1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea is an organosulfur compound with the molecular formula C7H12N4O3S2 and CAS number 30043-49-3. This chemical features a thiadiazole ring system combined with a substituted urea group and an ethylsulfonyl substituent. With a molecular weight of 264.3 g/mol, it is classified as a skin sensitizer and poses aquatic toxicity risks, requiring careful handling in industrial applications.

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea is a solid compound at room temperature with a molecular weight of 264.3 g/mol. The compound contains multiple polar functional groups including sulfonyl, thiadiazole, and urea moieties, which influence its solubility characteristics. Its chemical structure suggests moderate polarity, and the presence of nitrogen and sulfur heteroatoms contributes to its specific reactivity profile and stability under normal conditions.

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. Its thiadiazole-urea structure makes it valuable for developing bioactive compounds, particularly in pesticide formulations and drug discovery programs. The compound serves as a building block for creating more complex molecules with enhanced biological activity, contributing to research and development in crop protection and pharmaceutical industries.

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea requires careful handling due to its skin sensitization properties. Essential safety measures include wearing protective gloves, safety glasses, and appropriate clothing to prevent skin contact. Work should be conducted in well-ventilated areas or under fume hoods. Avoid generating dust and ensure proper hygiene practices. Emergency eyewash and safety shower facilities should be readily accessible when handling this compound.

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials and ensure proper labeling with hazard information. Storage areas should have appropriate spill containment measures and access restrictions to prevent environmental release and unauthorized handling.

Immediate action is required if contact occurs with 1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air. Seek medical attention if irritation persists or sensitization symptoms develop.

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea must be disposed of through licensed hazardous waste contractors due to its aquatic toxicity classification. The compound cannot be discharged to sewers or waterways and requires specialized treatment. Contaminated packaging should also be treated as hazardous waste. Disposal must comply with local and EU waste regulations, including proper documentation and tracking throughout the disposal process.

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation for road transport. Shipments must include proper shipping names, UN numbers, and hazard labels. Transport vehicles should carry appropriate emergency equipment, and drivers must have relevant dangerous goods training certification according to ADR regulations.

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea is subject to REACH registration requirements in Europe and must comply with CLP classification and labeling regulations. The compound is classified as Skin Sens. 1, Aquatic Acute 1, and Aquatic Chronic 1, requiring appropriate hazard communication. While not currently listed as a SVHC, users must ensure compliance with occupational exposure limits and environmental protection measures under relevant EU legislation.

1-(5-ethylsulfonyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to pharmaceutical, agrochemical, and research industries across Europe with proper documentation and regulatory compliance. As a professional chemical distributor, OYSI ensures quality standards and provides technical support for safe handling and application guidance to meet your specific industrial requirements.