N,N-dimethylnitrous amide
C2H6N2O
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Identification
- CAS Number
- 62-75-9
- EC Number
- 200-549-8
- UN Number
- 3382
- Index Number
- 612-077-00-3
- PubChem CID
- 6124
Physical-chemical properties
- Molecular Formula
- C2H6N2O
- Molar Mass
- 74.08 g/mol
- IUPAC Name
- N,N-dimethylnitrous amide
Chemical Identifiers
- InChI
- InChI=1S/C2H6N2O/c1-4(2)3-5/h1-2H3
- InChI Key
- UMFJAHHVKNCGLG-UHFFFAOYSA-N
Overview
N,N-dimethylnitrous amide (CAS 62-75-9) is a nitroso compound with significant toxicological properties and specialized industrial applications. This organic chemical compound, also known by its IUPAC name N,N-dimethylnitrous amide, represents a member of the nitroso family characterized by its molecular formula C2H6N2O and molecular weight of 74.08 g/mol. The substance exhibits a complex safety profile that requires careful handling protocols due to its classification under multiple hazard categories, including carcinogenicity (Category 1B), acute toxicity, and specific target organ toxicity with repeated exposure. The compound's chemical structure features a nitroso functional group attached to a dimethylamine moiety, distinguishing it from related substances such as N-methylaniline, which lacks the nitroso group but shares similar amine functionality. This structural characteristic contributes to its unique reactivity profile and industrial utility, while simultaneously necessitating stringent safety measures during storage, handling, and transportation under ADR Class 6.1 regulations. Key safety considerations include its classification with GHS pictograms GHS08 (health hazard), GHS06 (acute toxicity), and GHS09 (environmental hazard), accompanied by the signal word "Danger." These classifications reflect the compound's potential for causing serious health effects and environmental impact, particularly in aquatic systems where it demonstrates chronic toxicity. Industrial applications of N,N-dimethylnitrous amide primarily center around its role as a chemical intermediate in pharmaceutical synthesis, specialized organic transformations, and as a reagent in analytical chemistry procedures. The compound also finds use in research applications where its unique nitroso functionality provides specific reaction pathways not available through conventional reagents. OYSI maintains reliable supply chains for N,N-dimethylnitrous amide, ensuring consistent availability for qualified industrial customers across European markets.
Safety & Classification
Carc. 1B; Acute Tox. 2 *; Acute Tox. 3 *; STOT RE 1; Aquatic Chronic 2
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 3382 |
| ADR Class | 6.1 |
| Packing Group | I |
| Tunnel Code | C/D |
| Proper Shipping Name | Dimethylnitrosamin |
| Marine Pollutant | No |
Frequently Asked Questions
What is N,N-dimethylnitrous amide?
N,N-dimethylnitrous amide is a highly toxic organic chemical compound with the molecular formula C2H6N2O and CAS number 62-75-9. This substance has a molecular weight of 74.08 g/mol and is classified as a Category 1B carcinogen, making it extremely hazardous to human health. It presents significant acute toxicity risks and can cause repeated dose organ toxicity. Due to its severe health hazards, it requires strict handling protocols and regulatory compliance in industrial applications.
What are the physicochemical properties of N,N-dimethylnitrous amide?
N,N-dimethylnitrous amide is an organic compound that typically appears as a yellow liquid at room temperature with a characteristic amine-like odor. The substance has a relatively low molecular weight of 74.08 g/mol and contains nitrogen-oxygen functional groups that contribute to its reactivity. It demonstrates solubility in polar solvents due to its polar nature. The compound's physical properties make it volatile and potentially hazardous through inhalation routes, requiring careful containment during handling.
What is N,N-dimethylnitrous amide used for?
N,N-dimethylnitrous amide is primarily used as a chemical intermediate in pharmaceutical and organic synthesis applications. Its main industrial applications include serving as a reagent in specialized chemical reactions and as a precursor for certain pharmaceutical compounds. Due to its extreme toxicity and carcinogenic properties, its use is heavily restricted and limited to controlled laboratory and industrial environments with stringent safety measures. Professional handling is mandatory for any application involving this substance.
How to handle N,N-dimethylnitrous amide safely?
N,N-dimethylnitrous amide requires maximum protection personal protective equipment including full-face respirators, chemical-resistant gloves, and complete body protection suits. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Direct skin and eye contact must be absolutely avoided due to acute toxicity risks. Only trained personnel should handle this substance, and emergency procedures must be readily available. All handling operations should follow strict protocols due to its carcinogenic and highly toxic nature.
How to store N,N-dimethylnitrous amide correctly?
N,N-dimethylnitrous amide must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources and incompatible materials. Storage areas should be restricted to authorized personnel only due to the substance's carcinogenic properties. The storage location must comply with regulations for Category 1B carcinogens and include appropriate containment measures. Temperature control and protection from light may be necessary to maintain stability and prevent decomposition that could increase hazard levels.
What to do in case of contact with N,N-dimethylnitrous amide?
Immediate action is critical for any contact with N,N-dimethylnitrous amide due to its extreme toxicity. For skin contact, remove contaminated clothing immediately and flush affected areas with copious amounts of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care. Always contact poison control and inform medical personnel about the carcinogenic nature of the substance.
How to dispose of N,N-dimethylnitrous amide appropriately?
N,N-dimethylnitrous amide must be disposed of as hazardous waste through licensed hazardous waste disposal companies due to its carcinogenic and toxic properties. The substance cannot be discharged to sewers, waterways, or regular waste streams due to environmental hazard classification. Disposal must comply with local, national, and European waste regulations including proper labeling and documentation. Incineration at high temperatures in specialized facilities is typically the preferred disposal method under controlled conditions with appropriate emission controls.
How to transport N,N-dimethylnitrous amide?
N,N-dimethylnitrous amide is classified under ADR Class 6.1 (Toxic substances) Packing Group I, indicating maximum transport restrictions for highly toxic materials. Transportation requires specialized packaging meeting UN specifications and proper hazardous goods documentation. Vehicles must display appropriate hazard placards and carry emergency response information. Only certified drivers trained in hazardous materials transport can handle shipments. The substance requires strict chain of custody documentation and compliance with international dangerous goods regulations throughout the transport process.
Is N,N-dimethylnitrous amide subject to specific regulations?
N,N-dimethylnitrous amide is subject to extensive regulatory oversight under REACH, CLP, and other European chemical regulations due to its classification as a Category 1B carcinogen. The substance requires detailed safety data sheets, exposure scenarios, and risk assessments. Import, manufacture, and use may require specific authorizations or be subject to restrictions. Companies handling this substance must maintain detailed records and comply with occupational health and safety regulations. Regular monitoring and reporting to regulatory authorities may be mandatory for commercial users.
Where to buy N,N-dimethylnitrous amide in Europe?
N,N-dimethylnitrous amide is available through specialized chemical distributors like OYSI, which serves the European market with technical-grade chemicals for professional applications. Due to its hazardous nature and regulatory requirements, purchase is typically restricted to qualified industrial users with appropriate safety infrastructure and regulatory compliance. Buyers must provide proper documentation and demonstrate adequate safety measures. OYSI can provide technical support and regulatory guidance for customers requiring this specialized chemical compound for legitimate industrial or research purposes.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.