Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate is an organic chemical compound with the molecular formula C17H18O4 and CAS number 132584-17-9. This substance has a molecular weight of 286.32 g/mol and contains both ester and phenoxy functional groups. It is classified as a skin sensitizer and poses environmental hazards to aquatic life, requiring appropriate handling precautions in industrial applications.

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate is a complex organic ester with a molecular weight of 286.32 g/mol. The compound features aromatic rings connected through an ether linkage and contains both hydroxyl and ester functional groups. Its structure includes a phenoxyphenyl moiety attached to a hydroxypropanoate backbone, making it moderately lipophilic due to its aromatic character and ester functionality.

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. Its unique structure with phenoxy and hydroxy-ester functionalities makes it valuable for developing active pharmaceutical ingredients and specialty chemicals. The compound may also serve in research applications for developing new materials or as a building block in complex organic syntheses.

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate must be handled with appropriate personal protective equipment due to its skin sensitization properties. Wear chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Ensure adequate ventilation in work areas and avoid generating dust or vapors. The substance requires Warning labeling with GHS07 and GHS09 pictograms indicating health and environmental hazards.

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep containers away from heat sources, ignition sources, and direct sunlight. Store separately from strong oxidizing agents and bases due to potential reactivity. Ensure proper labeling with hazard information and maintain inventory records for regulatory compliance and safety management.

In case of skin contact with ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or allergic reactions develop, as the substance is a known skin sensitizer.

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate must be disposed of as hazardous waste through authorized waste management companies due to its environmental classification. The substance cannot be discharged to sewers or the environment as it poses acute and chronic aquatic toxicity. Contact licensed hazardous waste disposal services and follow local and EU regulations for chemical waste disposal. Maintain proper waste documentation and disposal certificates.

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transport purposes. Use appropriate packaging that meets UN specification requirements for Class 9 materials. Ensure proper labeling with hazard diamonds and shipping documentation. Transport vehicles must comply with ADR regulations for Class 9 substances, and drivers require appropriate dangerous goods training certification.

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate is subject to EU REACH regulation and CLP classification requirements due to its hazardous properties. The substance is classified under CLP as Skin Sens. 1, Aquatic Acute 1, and Aquatic Chronic 1, requiring appropriate safety data sheets and hazard communication. It is not currently listed as an SVHC (Substance of Very High Concern), but users must comply with standard chemical safety regulations.

Ethyl 2-hydroxy-2-(4-phenoxyphenyl)propanoate is available through OYSI, a specialized European distributor of technical chemicals and pharmaceutical intermediates. OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support. As an established chemical distributor, OYSI ensures quality products and reliable supply chains for customers across Europe requiring this specialized organic intermediate for their applications.