N,N-dimethylaniline

C8H11N

CAS121-69-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
121-69-7
EC Number
204-493-5
UN Number
2253
Index Number
612-016-00-0
PubChem CID
949

Physical-chemical properties

Molecular Formula
C8H11N
Molar Mass
121.18 g/mol
IUPAC Name
N,N-dimethylaniline

Chemical Identifiers

InChI
InChI=1S/C8H11N/c1-9(2)8-6-4-3-5-7-8/h3-7H,1-2H3
InChI Key
JLTDJTHDQAWBAV-UHFFFAOYSA-N

Overview

N,N-dimethylaniline (CAS 121-69-7) is an aromatic amine compound with dimethylamino substitution on benzene ring, exhibiting significant toxicological properties. N,N-dimethylaniline represents a crucial intermediate in organic synthesis and industrial chemistry, belonging to the family of substituted anilines. This colorless to pale yellow liquid compound features a characteristic amine odor and demonstrates notable chemical reactivity due to its electron-donating dimethylamino group attached to the benzene ring. The compound's molecular structure, with two methyl groups attached to the nitrogen atom, distinguishes it from simpler aromatic amines like N-methylaniline, providing enhanced stability and specific reactivity patterns. The substance requires careful handling due to its classification as a Category 2 carcinogen and Category 3 acute toxicant across multiple exposure routes. Safety protocols must address its potential for skin absorption, inhalation hazards, and environmental impact, particularly regarding aquatic ecosystems where it exhibits chronic toxicity. The GHS08, GHS06, and GHS09 pictograms reflect these serious health and environmental concerns, necessitating appropriate personal protective equipment and engineering controls during handling and storage. Industrial applications of N,N-dimethylaniline include its use as a chemical intermediate in dye manufacturing, particularly for methylene blue and other triarylmethane dyes. The compound serves as an important building block in pharmaceutical synthesis and acts as a catalyst or promoter in various polymerization reactions. Its role in analytical chemistry as a reagent for detecting nitrites and other compounds further demonstrates its versatility. OYSI maintains reliable supply chains for N,N-dimethylaniline, ensuring consistent availability for European industrial customers requiring this specialized aromatic amine compound.

Safety & Classification

Danger
Classification:

Carc. 2; Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2253
ADR Class6.1
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameN,N-Dimethylanilin
Marine PollutantNo

Frequently Asked Questions

What is N,N-dimethylaniline?

N,N-dimethylaniline is an aromatic amine compound with the molecular formula C8H11N and CAS number 121-69-7. This organic chemical has a molecular weight of 121.18 g/mol and belongs to the family of substituted anilines. It is classified as a hazardous substance with carcinogenic properties (Category 2) and acute toxicity. The compound is widely used in industrial applications as an intermediate in chemical synthesis and manufacturing processes.

What are the physicochemical properties of N,N-dimethylaniline?

N,N-dimethylaniline is typically a yellowish to brown liquid at room temperature with a characteristic amine odor. The compound has a molecular weight of 121.18 g/mol and demonstrates moderate solubility in water while being highly soluble in organic solvents. It exhibits basic properties due to its amine functional group and can form salts with acids. The substance may darken upon exposure to light and air due to oxidation processes.

What is N,N-dimethylaniline used for?

N,N-dimethylaniline serves primarily as an intermediate in the production of dyes, pharmaceuticals, and agrochemicals. It is commonly used in the synthesis of methylene blue and other triarylmethane dyes, as well as in the manufacture of various organic compounds. The substance also finds applications as a catalyst in polymerization reactions and as a curing agent for certain resin systems in industrial processes.

How to handle N,N-dimethylaniline safely?

N,N-dimethylaniline requires strict safety measures due to its carcinogenic and toxic properties. Personnel must wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid direct skin contact and ensure emergency shower and eyewash stations are readily accessible. Handle containers carefully to prevent spills and use appropriate tools for transfer operations.

How to store N,N-dimethylaniline correctly?

N,N-dimethylaniline must be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. The storage area should be equipped with appropriate containment measures to prevent environmental release. Keep away from strong oxidizing agents, acids, and incompatible materials. Containers should be properly labeled and stored in designated areas with restricted access. Regular inspection of storage conditions and container integrity is essential for safe storage.

What to do in case of contact with N,N-dimethylaniline?

Immediate action is required in case of contact with N,N-dimethylaniline. For skin contact, remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move the person to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure incident.

How to dispose of N,N-dimethylaniline properly?

N,N-dimethylaniline must be disposed of as hazardous waste in accordance with local, national, and EU regulations. The substance cannot be discharged into sewers, soil, or water bodies due to its environmental hazard classification (Aquatic Chronic 2). Disposal should only be carried out by licensed waste management companies specializing in hazardous chemical waste. Containers must be properly labeled and segregated from other waste streams. Incineration at high temperatures in authorized facilities is typically the preferred disposal method.

How to transport N,N-dimethylaniline?

N,N-dimethylaniline is classified under ADR transport regulations as Class 6.1 (toxic substances), Packing Group II. Transportation requires appropriate UN-specification packaging and proper hazard labeling with GHS pictograms GHS06, GHS08, and GHS09. Vehicles must carry appropriate emergency equipment and documentation. Only trained personnel should handle the transport, and emergency response procedures must be readily available. The substance requires shipping papers indicating its hazardous nature and proper shipping name.

Is N,N-dimethylaniline subject to specific regulations?

N,N-dimethylaniline is subject to comprehensive EU chemical regulations including REACH registration requirements and CLP classification obligations. The substance is classified with multiple hazard categories including carcinogenicity (Category 2) and acute toxicity, requiring appropriate safety data sheets and hazard communication. While not currently listed as a Substance of Very High Concern (SVHC), its carcinogenic classification means it may be subject to authorization procedures and workplace exposure limits under occupational health regulations.

Where to buy N,N-dimethylaniline in Europe?

N,N-dimethylaniline is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to industrial customers across Europe with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures product quality and handles all necessary transport classifications and safety requirements. Contact OYSI directly for availability, technical specifications, and delivery options to your specific European location.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.