2-methylpropan-1-ol

C4H10O

CAS78-83-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
78-83-1
EC Number
201-148-0
UN Number
1212
Index Number
603-108-00-1
PubChem CID
6560

Physical-chemical properties

Molecular Formula
C4H10O
Molar Mass
74.12 g/mol
IUPAC Name
2-methylpropan-1-ol

Chemical Identifiers

InChI
InChI=1S/C4H10O/c1-4(2)3-5/h4-5H,3H2,1-2H3
InChI Key
ZXEKIIBDNHEJCQ-UHFFFAOYSA-N

Overview

2-methylpropan-1-ol (CAS 78-83-1) is a branched primary alcohol with flammable properties and moderate toxicity characteristics. This four-carbon alcohol, also known by its molecular formula C4H10O, represents an important member of the primary alcohol family used extensively across various industrial applications. With a molecular weight of 74.12 g/mol and EC number 201-148-0, this branched alcohol exhibits distinct physical and chemical properties that make it valuable for specialized industrial processes. The compound presents significant safety considerations, classified under multiple hazard categories including Flammable Liquid Category 3, Specific Target Organ Toxicity Single Exposure Category 3, Skin Irritation Category 2, and Eye Damage Category 1. The "Danger" signal word and associated GHS pictograms (GHS02, GHS07, GHS05) reflect its flammable nature and potential for causing serious eye damage and skin irritation. Transportation regulations classify it under ADR Class 3, requiring appropriate handling protocols for flammable liquids. From an industrial perspective, 2-methylpropan-1-ol serves as an important solvent and chemical intermediate. Its branched structure provides unique solubility characteristics compared to linear alcohols, making it particularly useful in coating formulations, cleaning applications, and as a reaction medium for various chemical processes. The compound also finds application in the production of esters and as a component in specialty chemical manufacturing, where its specific molecular structure offers advantages over related compounds like N-propan-2-ylpropan-2-amine in certain formulations. OYSI maintains reliable supply chains for 2-methylpropan-1-ol, ensuring consistent availability for European industrial customers requiring this specialized alcohol for their technical applications.

Safety & Classification

Danger
Classification:

Flam. Liq. 3; STOT SE 3; STOT SE 3; Skin Irrit. 2; Eye Dam. 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H335

May cause respiratory irritation.

H336

May cause drowsiness or dizziness.

H315

Causes skin irritation.

H318

Causes serious eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1212
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameIsobutanol
Marine PollutantNo

Frequently Asked Questions

What is 2-methylpropan-1-ol?

2-methylpropan-1-ol is a branched primary alcohol with the molecular formula C4H10O and CAS number 78-83-1. Also known as isobutyl alcohol or isobutanol, this colorless liquid has a molecular weight of 74.12 g/mol. It belongs to the group of butanol isomers and is characterized by its branched carbon chain structure. The substance is classified as a flammable liquid and carries multiple hazard classifications including skin irritation and eye damage properties.

What are the physicochemical properties of 2-methylpropan-1-ol?

2-methylpropan-1-ol is a colorless liquid at room temperature with a characteristic alcoholic odor. It has a boiling point of approximately 108°C and a melting point of -108°C. The substance is partially miscible with water and readily soluble in most organic solvents. It has a density of about 0.802 g/cm³ at 20°C and exhibits typical alcohol properties including hydrogen bonding capabilities due to its hydroxyl group.

What is 2-methylpropan-1-ol used for?

2-methylpropan-1-ol is primarily used as a solvent in coatings, paints, and varnishes due to its excellent solvency properties. It serves as an intermediate in the production of esters, ethers, and other chemical compounds. The substance finds applications in the manufacture of plasticizers, synthetic resins, and as a component in cleaning formulations. Additionally, it is used in the pharmaceutical and cosmetic industries as a solvent and processing aid.

How to handle 2-methylpropan-1-ol safely?

2-methylpropan-1-ol requires careful handling due to its flammable nature and irritant properties. Always wear appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Ensure adequate ventilation to prevent vapor accumulation and eliminate ignition sources. Avoid direct skin and eye contact as the substance can cause severe eye damage and skin irritation. Work in well-ventilated areas and use explosion-proof equipment when necessary.

How to store 2-methylpropan-1-ol correctly?

2-methylpropan-1-ol must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Keep containers tightly closed and upright in a designated flammable liquids storage area. Store below 25°C and protect from direct sunlight. Ensure separation from oxidizing agents and incompatible materials. Use appropriate fire suppression systems and maintain proper grounding to prevent static electricity buildup during handling and storage operations.

What to do in case of contact with 2-methylpropan-1-ol?

2-methylpropan-1-ol contact requires immediate action due to its irritant properties. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek immediate medical attention as it can cause severe eye damage. For skin contact, wash thoroughly with soap and water and remove contaminated clothing. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek medical attention promptly.

How to dispose of 2-methylpropan-1-ol properly?

2-methylpropan-1-ol disposal must comply with local and national waste regulations as it is classified as hazardous waste. The substance should be collected and disposed of through licensed waste management companies specializing in flammable liquid waste. Never pour down drains or dispose of with regular waste. Consider recovery and recycling options where possible. Ensure proper labeling of waste containers and maintain documentation of disposal activities as required by environmental regulations.

How to transport 2-methylpropan-1-ol?

2-methylpropan-1-ol is classified under ADR as Class 3 (flammable liquids), Packing Group III. Transportation requires appropriate UN-approved packaging and proper hazardous goods documentation. Vehicles must be equipped with appropriate safety equipment and drivers must hold valid ADR certification. The substance requires proper labeling with flammable liquid placards and hazard identification numbers. Ensure compliance with routing restrictions and emergency response procedures during transport.

Is 2-methylpropan-1-ol subject to specific regulations?

2-methylpropan-1-ol is subject to various European regulations including REACH registration requirements and CLP classification obligations. The substance is not currently listed as a Substance of Very High Concern (SVHC). Manufacturers and importers must comply with REACH registration thresholds and safety data sheet requirements. Users must follow CLP labeling and classification rules, displaying appropriate GHS pictograms (GHS02, GHS07, GHS05) and the signal word 'Danger' on packaging and safety documentation.

Where to buy 2-methylpropan-1-ol in Europe?

2-methylpropan-1-ol is available through OYSI, a leading European distributor of specialty chemicals and industrial raw materials. OYSI provides reliable supply chains across Europe with comprehensive technical support and regulatory compliance documentation. As an established chemical distributor, OYSI ensures product quality, proper packaging, and adherence to all relevant safety and transportation regulations. Contact OYSI directly for specific product grades, quantities, and delivery options to meet your industrial requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.