2-methylpropan-1-ol

C4H10O

CAS78-83-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
78-83-1
EC Number
201-148-0
UN Number
1212
Index Number
603-108-00-1
PubChem CID
6560

Physical-chemical properties

Molecular Formula
C4H10O
Molar Mass
74.12 g/mol
IUPAC Name
2-methylpropan-1-ol

Chemical Identifiers

InChI
InChI=1S/C4H10O/c1-4(2)3-5/h4-5H,3H2,1-2H3
InChI Key
ZXEKIIBDNHEJCQ-UHFFFAOYSA-N

Overview

2-methylpropan-1-ol (CAS 78-83-1) is a branched-chain primary alcohol with characteristic solvent properties and moderate flammability hazards. This four-carbon alcohol, also known as isobutanol, represents an important industrial chemical intermediate with diverse applications across multiple sectors. With its molecular formula C4H10O and molecular weight of 74.12 g/mol, this colorless liquid exhibits typical alcohol functionality while providing unique performance characteristics due to its branched structure. The compound's classification under multiple hazard categories including Flammable Liquid Category 3 and Specific Target Organ Toxicity requires careful handling protocols in industrial environments. The substance displays moderate volatility and excellent solvent properties, making it particularly valuable in coating formulations and chemical synthesis applications. Its branched structure differentiates it from linear alcohols, providing distinct solubility characteristics and reaction profiles. Unlike more complex amine compounds such as N',N'-diethylpropane-1,3-diamine, 2-methylpropan-1-ol offers straightforward alcohol functionality with predictable chemical behavior. Key industrial applications include use as a solvent in paint and coating systems, as an intermediate in ester production, and as a component in cleaning formulations. The chemical industry also employs this alcohol in the manufacture of various derivatives and as a reaction medium for organic synthesis processes. Safety considerations center around its flammable nature (ADR Class 3) and potential for skin and eye irritation, requiring appropriate personal protective equipment and ventilation systems. The GHS pictograms GHS02, GHS07, and GHS05 indicate fire, health, and corrosion hazards respectively. OYSI maintains reliable supply chains for 2-methylpropan-1-ol to support diverse European industrial applications with consistent quality standards.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; STOT SE 3; STOT SE 3; Skin Irrit. 2; Eye Dam. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H335

May cause respiratory irritation.

H336

May cause drowsiness or dizziness.

H315

Causes skin irritation.

H318

Causes serious eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1212
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameIsobutanol
Marine PollutantNo

Frequently Asked Questions

What is 2-methylpropan-1-ol?

2-methylpropan-1-ol is a branched primary alcohol with the molecular formula C4H10O and a molecular weight of 74.12 g/mol. Also known as isobutanol or isobutyl alcohol, it is classified as a flammable liquid category 3 with additional hazards including skin irritation and eye damage. This colorless organic compound belongs to the butanol isomer family and is widely used in industrial applications as a solvent and chemical intermediate.

What are the physicochemical properties of 2-methylpropan-1-ol?

2-methylpropan-1-ol is a colorless liquid at room temperature with a characteristic alcoholic odor. It has moderate solubility in water due to its hydroxyl group while being miscible with most organic solvents. The compound exhibits typical primary alcohol properties with a boiling point around 108°C and a flash point that classifies it as a flammable liquid category 3. Its branched structure makes it less polar than linear butanol isomers.

What is 2-methylpropan-1-ol used for?

2-methylpropan-1-ol serves as an important industrial solvent in paint, coating, and ink formulations due to its excellent dissolving properties. It is used as a chemical intermediate in the synthesis of esters, ethers, and other organic compounds. The substance also finds applications in the production of plasticizers, synthetic resins, and as a component in cleaning agents and degreasers for industrial processes.

How to handle 2-methylpropan-1-ol safely?

2-methylpropan-1-ol requires careful handling due to its flammable nature and irritant properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles or face shield, and appropriate respiratory protection when ventilation is inadequate. Work should be conducted in well-ventilated areas away from ignition sources. Avoid direct skin and eye contact, and ensure proper grounding of equipment to prevent static electricity buildup during transfer operations.

How to store 2-methylpropan-1-ol correctly?

2-methylpropan-1-ol must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Use appropriate containers made of compatible materials and ensure proper labeling according to CLP regulations. Storage areas should be equipped with fire suppression systems and spill containment measures. Keep containers tightly closed when not in use and separate from incompatible materials such as strong oxidizing agents and acids.

What to do in case of contact with 2-methylpropan-1-ol?

2-methylpropan-1-ol contact requires immediate action due to its eye damage and skin irritation potential. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention. In case of skin contact, wash thoroughly with soap and water. If inhaled, move the person to fresh air and monitor for respiratory difficulties. For ingestion, do not induce vomiting and seek immediate medical assistance while providing the safety data sheet.

How to dispose of 2-methylpropan-1-ol appropriately?

2-methylpropan-1-ol disposal must comply with local environmental regulations as it is classified as hazardous waste. The substance should be collected in appropriate containers and transferred to licensed waste disposal facilities for incineration or recovery. Never dispose of it down drains, on soil, or in regular waste streams. Small quantities may be suitable for solvent recovery programs, while larger volumes require professional hazardous waste management services.

How to transport 2-methylpropan-1-ol?

2-methylpropan-1-ol is classified under ADR as Class 3 (flammable liquids), Packing Group III, indicating moderate danger during transport. Packages must bear appropriate hazard labels and comply with ADR packaging requirements for flammable liquids. Transport vehicles require proper documentation, emergency cards, and equipment for spill response. Drivers must hold valid ADR certification, and shipments must follow prescribed routes avoiding populated areas where possible.

Is 2-methylpropan-1-ol subject to specific regulations?

2-methylpropan-1-ol is regulated under European REACH and CLP regulations requiring proper registration, classification, and labeling. It is not currently listed as a Substance of Very High Concern (SVHC), but users must comply with occupational exposure limits and safety requirements. Industrial users may need to implement risk management measures and provide downstream user information. Export/import may require additional documentation depending on destination country regulations.

Where to buy 2-methylpropan-1-ol in Europe?

2-methylpropan-1-ol is available through OYSI, a leading European distributor of technical chemicals serving industrial customers across the continent. OYSI provides this substance with full regulatory compliance documentation, including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures reliable supply chains and technical support for industrial applications requiring 2-methylpropan-1-ol in various quantities and specifications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.