Propan-1-amine

C3H9N

propan-1-amine

CAS107-10-8

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Identification

CAS Number
107-10-8
EC Number
203-462-3
UN Number
1277
PubChem CID
7852

Physical-chemical properties

Molecular Formula
C3H9N
Molar Mass
59.11 g/mol
IUPAC Name
propan-1-amine

Chemical Identifiers

InChI
InChI=1S/C3H9N/c1-2-3-4/h2-4H2,1H3
InChI Key
WGYKZJWCGVVSQN-UHFFFAOYSA-N

Overview

Propan-1-amine (CAS 107-10-8) is a primary aliphatic amine with characteristic ammonia-like odor and high reactivity toward electrophiles. This three-carbon primary amine represents one of the fundamental building blocks in organic synthesis and industrial chemistry. With its molecular formula C3H9N and molecular weight of 59.11 g/mol, propan-1-amine exhibits typical properties of primary amines, including strong basicity and nucleophilicity. The compound appears as a colorless liquid at room temperature, highly soluble in water due to its ability to form hydrogen bonds through the amino group. The chemical structure of propan-1-amine features a straight-chain propyl group attached to an amino group, making it significantly more reactive than its structural analogs. Unlike compounds such as 2-ethylbutyl acetate which serves primarily as a solvent, propan-1-amine acts as a versatile intermediate in chemical synthesis. Its ADR classification as Class 3 indicates flammable properties, requiring appropriate handling procedures and storage conditions to ensure workplace safety. In industrial applications, propan-1-amine serves as a crucial intermediate in pharmaceutical synthesis, particularly in the production of active pharmaceutical ingredients where primary amines are required. The compound also finds extensive use in the manufacture of surfactants and corrosion inhibitors, where its amphiphilic properties prove valuable. Additionally, it functions as a building block in agrochemical production, contributing to the synthesis of various pesticides and herbicides. The versatile nature of propan-1-amine makes it an essential component in numerous chemical processes across multiple industries. Its straightforward synthesis and well-established chemistry ensure consistent availability and quality for industrial users. OYSI provides propan-1-amine to industrial customers across Europe, supporting diverse applications in pharmaceutical, agrochemical, and specialty chemical manufacturing.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Transport (ADR)

UN Number1277
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NamePropylamin
Marine PollutantNo

Frequently Asked Questions

What is propan-1-amine?

Propan-1-amine is a primary aliphatic amine with the molecular formula C3H9N and CAS number 107-10-8. This organic compound consists of a three-carbon chain with an amino group (-NH2) attached to the terminal carbon. With a molecular weight of 59.11 g/mol, propan-1-amine serves as an important building block in organic synthesis and industrial applications.

What are the physicochemical properties of propan-1-amine?

Propan-1-amine is a colorless liquid at room temperature with a characteristic fishy, ammonia-like odor typical of aliphatic amines. It is highly soluble in water due to hydrogen bonding between the amino group and water molecules. The compound is also soluble in most organic solvents including alcohols and ethers, making it versatile for various chemical processes.

What is propan-1-amine used for?

Propan-1-amine is primarily used as an intermediate in pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing. It serves as a building block for creating various organic compounds including pharmaceuticals, pesticides, and corrosion inhibitors. The compound is also utilized in the production of surfactants, rubber chemicals, and as a catalyst in certain polymerization reactions.

How to handle propan-1-amine safely?

Propan-1-amine requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and adequate ventilation. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation of vapors. Avoid contact with skin and eyes, and ensure proper grounding when transferring the material to prevent static discharge due to its flammable nature.

How to store propan-1-amine correctly?

Propan-1-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers away from incompatible materials such as strong acids, oxidizing agents, and reactive metals. Storage areas should be equipped with appropriate fire suppression systems and maintained at temperatures below the compound's flash point.

What to do in case of contact with propan-1-amine?

Propan-1-amine contact requires immediate action: for skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or if significant exposure occurs.

How to dispose of propan-1-amine appropriately?

Propan-1-amine disposal must comply with local and national waste regulations as it is classified as hazardous waste. The compound should never be poured down drains or released into the environment. Contact licensed waste disposal companies for proper treatment, which may include incineration at approved facilities or chemical neutralization. Always consult local environmental authorities for specific disposal requirements.

How to transport propan-1-amine?

Propan-1-amine is classified under ADR Class 3 (flammable liquids), Packing Group II, requiring specific transport protocols. Containers must meet UN specification standards and be properly labeled with appropriate hazard placards. Transport vehicles need proper ventilation and fire suppression equipment. Drivers must hold ADR certification and carry appropriate shipping documents including safety data sheets and emergency response information.

Is propan-1-amine subject to specific regulations?

Propan-1-amine is regulated under REACH regulation in Europe, requiring registration for commercial use. It falls under CLP regulation for classification, labeling, and packaging requirements. The compound is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with workplace exposure limits and maintain safety data sheets as mandated by occupational health and safety regulations.

Where to buy propan-1-amine in Europe?

Propan-1-amine is available through OYSI, a leading European distributor of specialty chemicals serving industrial customers across Europe. OYSI provides reliable supply chains, technical support, and regulatory compliance assistance for propan-1-amine purchases. Contact OYSI directly for availability, packaging options, and delivery arrangements to meet your specific industrial or research requirements throughout the European market.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.