Prop-2-enenitrile

C3H3N

prop-2-enenitrile

CAS107-13-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
107-13-1
EC Number
203-466-5
UN Number
1093
Index Number
608-003-00-4
PubChem CID
7855

Physical-chemical properties

Molecular Formula
C3H3N
Molar Mass
53.06 g/mol
IUPAC Name
prop-2-enenitrile

Chemical Identifiers

InChI
InChI=1S/C3H3N/c1-2-3-4/h2H,1H2
InChI Key
NLHHRLWOUZZQLW-UHFFFAOYSA-N

Overview

Prop-2-enenitrile (CAS 107-13-1) is an unsaturated aliphatic nitrile with high reactivity and significant toxicological properties. This three-carbon nitrile compound, also known by its IUPAC designation prop-2-enenitrile, represents a critical intermediate in organic synthesis and industrial chemical processes. With the molecular formula C3H3N and a molecular mass of 53.06 g/mol, this colorless liquid exhibits the characteristic properties of both alkene and nitrile functional groups, making it exceptionally versatile yet hazardous in industrial applications. The compound's classification under multiple GHS hazard categories reflects its complex risk profile. As a Category 2 flammable liquid with ADR Class 3 designation, prop-2-enenitrile requires stringent handling protocols. Most notably, its Category 1B carcinogenic classification and multiple acute toxicity designations necessitate comprehensive safety measures including specialized ventilation, personal protective equipment, and emergency response procedures. The presence of GHS pictograms GHS02, GHS08, GHS06, GHS05, and GHS09 on safety documentation underscores the multi-faceted nature of its hazards. In industrial applications, prop-2-enenitrile serves primarily as a polymerization monomer for synthetic fiber production, particularly in acrylic fiber manufacturing. It also functions as an intermediate in pharmaceutical synthesis and serves as a building block for various specialty chemicals. Unlike structurally complex compounds such as (2-butyl-5-nitro-1-benzofuran-3-yl)-[4-[3-(dibutylamino)propoxy]phenyl]methanone, prop-2-enenitrile's simple structure enables diverse chemical transformations while maintaining cost-effectiveness in large-scale operations. OYSI maintains reliable supply chains for prop-2-enenitrile, supporting European industrial customers with comprehensive technical documentation and regulatory compliance support for this essential chemical intermediate.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Carc. 1B; Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; STOT SE 3; Skin Irrit. 2;...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H350

May cause cancer.

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H318

Causes serious eye damage.

H317

May cause an allergic skin reaction.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1093
ADR Class3
Packing GroupI
Tunnel CodeC/E
Proper Shipping NameAcrylnitril, stabilisiert
Marine PollutantNo

Frequently Asked Questions

What is prop-2-enenitrile?

Prop-2-enenitrile is an organic chemical compound with the molecular formula C3H3N and CAS number 107-13-1. This nitrile compound has a molecular weight of 53.06 g/mol and is classified as a highly hazardous substance with multiple danger classifications including carcinogenic, flammable, and acutely toxic properties. It requires careful handling due to its significant health and safety risks.

What are the physicochemical properties of prop-2-enenitrile?

Prop-2-enenitrile is a flammable liquid with the molecular formula C3H3N. It typically appears as a colorless to pale yellow liquid with a characteristic pungent odor. The compound has a molecular weight of 53.06 g/mol and exhibits high volatility. It is miscible with most organic solvents and has limited water solubility, making it suitable for various organic synthesis applications.

What is prop-2-enenitrile used for?

Prop-2-enenitrile is primarily used as an intermediate in organic synthesis and chemical manufacturing processes. It serves as a building block for producing various polymers, pharmaceuticals, and specialty chemicals. The compound is particularly valuable in the synthesis of acrylic compounds and as a monomer in polymerization reactions. Its applications are typically limited to industrial and professional settings due to its hazardous nature.

How to handle prop-2-enenitrile safely?

Prop-2-enenitrile requires strict safety protocols including the use of appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods due to its toxic vapors. Avoid skin contact, inhalation, and ingestion. Keep away from ignition sources as it is highly flammable and ensure emergency procedures are readily available.

How to store prop-2-enenitrile correctly?

Prop-2-enenitrile must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use appropriate chemical storage cabinets designed for flammable liquids and ensure containers are properly sealed and labeled. Store separately from oxidizing agents, acids, and bases to prevent dangerous reactions. Maintain storage temperatures below recommended limits and implement appropriate fire suppression systems.

What to do in case of contact with prop-2-enenitrile?

Immediate action is required for any contact with prop-2-enenitrile. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention. For eye contact, flush with clean water for at least 15 minutes. In case of ingestion, do not induce vomiting and seek immediate medical care.

How to dispose of prop-2-enenitrile properly?

Prop-2-enenitrile must be disposed of as hazardous waste according to local and national regulations. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this substance down drains, sewers, or with regular waste. Ensure proper documentation and manifests are completed for waste tracking. Small quantities may require special collection procedures through authorized disposal services.

How to transport prop-2-enenitrile?

Prop-2-enenitrile is classified as ADR Class 3 (flammable liquids), Packing Group I, indicating it requires the highest level of transport safety measures. Shipments must comply with dangerous goods regulations including proper packaging, labeling, and documentation. Only authorized carriers with dangerous goods certification can transport this substance. Proper shipping papers and emergency response information must accompany all shipments.

Is prop-2-enenitrile subject to specific regulations?

Prop-2-enenitrile is subject to extensive regulatory oversight including REACH registration requirements in Europe and CLP classification as a Category 1B carcinogen. It carries multiple GHS pictograms (GHS02, GHS08, GHS06, GHS05, GHS09) indicating various hazards. The substance requires specific handling authorizations and may be subject to workplace exposure limits and reporting requirements under occupational health regulations.

Where to buy prop-2-enenitrile in Europe?

Prop-2-enenitrile is available through specialized chemical distributors like OYSI, a European distributor of technical chemicals. Due to its hazardous classification, purchase typically requires proper business credentials, safety data sheet acknowledgment, and compliance with regulatory requirements. OYSI can provide technical support and regulatory guidance for European customers requiring this specialized chemical for industrial applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.