4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine is an organic compound belonging to the pyrimidine family with the molecular formula C14H15N3 and CAS number 121552-61-2. This chemical features a pyrimidine ring substituted with cyclopropyl, methyl, and phenylamine groups, giving it a molecular weight of 225.29 g/mol. It is classified as a skin sensitizer and poses environmental hazards to aquatic life, requiring careful handling in industrial applications.

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine has a molecular weight of 225.29 g/mol and contains nitrogen heterocycles that influence its chemical behavior. The compound's physicochemical properties are determined by its pyrimidine core structure combined with cyclopropyl and phenyl substituents. Specific data regarding melting point, boiling point, solubility, and appearance should be obtained from detailed technical specifications or safety data sheets from suppliers.

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine is primarily used as an intermediate in pharmaceutical and chemical synthesis processes. Its pyrimidine structure makes it valuable for developing pharmaceutical compounds, agrochemicals, and specialty chemicals. The compound serves as a building block in organic synthesis where specific substitution patterns are required. Industrial applications may include research and development activities in medicinal chemistry and advanced material synthesis.

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine requires careful handling due to its skin sensitization properties (Skin Sens. 1). Personal protective equipment should include chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or under fume hoods to minimize inhalation exposure. Follow GHS07 warning pictogram guidelines and implement appropriate engineering controls to ensure worker safety during handling operations.

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed to prevent moisture absorption and contamination. Due to its aquatic toxicity classification, storage areas should have appropriate containment measures to prevent environmental release. Store separately from oxidizing agents and reactive chemicals, following standard protocols for organic compounds with sensitizing properties.

Immediate action is required for skin contact with 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine due to its sensitizing properties. Remove contaminated clothing and wash affected skin thoroughly with soap and water for at least 15 minutes. For eye contact, flush with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if symptoms develop or persist, and inform medical personnel about the skin sensitization hazard.

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine disposal must comply with local environmental regulations due to its Aquatic Acute 1 and Aquatic Chronic 1 classifications. The compound should never be discharged to sewers, waterways, or soil. Arrange disposal through licensed hazardous waste contractors who can handle aquatic-toxic substances. Incineration at appropriate high-temperature facilities may be suitable, but consultation with waste management specialists is recommended to ensure regulatory compliance.

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Packages must display proper shipping names, UN numbers, and hazard labels. Transport vehicles should carry appropriate emergency response information, and drivers must be trained in handling Class 9 dangerous goods according to ADR requirements.

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine is subject to European REACH regulation and CLP classification requirements but is not currently listed as a Substance of Very High Concern (SVHC). The compound must be classified with GHS07 and GHS09 pictograms and 'Warning' signal word. Suppliers must provide safety data sheets compliant with REACH Annex II requirements. Users should verify registration status and any restrictions under REACH before commercial use.

4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine is available through OYSI, a European distributor specializing in technical chemicals and pharmaceutical intermediates. OYSI provides reliable supply chains across Europe with appropriate regulatory documentation including safety data sheets and certificates of analysis. As a specialized chemical distributor, OYSI ensures proper handling, packaging, and transportation of this regulated substance according to European standards and customer requirements.