Propan-1-ol
C3H8O
propan-1-ol
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Identification
- CAS Number
- 71-23-8
- EC Number
- 200-746-9
- UN Number
- 1274
- Index Number
- 603-003-00-0
- PubChem CID
- 1031
Physical-chemical properties
- Molecular Formula
- C3H8O
- Molar Mass
- 60.10 g/mol
- IUPAC Name
- propan-1-ol
Chemical Identifiers
- InChI
- InChI=1S/C3H8O/c1-2-3-4/h4H,2-3H2,1H3
- InChI Key
- BDERNNFJNOPAEC-UHFFFAOYSA-N
Overview
Propan-1-ol (CAS 71-23-8) is a primary alcohol with three carbon atoms used as solvent and chemical intermediate in industrial applications. Propan-1-ol, also known as 1-propanol or n-propanol, represents a fundamental building block in organic chemistry and industrial processes. This colorless, flammable liquid alcohol exhibits characteristic properties that make it valuable across multiple sectors. With its molecular formula C3H8O and molar mass of 60.1 g/mol, propan-1-ol belongs to the primary alcohol family, where the hydroxyl group is attached to a terminal carbon atom. The substance presents significant safety considerations due to its classification as a flammable liquid category 2 and its potential for causing serious eye damage. The GHS pictograms (GHS02, GHS07, GHS05) indicate flame, exclamation mark, and corrosion hazards respectively, requiring careful handling procedures and appropriate personal protective equipment. Transportation falls under ADR class 3 for flammable liquids, necessitating compliance with specific shipping regulations. Key applications of propan-1-ol include its use as a solvent in cleaning formulations, as an intermediate in pharmaceutical synthesis, and in the production of propyl esters. The chemical industry utilizes this alcohol for manufacturing various derivatives and as a reaction medium. Unlike related compounds such as N',N'-diethylpropane-1,3-diamine which serves primarily in amine chemistry applications, propan-1-ol offers broader solvent capabilities due to its alcohol functionality. Industrial users appreciate propan-1-ol's miscibility with water and many organic solvents, making it particularly suitable for formulation chemistry. Its relatively low toxicity compared to methanol, combined with effective solvating properties, positions it as a preferred choice in many applications. OYSI maintains reliable supply chains for propan-1-ol to meet diverse industrial requirements across European markets.
Safety & Classification
Flam. Liq. 2; STOT SE 3; Eye Dam. 1
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1274 |
| ADR Class | 3 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | n-Propanol |
| Marine Pollutant | No |
Frequently Asked Questions
What is propan-1-ol?
Propan-1-ol is a primary alcohol with the molecular formula C3H8O and CAS number 71-23-8. Also known as 1-propanol or n-propanol, it is a three-carbon straight-chain alcohol with a molecular weight of 60.1 g/mol. This colorless liquid serves as an important industrial solvent and chemical intermediate. Propan-1-ol is classified as a flammable liquid with eye damaging and specific target organ toxicity properties, requiring careful handling in industrial applications.
What are the physicochemical properties of propan-1-ol?
Propan-1-ol is a colorless liquid at room temperature with a characteristic alcoholic odor. It has a boiling point of approximately 97°C and is completely miscible with water and most organic solvents. The substance has a density lower than water and exhibits typical alcohol properties including hydrogen bonding capabilities. Its flammable nature requires storage away from ignition sources, and it readily evaporates at ambient temperatures, contributing to its effectiveness as a solvent.
What is propan-1-ol used for?
Propan-1-ol is widely used as an industrial solvent for resins, cellulose esters, and essential oils. It serves as a chemical intermediate in the production of propyl acetate, propylamine, and other derivatives. The substance finds applications in printing inks, cosmetics, pharmaceuticals, and cleaning formulations. Additionally, it is used in the manufacture of antiseptics and disinfectants, and as a solvent in various extraction processes and chemical syntheses across multiple industries.
How to handle propan-1-ol safely?
Propan-1-ol requires careful handling due to its flammable and eye-damaging properties. Essential personal protective equipment includes safety goggles or face shield, chemical-resistant gloves, and appropriate clothing. Work in well-ventilated areas or use local exhaust ventilation to prevent vapor accumulation. Eliminate all ignition sources including static electricity, sparks, and flames. Handle containers carefully to prevent spills and ensure proper grounding when transferring the substance. Emergency eyewash stations should be readily accessible.
How to store propan-1-ol correctly?
Propan-1-ol must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use appropriate containers made of compatible materials and ensure they are properly sealed to prevent evaporation. Store away from strong oxidizing agents and acids to prevent dangerous reactions. Maintain storage temperatures below the substance's flash point and implement proper fire prevention measures. Storage areas should comply with local fire safety regulations for flammable liquids and include appropriate spill containment measures.
What to do in case of contact with propan-1-ol?
Propan-1-ol contact requires immediate action due to its eye-damaging properties. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek immediate medical attention. In case of skin contact, wash thoroughly with soap and water. If inhaled, move the person to fresh air and monitor for respiratory difficulties. For ingestion, do not induce vomiting and seek medical advice immediately. Remove contaminated clothing and wash before reuse. Always consult emergency services for serious exposures.
How to dispose of propan-1-ol appropriately?
Propan-1-ol disposal must comply with local and national waste regulations as a hazardous waste. The substance cannot be disposed of in regular drains or municipal waste due to its flammable and toxic properties. Contact licensed waste disposal companies for proper collection and treatment. Small quantities may be recovered through distillation for reuse. Contaminated materials including rags and containers must also be treated as hazardous waste. Always consult local environmental authorities for specific disposal requirements and approved facilities.
How to transport propan-1-ol?
Propan-1-ol is classified under ADR as Class 3 (flammable liquids), Packing Group II, indicating moderate danger during transport. Packaging must meet UN specification standards and be properly marked and labeled with appropriate hazard placards. Transport vehicles require proper ventilation and fire extinguishing equipment. Drivers must hold ADR certification for dangerous goods transport. Documentation including transport documents and emergency response information must accompany shipments. Ensure compliance with routing restrictions and quantity limitations for different transport modes.
Is propan-1-ol subject to specific regulations?
Propan-1-ol is subject to multiple European regulations including REACH registration requirements and CLP classification as Flam. Liq. 2, STOT SE 3, and Eye Dam. 1. The substance is not currently listed as an SVHC (Substance of Very High Concern). Workplace exposure limits apply under occupational health regulations. Import/export may require notifications under chemical control laws. Users must comply with safety data sheet requirements and implement appropriate risk management measures. Industrial users should verify compliance with sector-specific regulations and local permit requirements.
Where to buy propan-1-ol in Europe?
Propan-1-ol is available throughout Europe from chemical distributors including OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply chains for industrial customers requiring consistent quality and regulatory compliance. Professional suppliers ensure proper packaging, labeling, and documentation meeting European standards. When selecting a supplier, verify their regulatory compliance, quality certifications, and ability to provide safety data sheets. Contact OYSI for specific availability, technical specifications, and delivery options tailored to your industrial requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.