Propan-1-ol
C3H8O
propan-1-ol
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Identification
- CAS Number
- 71-23-8
- EC Number
- 200-746-9
- UN Number
- 1274
- Index Number
- 603-003-00-0
- PubChem CID
- 1031
Physical-chemical properties
- Molecular Formula
- C3H8O
- Molar Mass
- 60.10 g/mol
- IUPAC Name
- propan-1-ol
Chemical Identifiers
- InChI
- InChI=1S/C3H8O/c1-2-3-4/h4H,2-3H2,1H3
- InChI Key
- BDERNNFJNOPAEC-UHFFFAOYSA-N
Overview
Propan-1-ol (CAS 71-23-8) is a primary alcohol with three carbon atoms, featuring high solubility and moderate volatility properties. This linear primary alcohol, also known as n-propanol, represents one of the most important lower alcohols in industrial chemistry. With its molecular formula C3H8O and molar mass of 60.1 g/mol, propan-1-ol exhibits excellent miscibility with water and most organic solvents, making it highly versatile for numerous technical applications. The compound appears as a colorless liquid with a characteristic alcoholic odor and demonstrates typical primary alcohol reactivity patterns. From a safety perspective, propan-1-ol is classified as a flammable liquid category 2 and requires careful handling due to its fire hazard potential. The substance can cause serious eye damage and may cause drowsiness or dizziness through inhalation or skin contact, warranting appropriate personal protective equipment during use. Its ADR class 3 classification reflects these flammability concerns for transportation and storage requirements. Industrial applications of propan-1-ol span multiple sectors, with significant use as a solvent in pharmaceutical manufacturing, cosmetics production, and industrial cleaning formulations. The compound serves as an important intermediate in chemical synthesis and finds extensive application in the production of propyl esters and other derivatives. Unlike more complex molecules such as N',N'-diethylpropane-1,3-diamine, propan-1-ol offers straightforward handling characteristics while maintaining excellent solvating properties. In the broader context of alcohol chemistry, propan-1-ol bridges the gap between methanol's high volatility and longer-chain alcohols' reduced solubility, positioning it as an optimal choice for applications requiring balanced physical properties. OYSI provides high-quality propan-1-ol to industrial customers across Europe, ensuring reliable supply for diverse technical applications.
Safety & Classification
Flam. Liq. 2; STOT SE 3; Eye Dam. 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1274 |
| ADR Class | 3 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | n-Propanol |
| Marine Pollutant | No |
Frequently Asked Questions
What is propan-1-ol?
Propan-1-ol is a primary alcohol with the chemical formula C3H8O and CAS number 71-23-8. It is a three-carbon alcohol where the hydroxyl group (-OH) is attached to the terminal carbon atom. With a molecular weight of 60.1 g/mol, propan-1-ol is classified as a flammable liquid and presents hazards including eye damage and specific target organ toxicity. It is widely used as an industrial solvent and chemical intermediate in various applications.
What are the physicochemical properties of propan-1-ol?
Propan-1-ol is a colorless liquid at room temperature with a characteristic alcoholic odor. It has a boiling point of approximately 97°C and is completely miscible with water due to its polar hydroxyl group. The substance also dissolves well in most organic solvents. Its density is lower than water at about 0.804 g/cm³. These properties make it an excellent solvent for both polar and moderately polar compounds in industrial applications.
What is propan-1-ol used for?
Propan-1-ol serves multiple industrial purposes as a solvent for resins, cellulose esters, and various organic compounds. It is used in the production of propyl acetate, pharmaceuticals, and cosmetics. The chemical also functions as a cleaning agent in electronics manufacturing and as an intermediate in organic synthesis. Additionally, it finds applications in printing inks, coatings, and as a coupling agent in formulations requiring both water and oil solubility.
How to handle propan-1-ol safely?
Propan-1-ol requires careful handling due to its flammable nature and potential health hazards. Always wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Keep away from heat sources, sparks, and open flames. Use explosion-proof electrical equipment when working with larger quantities. Ensure proper grounding of containers during transfer operations to prevent static electricity buildup.
How to store propan-1-ol correctly?
Propan-1-ol must be stored in a cool, dry, well-ventilated area away from heat sources and ignition sources. Use original containers or compatible materials such as stainless steel or appropriate plastics. Keep containers tightly closed and properly labeled. Store separately from strong oxidizing agents and acids to prevent dangerous reactions. Ensure storage areas comply with local fire safety regulations for flammable liquids and maintain appropriate fire suppression systems.
What to do in case of contact with propan-1-ol?
Eye contact with propan-1-ol requires immediate and thorough rinsing with clean water for at least 15 minutes while holding eyelids open, followed by urgent medical attention due to potential eye damage. For skin contact, wash thoroughly with soap and water. If inhaled, move the person to fresh air and seek medical attention if respiratory irritation occurs. In case of ingestion, do not induce vomiting and seek immediate medical help. Remove contaminated clothing and wash before reuse.
How to dispose of propan-1-ol appropriately?
Propan-1-ol disposal must comply with local, national, and EU waste regulations as a hazardous chemical waste. Small quantities can be recovered through distillation for reuse when economically viable. Larger quantities should be disposed of through licensed waste management companies specializing in flammable solvents. Never discharge into drains, sewers, or the environment. Contaminated containers must also be treated as hazardous waste and disposed of according to regulatory requirements.
How to transport propan-1-ol?
Propan-1-ol is classified under ADR Class 3 (flammable liquids), Packing Group II, requiring specific transport regulations. Packages must bear appropriate hazard labels including flammable liquid markings and proper shipping names. Transport vehicles need suitable fire extinguishing equipment and emergency response information. Only approved packaging materials meeting UN specifications should be used. Drivers require ADR certification for dangerous goods transport, and route restrictions may apply in certain areas.
Is propan-1-ol subject to specific regulations?
Propan-1-ol is regulated under EU REACH and CLP regulations, requiring registration for quantities above one tonne per year. It is not classified as a Substance of Very High Concern (SVHC). Safety data sheets must be provided to professional users, and proper hazard classification and labeling are mandatory. Industrial users must conduct chemical safety assessments and implement appropriate risk management measures. Workplace exposure limits may apply depending on national regulations in EU member states.
Where to buy propan-1-ol in Europe?
Propan-1-ol is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. OYSI provides high-quality propan-1-ol with complete regulatory documentation including safety data sheets and certificates of analysis. As a professional chemical distributor, OYSI ensures compliance with European regulations and offers technical support for industrial applications. Contact OYSI directly for pricing, availability, and delivery options to your specific European location.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.