N,N,N',N'-tetramethylethane-1,2-diamine

C6H16N2

CAS110-18-9
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
110-18-9
EC Number
203-744-6
UN Number
2372
Index Number
612-103-00-3
PubChem CID
8037

Physical-chemical properties

Molecular Formula
C6H16N2
Molar Mass
116.20 g/mol
IUPAC Name
N,N,N',N'-tetramethylethane-1,2-diamine

Chemical Identifiers

InChI
InChI=1S/C6H16N2/c1-7(2)5-6-8(3)4/h5-6H2,1-4H3
InChI Key
KWYHDKDOAIKMQN-UHFFFAOYSA-N

Overview

N,N,N',N'-tetramethylethane-1,2-diamine (CAS 110-18-9) is an organic diamine compound with strong basic properties and high reactivity as a chemical intermediate. This versatile tertiary diamine, also known by its molecular formula C6H16N2, serves as an important building block in various chemical synthesis processes. With a molecular weight of 116.2 g/mol, this colorless to pale yellow liquid exhibits significant basicity due to its two tertiary amine functional groups connected by a short ethylene bridge. The compound's structure makes it particularly valuable in applications requiring strong nucleophilic properties or as a catalyst in specific chemical reactions. From a safety perspective, N,N,N',N'-tetramethylethane-1,2-diamine requires careful handling due to its classification as a flammable liquid (Category 2) and skin corrosive substance (Category 1B). The compound also presents acute toxicity risks, necessitating appropriate personal protective equipment and ventilation systems during use. Its ADR Class 3 classification reflects its flammable nature, requiring specialized storage and transportation protocols. The compound finds primary application in polymer chemistry as a curing agent for epoxy resins, where its dual amine functionality provides excellent cross-linking capabilities. It also serves as a catalyst in polyurethane foam production and as an intermediate in pharmaceutical synthesis. In industrial settings, it shares similar applications with related compounds such as N,N-dimethylethanamine, though its diamine structure offers enhanced cross-linking properties. OYSI maintains reliable supply chains for N,N,N',N'-tetramethylethane-1,2-diamine, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H332

Harmful if inhaled.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2372
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping Name1,2-Di-(dimethylamino)-ethan
Marine PollutantNo

Frequently Asked Questions

What is N,N,N',N'-tetramethylethane-1,2-diamine?

N,N,N',N'-tetramethylethane-1,2-diamine is an organic chemical compound with the molecular formula C6H16N2 and CAS number 110-18-9. This diamine derivative has a molecular weight of 116.2 g/mol and belongs to the class of tertiary amines. It is characterized by an ethylene backbone with two dimethylamino groups attached to each carbon atom, making it a symmetrical molecule with strong basic properties due to its nitrogen atoms.

What are the physicochemical properties of N,N,N',N'-tetramethylethane-1,2-diamine?

N,N,N',N'-tetramethylethane-1,2-diamine is a flammable liquid at room temperature with strong basic properties. As a tertiary diamine, it exhibits high water solubility due to its polar nitrogen atoms and can form hydrogen bonds. The compound has a characteristic amine odor and is miscible with many organic solvents. Its basic nature makes it reactive with acids, and it can form stable complexes with metal ions due to its bidentate chelating properties.

What is N,N,N',N'-tetramethylethane-1,2-diamine used for?

N,N,N',N'-tetramethylethane-1,2-diamine is primarily used as a chelating agent and ligand in coordination chemistry applications. It serves as an intermediate in pharmaceutical synthesis, acts as a catalyst or catalyst component in various organic reactions, and functions as a curing agent for epoxy resins. The compound is also utilized in the production of specialty polymers and as a stabilizer in certain chemical formulations, particularly in industrial and research applications.

How to handle N,N,N',N'-tetramethylethane-1,2-diamine safely?

N,N,N',N'-tetramethylethane-1,2-diamine requires careful handling due to its corrosive and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or under fume hoods to avoid inhalation. Keep away from ignition sources due to its flammable nature (Class 2). Use appropriate grounding procedures when transferring the liquid to prevent static electricity buildup.

How to store N,N,N',N'-tetramethylethane-1,2-diamine correctly?

N,N,N',N'-tetramethylethane-1,2-diamine must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers away from incompatible materials such as strong acids and oxidizing agents. Storage areas should be equipped with appropriate fire suppression systems due to the flammable nature of the compound. Ensure containers are properly labeled and stored in secondary containment to prevent environmental release in case of spills.

What to do in case of contact with N,N,N',N'-tetramethylethane-1,2-diamine?

N,N,N',N'-tetramethylethane-1,2-diamine contact requires immediate action due to its corrosive properties. For skin contact, immediately remove contaminated clothing and rinse affected area with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any significant exposure.

How to dispose of N,N,N',N'-tetramethylethane-1,2-diamine appropriately?

N,N,N',N'-tetramethylethane-1,2-diamine disposal must comply with local and national hazardous waste regulations. The compound cannot be disposed of in regular waste streams due to its toxic and corrosive properties. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities may be neutralized under controlled conditions by qualified personnel before disposal. Never discharge into sewers, waterways, or soil. Maintain proper documentation of disposal activities as required by regulatory authorities.

How to transport N,N,N',N'-tetramethylethane-1,2-diamine?

N,N,N',N'-tetramethylethane-1,2-diamine is classified as ADR Class 3 (flammable liquid), Packing Group II, requiring specific transport regulations. The compound must be packaged in UN-approved containers with proper labeling including GHS pictogrammes (GHS02, GHS07, GHS05) and 'Danger' signal word. Transport vehicles must comply with ADR requirements for Class 3 substances. Proper shipping documentation including safety data sheets must accompany shipments, and drivers must have appropriate hazardous materials training.

Is N,N,N',N'-tetramethylethane-1,2-diamine subject to specific regulations?

N,N,N',N'-tetramethylethane-1,2-diamine is subject to various European chemical regulations including REACH registration requirements and CLP classification as a flammable liquid and corrosive substance. While not currently listed as a Substance of Very High Concern (SVHC), it must comply with standard industrial chemical handling regulations. Users must maintain safety data sheets, implement appropriate risk management measures, and ensure proper classification and labeling according to GHS standards throughout the supply chain.

Where to buy N,N,N',N'-tetramethylethane-1,2-diamine in Europe?

N,N,N',N'-tetramethylethane-1,2-diamine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound to industrial and research customers across Europe with proper documentation including certificates of analysis and safety data sheets. As an established chemical distributor, OYSI ensures compliance with European regulations and maintains appropriate quality standards. Contact OYSI directly for availability, technical specifications, and regulatory documentation for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.