5-amino-4-chloro-2-phenylpyridazin-3-one

5-amino-4-chloro-2-phenylpyridazin-3-one is an organic chemical compound belonging to the pyridazinone family with the molecular formula C10H8ClN3O. This substance has a molecular weight of 221.64 g/mol and is characterized by the presence of amino, chloro, and phenyl functional groups on a pyridazinone ring structure. It is classified as a skin sensitizer and poses environmental hazards to aquatic life.

5-amino-4-chloro-2-phenylpyridazin-3-one is a solid compound at room temperature with a molecular weight of 221.64 g/mol. The presence of amino and chloro substituents affects its polarity and solubility characteristics. Its exact physical appearance, odor, and detailed solubility data depend on purity and crystalline form. The compound's structure suggests moderate polarity due to the combination of polar amino and chloro groups with the aromatic phenyl ring.

5-amino-4-chloro-2-phenylpyridazin-3-one is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. Its pyridazinone structure makes it valuable for developing bioactive compounds, particularly in medicinal chemistry research. The compound serves as a building block for creating more complex molecules with potential therapeutic or agricultural applications. It may also be used in specialized chemical research and development projects requiring this specific molecular framework.

5-amino-4-chloro-2-phenylpyridazin-3-one must be handled with appropriate personal protective equipment due to its skin sensitization potential. Wear protective gloves, safety glasses, and suitable clothing to prevent skin contact. Ensure adequate ventilation in work areas and avoid creating dust. Use in a well-ventilated area or under a fume hood when possible. The compound requires careful handling to prevent environmental release due to its aquatic toxicity classification.

5-amino-4-chloro-2-phenylpyridazin-3-one should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and protected from moisture and light. Store away from heat sources and oxidizing agents. The storage area should be equipped with appropriate containment measures to prevent environmental contamination. Follow local regulations for chemical storage and maintain proper inventory records for this regulated substance.

Immediate action is required if contact occurs with 5-amino-4-chloro-2-phenylpyridazin-3-one due to its skin sensitization properties. For skin contact, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for 15 minutes. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or if sensitization symptoms develop.

5-amino-4-chloro-2-phenylpyridazin-3-one must be disposed of through authorized hazardous waste disposal facilities due to its environmental classification. The compound cannot be disposed of in regular waste streams due to its aquatic toxicity. Contact licensed waste management companies specializing in chemical disposal. Follow local and national regulations for hazardous waste classification and transport. Ensure proper documentation and tracking of waste disposal activities as required by environmental authorities.

5-amino-4-chloro-2-phenylpyridazin-3-one is classified as ADR Class 9 (Miscellaneous Dangerous Goods), Packing Group III for transportation purposes. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Transport must comply with ADR requirements including proper packaging specifications, hazard labels, and transport documentation. Only authorized carriers trained in dangerous goods transport should handle shipments of this substance.

5-amino-4-chloro-2-phenylpyridazin-3-one is subject to standard REACH and CLP regulations in Europe but is not currently listed as a Substance of Very High Concern (SVHC). The compound must comply with classification, labeling, and packaging requirements under CLP regulation due to its hazard classification. Users must follow safety data sheet requirements and implement appropriate risk management measures. Registration or notification requirements may apply depending on annual tonnage and intended use.

5-amino-4-chloro-2-phenylpyridazin-3-one is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with appropriate documentation including safety data sheets and certificates of analysis. As a professional chemical distributor, OYSI ensures compliance with European regulations and proper handling procedures. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.