5-amino-4-chloro-2-phenylpyridazin-3-one

5-amino-4-chloro-2-phenylpyridazin-3-one is a synthetic organic compound belonging to the pyridazinone family with CAS number 1698-60-8. This chemical features a pyridazinone core structure substituted with amino, chloro, and phenyl groups. With a molecular formula of C10H8ClN3O and molecular weight of 221.64 g/mol, it is classified as a skin sensitizer and poses environmental hazards to aquatic life.

5-amino-4-chloro-2-phenylpyridazin-3-one is a solid organic compound with a molecular weight of 221.64 g/mol and molecular formula C10H8ClN3O. The compound contains multiple functional groups including amino, chloro, and carbonyl moieties within a heterocyclic structure. Its exact physical appearance, solubility, and melting point require specific analytical characterization for detailed specifications.

5-amino-4-chloro-2-phenylpyridazin-3-one is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. Its pyridazinone structure makes it valuable for developing bioactive compounds, particularly in medicinal chemistry research. The compound serves as a building block for creating more complex molecules with potential therapeutic or agricultural applications, though specific end-use applications depend on further chemical modifications.

5-amino-4-chloro-2-phenylpyridazin-3-one requires careful handling due to its skin sensitization properties (Skin Sens. 1). Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation in work areas and avoid direct skin contact. Follow standard chemical handling procedures, maintain good hygiene practices, and have emergency washing facilities readily available.

5-amino-4-chloro-2-phenylpyridazin-3-one should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and protected from moisture and light. Due to its environmental hazard classification (Aquatic Acute 1, Aquatic Chronic 1), ensure storage areas have appropriate containment measures to prevent environmental release. Store away from oxidizing agents and strong acids or bases.

In case of skin contact with 5-amino-4-chloro-2-phenylpyridazin-3-one, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air. Seek medical attention if irritation persists or symptoms develop, especially given its skin sensitization properties.

5-amino-4-chloro-2-phenylpyridazin-3-one must be disposed of according to local and national environmental regulations due to its aquatic toxicity classification. Contact licensed waste disposal companies for proper handling and treatment. Do not discharge to sewers, waterways, or soil. Incineration at authorized facilities may be appropriate for small quantities, but always consult with waste management professionals for compliant disposal methods.

5-amino-4-chloro-2-phenylpyridazin-3-one is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transport purposes. This classification requires appropriate packaging, labeling, and documentation according to ADR regulations. Use UN-specification packaging and ensure proper hazard labels are affixed. Transport documentation must include the correct shipping name and hazard class information.

5-amino-4-chloro-2-phenylpyridazin-3-one is subject to CLP regulation classification as Skin Sens. 1, Aquatic Acute 1, and Aquatic Chronic 1, requiring appropriate labeling with Warning signal word and GHS07/GHS09 pictograms. It is not currently listed as a SVHC under REACH regulation. Companies must comply with standard chemical registration, notification, and safety data sheet requirements within the EU regulatory framework.

5-amino-4-chloro-2-phenylpyridazin-3-one is available through OYSI, a European distributor of specialty chemicals. OYSI provides this compound to pharmaceutical, research, and industrial customers across Europe with proper documentation and regulatory compliance. Contact OYSI directly for availability, specifications, and ordering information. Ensure your application complies with local regulations before purchasing this sensitizing and environmentally hazardous substance.