity profile demands careful consideration of temperature and moisture control during storage and processing. Industrial applications include its use as a synthetic intermediate in pharmaceutical manufacturing, where it serves as a precursor for various drug compounds. The chemical industry also utilizes this substance in the production of specialty chemicals and polymer additives. Its structural similarity to other aromatic compounds like 4-nitroaniline makes it valuable in comparative synthetic methodologies. Additionally, it finds application in research and development laboratories for organic synthesis projects requiring selective chlorination patterns. OYSI maintains reliable supply chains for 1-chloro-4-(chloromethyl)benzene, supporting European chemical manufacturers and research institutions with consistent quality and technical documentation.
Safety & Classification
No Hazard Classification
This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.
Transport (ADR)
| UN Number | 3427 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | p-Chlorbenzylchlorid, rein, flüssig* |
| Marine Pollutant | No |
Frequently Asked Questions
What is 1-chloro-4-(chloromethyl)benzene?
1-chloro-4-(chloromethyl)benzene is an organochlorine compound with the molecular formula C7H6Cl2 and CAS number 104-83-6. This aromatic compound features a benzene ring substituted with both a chlorine atom and a chloromethyl group in para positions. With a molecular weight of 161.03 g/mol, it serves as an important intermediate in organic synthesis and chemical manufacturing processes.
What are the physicochemical properties of 1-chloro-4-(chloromethyl)benzene?
1-chloro-4-(chloromethyl)benzene is typically a colorless to pale yellow liquid at room temperature with a characteristic aromatic odor. The compound has limited solubility in water due to its chlorinated aromatic structure but dissolves readily in organic solvents such as alcohols, ethers, and hydrocarbons. Its boiling point and other physical properties make it suitable for various industrial applications requiring organic intermediates.
What is 1-chloro-4-(chloromethyl)benzene used for?
1-chloro-4-(chloromethyl)benzene serves primarily as a chemical intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is commonly used in the production of various organic compounds through substitution reactions, particularly in manufacturing processes requiring chlorinated aromatic building blocks. The compound finds applications in research laboratories and industrial facilities focused on fine chemical synthesis and drug development.
How to handle 1-chloro-4-(chloromethyl)benzene safely?
1-chloro-4-(chloromethyl)benzene should be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure proper training on chemical handling procedures. Keep away from heat sources and incompatible materials during use.
How to store 1-chloro-4-(chloromethyl)benzene correctly?
1-chloro-4-(chloromethyl)benzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep away from strong oxidizing agents, bases, and reactive metals to prevent unwanted reactions. Storage areas should be equipped with appropriate spill containment measures and maintained at stable temperatures to preserve product quality and safety.
What to do in case of contact with 1-chloro-4-(chloromethyl)benzene?
In case of skin contact with 1-chloro-4-(chloromethyl)benzene, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention.
How to dispose of 1-chloro-4-(chloromethyl)benzene appropriately?
1-chloro-4-(chloromethyl)benzene must be disposed of as hazardous chemical waste in accordance with local, national, and EU regulations. Contact licensed waste disposal companies specialized in handling organochlorine compounds. Never dispose of this chemical down drains, sewers, or in regular trash. Maintain proper documentation for waste disposal tracking and ensure compliance with all applicable environmental regulations.
How to transport 1-chloro-4-(chloromethyl)benzene?
1-chloro-4-(chloromethyl)benzene is classified under ADR as Class 6.1 (toxic substances), Packing Group III for transportation purposes. It must be packaged in approved containers meeting UN specifications and properly labeled with appropriate hazard markings. Transportation should comply with ADR regulations for dangerous goods, including proper documentation, vehicle requirements, and driver training for hazardous material transport.
Is 1-chloro-4-(chloromethyl)benzene subject to particular regulations?
1-chloro-4-(chloromethyl)benzene is subject to REACH regulation for chemical registration and evaluation within the European Union. It must comply with CLP regulation for classification, labeling, and packaging requirements. The substance is not currently listed as a Substance of Very High Concern (SVHC). Users must ensure compliance with local occupational safety regulations and environmental protection laws governing chemical handling and use.
Where to buy 1-chloro-4-(chloromethyl)benzene in Europe?
1-chloro-4-(chloromethyl)benzene is available through OYSI, a European distributor of specialty chemicals serving various industries across the region. As an established chemical supplier, OYSI provides quality products with proper documentation and regulatory compliance support. For procurement inquiries, technical specifications, and availability information, contact OYSI directly to discuss your specific requirements and obtain detailed product information and pricing.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.