Propan-1-amine

C3H9N

propan-1-amine

CAS107-10-8

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Identification

CAS Number
107-10-8
EC Number
203-462-3
UN Number
1277
PubChem CID
7852

Physical-chemical properties

Molecular Formula
C3H9N
Molar Mass
59.11 g/mol
IUPAC Name
propan-1-amine

Chemical Identifiers

InChI
InChI=1S/C3H9N/c1-2-3-4/h2-4H2,1H3
InChI Key
WGYKZJWCGVVSQN-UHFFFAOYSA-N

Overview

Propan-1-amine (CAS 107-10-8) is a primary aliphatic amine with high reactivity and strong basic properties. This linear three-carbon primary amine represents one of the fundamental building blocks in organic synthesis and industrial chemistry. With its molecular formula C3H9N and molecular weight of 59.11 g/mol, propan-1-amine exhibits the characteristic properties of primary amines, including strong nucleophilicity and the ability to form hydrogen bonds. The compound appears as a colorless liquid with a characteristic ammonia-like odor and demonstrates complete miscibility with water due to its polar amino group. The chemical reactivity of propan-1-amine stems from its primary amino functionality, making it highly valuable for condensation reactions, acylation processes, and alkylation reactions. Its basic nature, with a pKb similar to other alkylamines, allows it to readily form salts with acids and participate in acid-base equilibria. While sharing some structural similarities with other organic compounds like 2-ethylbutyl acetate in terms of carbon chain length, propan-1-amine's amino functionality provides distinctly different chemical behavior and applications. Safety considerations include its classification under ADR Class 3, indicating flammable properties that require appropriate handling procedures and storage conditions. The compound's volatility and basic nature necessitate proper ventilation and personal protective equipment during handling operations. Industrial applications of propan-1-amine span multiple sectors, including its use as an intermediate in pharmaceutical synthesis, where its reactivity enables the formation of various drug compounds. Additionally, it serves as a precursor in agrochemical manufacturing and finds application in the production of surfactants and corrosion inhibitors. OYSI provides propan-1-amine to meet the demanding requirements of European industrial customers across these diverse application areas.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Transport (ADR)

UN Number1277
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NamePropylamin
Marine PollutantNo

Frequently Asked Questions

What is propan-1-amine?

Propan-1-amine is a primary aliphatic amine with the molecular formula C3H9N and CAS number 107-10-8. It consists of a three-carbon chain with an amino group (-NH2) attached to the terminal carbon. This colorless liquid compound has a molecular weight of 59.11 g/mol and exhibits typical properties of primary amines, including basicity and nucleophilic reactivity.

What are the physicochemical properties of propan-1-amine?

Propan-1-amine is a colorless liquid with a strong, fishy, ammonia-like odor characteristic of primary amines. It has a boiling point of approximately 49°C and is highly soluble in water due to hydrogen bonding between the amino group and water molecules. The compound is also miscible with most organic solvents and has a density lower than water.

What is propan-1-amine used for?

Propan-1-amine serves as an important intermediate in organic synthesis and pharmaceutical manufacturing. It is used in the production of pesticides, herbicides, and various pharmaceutical compounds. The substance also finds applications in the synthesis of surfactants, corrosion inhibitors, and as a building block for more complex amine derivatives in chemical industry processes.

How to handle propan-1-amine safely?

Propan-1-amine requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and adequate ventilation. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation of vapors. Avoid contact with skin and eyes, and ensure proper grounding when transferring the substance to prevent static electricity buildup.

How to store propan-1-amine correctly?

Propan-1-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers away from incompatible materials such as strong acids and oxidizing agents. Storage areas should be equipped with appropriate spill containment measures and maintained at temperatures below the substance's boiling point to prevent excessive vapor formation.

What to do in case of contact with propan-1-amine?

Immediate action is required upon contact with propan-1-amine. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water. In case of eye contact, flush immediately with plenty of water for at least 15 minutes. If inhaled, move the person to fresh air immediately. Seek medical attention if irritation persists or if large amounts were involved.

How to dispose of propan-1-amine appropriately?

Propan-1-amine disposal must comply with local, national, and European waste regulations. The substance should be treated as hazardous chemical waste and disposed of through licensed waste management facilities. Do not discharge into drains, soil, or waterways. Small quantities may be neutralized under controlled conditions by qualified personnel before proper disposal through authorized channels.

How to transport propan-1-amine?

Propan-1-amine is classified under ADR as Class 3 (flammable liquids), Packing Group II, requiring specific transport regulations compliance. Shipments must use appropriate UN-approved packaging and proper labeling with hazard placards. Transport vehicles need proper ventilation and emergency equipment. Only trained personnel should handle transportation, following all applicable dangerous goods transport regulations for road, rail, or sea transport.

Is propan-1-amine subject to specific regulations?

Propan-1-amine is subject to standard European chemical regulations including REACH registration requirements and CLP classification and labeling provisions. While not identified as a Substance of Very High Concern (SVHC), it must comply with general chemical safety regulations. Users must maintain safety data sheets and ensure proper risk assessments are conducted for workplace use and handling.

Where to buy propan-1-amine in Europe?

Propan-1-amine is available through OYSI, a specialized European distributor of technical chemicals serving various industries across Europe. OYSI provides reliable supply chains for professional and industrial customers requiring quality chemical products. Contact OYSI directly for availability, technical specifications, packaging options, and delivery arrangements to your specific European location for your industrial or research applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.