N,N-dimethylaniline

C8H11N

CAS121-69-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
121-69-7
EC Number
204-493-5
UN Number
2253
Index Number
612-016-00-0
PubChem CID
949

Physical-chemical properties

Molecular Formula
C8H11N
Molar Mass
121.18 g/mol
IUPAC Name
N,N-dimethylaniline

Chemical Identifiers

InChI
InChI=1S/C8H11N/c1-9(2)8-6-4-3-5-7-8/h3-7H,1-2H3
InChI Key
JLTDJTHDQAWBAV-UHFFFAOYSA-N

Overview

N,N-dimethylaniline (CAS 121-69-7) is an aromatic amine compound with dimethylamino substitution used primarily as a chemical intermediate and catalyst. N,N-dimethylaniline represents a significant aromatic tertiary amine in industrial chemistry, characterized by its benzene ring structure with two methyl groups attached to the nitrogen atom. With the molecular formula C8H11N and a molecular weight of 121.18 g/mol, this compound appears as a yellow to brown liquid with a characteristic amine odor. The substance belongs to the same chemical family as N-methylaniline, sharing similar structural properties but with enhanced chemical reactivity due to its tertiary amine configuration. From a safety perspective, N,N-dimethylaniline requires careful handling protocols due to its classification as a Category 2 carcinogen and Category 3 acute toxin. The compound displays the GHS08 health hazard, GHS06 skull and crossbones, and GHS09 environmental pictograms, reflecting its potential health and environmental impacts. Its ADR Class 6.1 classification indicates toxic substance transport requirements, while its Aquatic Chronic 2 designation necessitates environmental protection measures during storage and use. Industrial applications of N,N-dimethylaniline include its use as a catalyst in polyurethane foam production, where it accelerates the reaction between isocyanates and polyols. The compound also serves as an intermediate in dye manufacturing and pharmaceutical synthesis, particularly in the production of methylene blue and other triarylmethane dyes. Additionally, it functions as a curing agent in epoxy resin systems and as a chemical intermediate in the synthesis of various organic compounds. OYSI maintains reliable supply chains for N,N-dimethylaniline, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.

Safety & Classification

Danger
Classification:

Carc. 2; Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2253
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameN,N-Dimethylanilin
Marine PollutantNo

Frequently Asked Questions

What is N,N-dimethylaniline?

N,N-dimethylaniline is an aromatic amine compound with the molecular formula C8H11N and CAS number 121-69-7. This organic chemical has a molecular weight of 121.18 g/mol and belongs to the family of substituted anilines. It is classified as a hazardous substance with carcinogenic properties (Category 2) and acute toxicity. The compound is widely used in industrial applications as an intermediate in chemical synthesis and manufacturing processes.

What are the physicochemical properties of N,N-dimethylaniline?

N,N-dimethylaniline is typically a yellowish to brown liquid at room temperature with a characteristic amine-like odor. The compound has moderate solubility in water and is miscible with most organic solvents including alcohols, ethers, and aromatic hydrocarbons. It has a boiling point around 194°C and a density slightly higher than water. The substance is sensitive to light and air, which can cause discoloration and degradation over time.

What is N,N-dimethylaniline used for?

N,N-dimethylaniline is primarily used as an intermediate in the production of dyes, pharmaceuticals, and other organic chemicals. It serves as a precursor in the synthesis of methylene blue, crystal violet, and other triarylmethane dyes. The compound is also utilized in the manufacture of photographic chemicals, rubber accelerators, and as a catalyst in polymerization reactions. Additionally, it finds applications in analytical chemistry as a reagent for various chemical tests.

How to handle N,N-dimethylaniline safely?

N,N-dimethylaniline requires careful handling due to its acute toxicity and carcinogenic properties. Workers must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact, and never eat, drink, or smoke when handling this substance. Emergency eyewash stations and safety showers should be readily accessible in work areas.

How to store N,N-dimethylaniline correctly?

N,N-dimethylaniline should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers away from incompatible materials such as strong oxidizing agents, acids, and bases. Storage areas should be equipped with appropriate containment measures to prevent spills. The substance should be kept in original labeled containers and stored according to local fire codes and chemical storage regulations.

What to do in case of contact with N,N-dimethylaniline?

In case of skin contact with N,N-dimethylaniline, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If eye contact occurs, flush eyes with clean water for at least 15 minutes while holding eyelids open. If inhaled, move the person to fresh air immediately. If swallowed, do not induce vomiting and seek immediate medical attention. Always consult a physician if exposure occurs, providing the safety data sheet.

How to dispose of N,N-dimethylaniline properly?

N,N-dimethylaniline must be disposed of as hazardous waste according to local and national environmental regulations. The substance cannot be discharged to sewers, waterways, or regular waste streams due to its toxicity and environmental impact. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities may be destroyed by controlled incineration at appropriate high-temperature facilities. Always consult local environmental authorities for specific disposal requirements in your region.

How to transport N,N-dimethylaniline?

N,N-dimethylaniline is classified under ADR as Class 6.1 (toxic substances), Packing Group II, indicating significant transport hazards. The substance must be packaged in UN-approved containers with proper labeling including GHS08, GHS06, and GHS09 pictograms and the 'Danger' signal word. Transport vehicles must carry appropriate emergency equipment and documentation. Only trained personnel should handle transportation, and specific routing restrictions may apply depending on local regulations.

Is N,N-dimethylaniline subject to specific regulations?

N,N-dimethylaniline is subject to comprehensive chemical regulations including REACH registration in Europe and CLP classification requirements. The substance carries multiple hazard classifications including carcinogenicity Category 2, acute toxicity Category 3, and aquatic chronic toxicity Category 2. While not currently listed as an SVHC (Substance of Very High Concern), its carcinogenic properties subject it to strict workplace exposure limits and reporting requirements. Companies must maintain detailed safety data sheets and conduct appropriate risk assessments.

Where to buy N,N-dimethylaniline in Europe?

N,N-dimethylaniline is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical distributor, OYSI provides quality N,N-dimethylaniline with proper documentation, safety data sheets, and regulatory compliance for industrial customers across Europe. The company ensures proper packaging, labeling, and transport according to ADR requirements. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.