Trifluoromethylbenzene

Trifluoromethylbenzene is an aromatic organofluorine compound with the molecular formula C7H5F3 and CAS number 98-08-8. This chemical consists of a benzene ring substituted with a trifluoromethyl group (-CF3), giving it unique properties due to the presence of fluorine atoms. With a molecular weight of 146.11 g/mol, it belongs to the class of fluorinated aromatic compounds that are widely used in various industrial applications requiring specific chemical and physical properties.

Trifluoromethylbenzene is a clear, colorless liquid at room temperature with a characteristic aromatic odor. The compound has a boiling point of approximately 102-104°C and is relatively insoluble in water due to its hydrophobic nature, but shows good solubility in organic solvents such as alcohols, ethers, and hydrocarbons. The presence of three fluorine atoms significantly influences its chemical stability, electron-withdrawing properties, and overall reactivity compared to unsubstituted benzene.

Trifluoromethylbenzene is primarily used as an intermediate in pharmaceutical and agrochemical synthesis, serving as a building block for various fluorinated compounds. It finds applications in the production of specialty chemicals, including fluorinated pharmaceuticals, pesticides, and advanced materials. The compound is also utilized as a solvent in specific industrial processes and as a starting material for the synthesis of other fluorinated aromatic compounds where the trifluoromethyl group imparts desired biological or chemical properties.

Trifluoromethylbenzene must be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its flammable nature (Flam. Liq. 2). Work should be conducted in well-ventilated areas or under fume hoods to prevent vapor accumulation. Keep away from heat sources, sparks, and open flames as the substance poses fire hazards. Ensure proper grounding of equipment to prevent static electricity buildup during transfer operations.

Trifluoromethylbenzene should be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and direct sunlight due to its flammable liquid classification. Use appropriate containers made of compatible materials and ensure proper labeling with hazard information. Storage areas must be equipped with appropriate fire suppression systems and spill containment measures. Keep containers tightly closed when not in use and separate from incompatible materials such as strong oxidizing agents.

In case of skin contact with trifluoromethylbenzene, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult the safety data sheet for specific first aid measures.

Trifluoromethylbenzene must be disposed of as hazardous waste in accordance with local, national, and European waste regulations. The substance should be collected in appropriate containers and handed over to licensed waste disposal companies for proper treatment or incineration at authorized facilities. Do not pour down drains or release into the environment due to its Aquatic Chronic 2 classification. Contaminated packaging should also be treated as hazardous waste and disposed of accordingly.

Trifluoromethylbenzene is classified as ADR Class 3 (flammable liquids), Packing Group II, requiring specific transport regulations and packaging standards. Transportation must comply with ADR/RID regulations for dangerous goods, using appropriate UN-specification packaging and proper labeling with GHS02 and GHS09 pictograms. Vehicles must be equipped with appropriate safety equipment and drivers must have proper dangerous goods training. Transport documents must include all required hazard information and emergency response procedures.

Trifluoromethylbenzene is subject to various European chemical regulations including REACH registration requirements and CLP classification standards. The substance is classified under GHS with the signal word 'Danger' and specific hazard classes (Flam. Liq. 2, Aquatic Chronic 2). It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational safety regulations, environmental protection laws, and proper hazard communication requirements including safety data sheet provision.

Trifluoromethylbenzene is available through OYSI, a European chemical distributor specializing in technical and specialty chemicals. OYSI provides reliable supply chains across Europe with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical supplier, OYSI ensures product quality, appropriate packaging, and adherence to all transport and safety regulations. Contact OYSI directly for availability, specifications, and delivery options to meet your specific industrial requirements.