N-propan-2-ylpropan-2-amine
C6H15N
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Identification
- CAS Number
- 108-18-9
- EC Number
- 203-558-5
- UN Number
- 1158
- Index Number
- 612-129-00-5
- PubChem CID
- 7912
Physical-chemical properties
- Molecular Formula
- C6H15N
- Molar Mass
- 101.19 g/mol
- IUPAC Name
- N-propan-2-ylpropan-2-amine
Chemical Identifiers
- InChI
- InChI=1S/C6H15N/c1-5(2)7-6(3)4/h5-7H,1-4H3
- InChI Key
- UAOMVDZJSHZZME-UHFFFAOYSA-N
Overview
N-propan-2-ylpropan-2-amine (CAS 108-18-9) is a secondary aliphatic amine with strong basic properties and significant industrial utility as a chemical intermediate and catalyst. This diisopropylamine compound represents an important member of the secondary amine family, characterized by its two isopropyl groups attached to a central nitrogen atom. With the molecular formula C6H15N and a molecular weight of 101.19 g/mol, this colorless liquid exhibits typical amine characteristics including a distinctive ammonia-like odor and strong basicity. The compound's structure makes it particularly valuable in synthetic chemistry applications where selective reactivity and steric hindrance properties are desired. From a safety perspective, N-propan-2-ylpropan-2-amine requires careful handling due to its classification as a flammable liquid (Category 2) and skin corrosive substance (Category 1B). The compound also presents acute toxicity hazards, necessitating appropriate personal protective equipment and well-ventilated working conditions. Its ADR Class 3 classification reflects its flammable nature, requiring specific transport and storage protocols. Industrial applications include its use as a non-nucleophilic base in organic synthesis, particularly in reactions where strong basicity is required without unwanted side reactions. The compound serves as an important intermediate in pharmaceutical manufacturing and as a catalyst in various chemical processes. Its steric bulk makes it especially useful in situations where selectivity is crucial, differentiating it from simpler amines like N,N-dimethylethanamine or more complex diamines such as N,N,N',N'-tetramethylethane-1,2-diamine. OYSI provides high-quality N-propan-2-ylpropan-2-amine to meet diverse industrial requirements across Europe, supporting applications in specialty chemicals, pharmaceuticals, and advanced materials manufacturing.
Safety & Classification
Flam. Liq. 2; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1158 |
| ADR Class | 3 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | Diisopropylamin |
| Marine Pollutant | No |
Frequently Asked Questions
What is N-propan-2-ylpropan-2-amine?
N-propan-2-ylpropan-2-amine is a tertiary amine compound with the molecular formula C6H15N and CAS number 108-18-9. This organic chemical has a molecular weight of 101.19 g/mol and belongs to the family of aliphatic amines. It is classified as a hazardous substance with flammable, toxic, and corrosive properties, requiring careful handling in industrial applications.
What are the physicochemical properties of N-propan-2-ylpropan-2-amine?
N-propan-2-ylpropan-2-amine is a liquid at room temperature with basic properties typical of tertiary amines. The compound has a molecular formula of C6H15N and a molar mass of 101.19 g/mol. As an amine, it exhibits alkaline characteristics and can form salts with acids. Its structure consists of two isopropyl groups attached to a nitrogen atom, giving it specific solubility and reactivity patterns.
What is N-propan-2-ylpropan-2-amine used for?
N-propan-2-ylpropan-2-amine is primarily used as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. The compound serves as a building block for producing various nitrogen-containing chemicals and can act as a catalyst or reagent in specific chemical reactions. Its tertiary amine structure makes it valuable in applications requiring basic nitrogen functionality, including specialty chemical production and research applications.
How to handle N-propan-2-ylpropan-2-amine safely?
N-propan-2-ylpropan-2-amine requires strict safety measures due to its flammable, toxic, and corrosive nature. Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Handle the substance in well-ventilated areas or under fume extraction systems. Keep away from ignition sources, heat, and incompatible materials. Ensure emergency shower and eyewash facilities are readily accessible during handling operations.
How to store N-propan-2-ylpropan-2-amine correctly?
N-propan-2-ylpropan-2-amine must be stored in a cool, dry, well-ventilated area away from heat sources and ignition points due to its flammable nature (Class 2). Use appropriate chemical-resistant containers and ensure proper labeling with GHS pictogramms (GHS02, GHS07, GHS05). Store separately from acids, oxidizing agents, and other incompatible materials. Implement appropriate fire prevention measures and maintain storage temperatures within recommended ranges.
What to do in case of contact with N-propan-2-ylpropan-2-amine?
N-propan-2-ylpropan-2-amine contact requires immediate action due to its corrosive properties (Skin Corr. 1B). For skin contact, immediately remove contaminated clothing and flush affected areas with plenty of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical care.
How to dispose of N-propan-2-ylpropan-2-amine properly?
N-propan-2-ylpropan-2-amine disposal must comply with local and European waste regulations as a hazardous chemical waste. The substance cannot be disposed of through regular waste streams due to its flammable, toxic, and corrosive properties. Contact authorized hazardous waste disposal companies for proper treatment and disposal. Ensure proper waste classification according to the European Waste Catalogue and maintain disposal documentation for regulatory compliance.
How to transport N-propan-2-ylpropan-2-amine?
N-propan-2-ylpropan-2-amine is classified under ADR Class 3 (flammable liquids), Packing Group II, requiring specialized transport procedures. The substance must be packaged in UN-approved containers with appropriate labeling and documentation. Transport vehicles need proper placarding and emergency equipment. Only trained personnel should handle the transport, and specific routing restrictions may apply. Ensure compliance with international dangerous goods regulations for road, rail, and sea transport.
Is N-propan-2-ylpropan-2-amine subject to specific regulations?
N-propan-2-ylpropan-2-amine is regulated under European REACH and CLP regulations due to its hazardous classification. The substance is not currently listed as a Substance of Very High Concern (SVHC). Companies must comply with registration, evaluation, and authorization requirements under REACH. Safety data sheets must be provided according to CLP regulation, and proper hazard communication including GHS pictograms and danger warnings is mandatory.
Where to buy N-propan-2-ylpropan-2-amine in Europe?
N-propan-2-ylpropan-2-amine is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to industrial customers with proper safety documentation, certificates of analysis, and regulatory compliance support. As a professional chemical distributor, OYSI ensures appropriate packaging, handling, and delivery according to ADR transport requirements. Contact OYSI directly for availability, specifications, and regulatory documentation for your specific application requirements.
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N-propan-2-ylpropan-2-amine is a dangerous good. We support you with labeling, packaging, and transport documentation.
Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.