2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile
C8Cl4N2
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Identification
- CAS Number
- 1897-41-2
- EC Number
- 401-550-8
- UN Number
- 3077
- Index Number
- 608-016-00-5
- PubChem CID
- 74694
Physical-chemical properties
- Molecular Formula
- C8Cl4N2
- Molar Mass
- 265.90 g/mol
- IUPAC Name
- 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile
Chemical Identifiers
- InChI
- InChI=1S/C8Cl4N2/c9-5-3(1-13)6(10)8(12)4(2-14)7(5)11
- InChI Key
- TXRVDQMSXQKAPG-UHFFFAOYSA-N
Overview
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile (CAS 1897-41-2) is a highly chlorinated aromatic compound featuring both tetrachloro substitution and dicarbonitrile functional groups. This specialized chemical intermediate belongs to the family of polychlorinated benzene derivatives, characterized by its unique combination of four chlorine atoms and two nitrile groups positioned on a benzene ring. With the molecular formula C8Cl4N2 and a molecular weight of 265.9 g/mol, this compound exhibits distinct chemical properties that make it valuable in various industrial synthesis processes. The EC number 401-550-8 identifies this substance within European chemical regulations. The compound's safety profile requires careful handling due to its classification as a skin sensitizer (Skin Sens. 1) and its potential environmental impact, being classified as acutely and chronically hazardous to aquatic life (Aquatic Acute 1; Aquatic Chronic 1). This classification is reflected in the GHS07 and GHS09 pictograms, with a "Warning" signal word indicating moderate hazard levels. Transportation falls under ADR Class 9, designating it as a miscellaneous dangerous substance. Primary industrial applications include its use as a chemical intermediate in pharmaceutical synthesis, agrochemical production, and specialty polymer manufacturing. The compound's reactivity profile, influenced by both the electron-withdrawing chlorine substituents and the nitrile groups, makes it particularly useful in nucleophilic substitution reactions. Unlike simpler compounds such as 4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine, this tetrachlorinated derivative offers enhanced stability and selective reactivity patterns. OYSI maintains reliable supply chains for 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile to support European industrial customers requiring consistent quality and regulatory compliance.
Safety & Classification
Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Tunnel Code | - |
| Proper Shipping Name | 1,4-Dicyano-2,3,5,6-tetrachlorbenzen |
| Marine Pollutant | No |
Frequently Asked Questions
What is 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile is a chlorinated aromatic compound with the molecular formula C8Cl4N2 and CAS number 1897-41-2. This chemical features a benzene ring substituted with four chlorine atoms and two nitrile groups, giving it a molecular weight of 265.9 g/mol. It is classified as a skin sensitizer and poses aquatic toxicity risks, requiring careful handling in industrial applications.
What are the physicochemical properties of 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile is typically a solid crystalline compound at room temperature due to its highly substituted aromatic structure. The presence of four chlorine atoms and two nitrile groups makes it relatively polar, affecting its solubility characteristics. Its molecular weight of 265.9 g/mol and chlorinated structure contribute to its stability and persistence in various environments.
What is 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile used for?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile serves as an important intermediate in organic synthesis and chemical manufacturing processes. Its structure with multiple chlorine substituents and nitrile groups makes it valuable for producing specialized chemical compounds. It is commonly used in pharmaceutical synthesis, agrochemical development, and as a building block for advanced materials requiring specific electronic or chemical properties.
How to handle 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile safely?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile requires careful handling due to its skin sensitization properties (Skin Sens. 1). Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin contact and ensure proper hygiene measures after handling to prevent sensitization reactions.
How to store 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile correctly?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers properly labeled and store separately from strong bases, reducing agents, and food products. Due to its aquatic toxicity classification, ensure storage areas have appropriate containment measures to prevent environmental release in case of spills or container failure.
What to do in case of contact with 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile?
Immediate skin contact with 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile requires prompt removal of contaminated clothing and thorough washing of affected skin with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or if sensitization symptoms develop, as this compound is classified as Skin Sens. 1.
How to dispose of 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile properly?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile must be disposed of as hazardous waste through licensed waste management facilities due to its aquatic toxicity classification (Aquatic Acute 1, Aquatic Chronic 1). Never discharge to sewers, waterways, or soil. Contact certified hazardous waste disposal companies for proper treatment and disposal. Empty containers should also be handled as hazardous waste and disposed of according to local environmental regulations.
How to transport 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. It must be packaged in UN-approved containers with proper labeling including GHS07 and GHS09 pictograms and 'Warning' signal word. Transport documents must include the correct shipping name, UN number, and hazard class. Vehicles must carry appropriate emergency equipment and drivers require ADR training certification.
Is 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile subject to specific regulations?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile is subject to REACH regulation for registration, evaluation, and authorization in the European Union. It must comply with CLP regulation for classification, labeling, and packaging requirements, displaying GHS07 and GHS09 pictograms with 'Warning' signal word. The compound is not currently listed as a Substance of Very High Concern (SVHC), but users must still comply with occupational health and environmental protection regulations.
Where to buy 2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile in Europe?
2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile is available through OYSI, a specialized European distributor of technical chemicals serving industrial and research customers. OYSI provides this compound with full regulatory compliance including proper CLP labeling, safety data sheets, and documentation required under REACH regulation. Professional customers can contact OYSI for technical specifications, availability, and regulatory support for their specific applications across European markets.
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2,3,5,6-tetrachlorobenzene-1,4-dicarbonitrile is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.