5,7-dichloro-4-(4-fluorophenoxy)quinoline

5,7-dichloro-4-(4-fluorophenoxy)quinoline is an organic chemical compound with the molecular formula C15H8Cl2FNO and CAS number 124495-18-7. This quinoline derivative contains chlorine and fluorine substituents, giving it a molecular weight of 308.1 g/mol. It is classified as a skin sensitizer and poses aquatic toxicity risks, requiring careful handling in professional applications.

5,7-dichloro-4-(4-fluorophenoxy)quinoline is a halogenated quinoline compound with a molecular weight of 308.1 g/mol. The presence of chlorine and fluorine atoms in its structure influences its physicochemical properties, including solubility and stability. As a quinoline derivative, it typically appears as a solid at room temperature, though specific physical properties like melting point and solubility require detailed analysis.

5,7-dichloro-4-(4-fluorophenoxy)quinoline is primarily used as a chemical intermediate in pharmaceutical and agrochemical synthesis. Its quinoline structure makes it valuable for developing bioactive compounds, including potential antimicrobial and antiparasitic agents. The compound serves as a building block in medicinal chemistry research and may be used in the synthesis of more complex therapeutic molecules.

5,7-dichloro-4-(4-fluorophenoxy)quinoline requires careful handling due to its skin sensitization potential. Workers must wear protective gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods. Avoid generating dust and ensure proper hygiene practices, including thorough handwashing after handling.

5,7-dichloro-4-(4-fluorophenoxy)quinoline should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and properly labeled. Store away from heat sources, direct sunlight, and moisture. Due to its environmental hazard classification, ensure storage areas have appropriate containment measures to prevent environmental release in case of spills or leaks.

Immediate action is required if contact with 5,7-dichloro-4-(4-fluorophenoxy)quinoline occurs. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, rinse immediately with plenty of water for 15 minutes. Seek medical attention if irritation persists or if sensitization symptoms develop.

5,7-dichloro-4-(4-fluorophenoxy)quinoline must be disposed of as hazardous waste due to its aquatic toxicity classification. Contact licensed waste disposal companies for proper handling and treatment. Do not discharge into sewers, waterways, or soil. Follow local and national regulations for hazardous waste disposal. Contaminated packaging should also be treated as hazardous waste and disposed of accordingly.

5,7-dichloro-4-(4-fluorophenoxy)quinoline is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III. Transport must comply with ADR regulations for dangerous goods. Use appropriate packaging and labeling as specified for Class 9 materials. Ensure proper documentation and emergency response information accompanies shipments. Transport vehicles must be equipped according to ADR requirements for this classification.

5,7-dichloro-4-(4-fluorophenoxy)quinoline is subject to CLP regulation due to its hazard classification as Skin Sens. 1, Aquatic Acute 1, and Aquatic Chronic 1. It requires GHS07 and GHS09 pictograms with a "Warning" signal word. The substance is not currently listed as SVHC under REACH. Compliance with occupational exposure limits and environmental protection measures is mandatory.

5,7-dichloro-4-(4-fluorophenoxy)quinoline is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to professional users in pharmaceutical, research, and industrial applications. As a regulated chemical requiring proper handling and documentation, purchase is typically restricted to qualified professional customers with appropriate facilities and expertise for safe handling and use.