Nitrous oxide

N2O

nitrous oxide

CAS10024-97-2
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
10024-97-2
EC Number
233-032-0
UN Number
1070
Index Number
007-031-00-9
PubChem CID
948

Physical-chemical properties

Molecular Formula
N2O
Molar Mass
44.01 g/mol
IUPAC Name
nitrous oxide

Chemical Identifiers

InChI
InChI=1S/N2O/c1-2-3
InChI Key
GQPLMRYTRLFLPF-UHFFFAOYSA-N

Overview

Nitrous oxide (CAS 10024-97-2) is a colorless inorganic gas with anesthetic properties and significant environmental impact potential. This simple nitrogen compound, with the molecular formula N2O and a molecular weight of 44.013 g/mol, plays important roles across multiple industrial sectors while requiring careful handling due to its classification profile. Nitrous oxide presents unique characteristics that distinguish it from other gaseous compounds, including its oxidizing properties and potential for ozone depletion. The substance carries a Danger signal word under GHS classification, reflecting its reproductive toxicity (Repr. 1B), specific target organ toxicity (STOT SE 3, STOT RE 1), and ozone-depleting potential (Ozone 1). From a safety perspective, nitrous oxide requires specialized storage and handling protocols due to its classification under ADR Class 2 for gases. The associated GHS08 and GHS07 pictograms indicate serious health hazards that necessitate appropriate personal protective equipment and workplace controls. Unlike simpler gaseous compounds such as tetrafluoroethene, nitrous oxide's biological activity adds complexity to its risk assessment and management requirements. Industrial applications for nitrous oxide span several sectors, including its use as an oxidizing agent in chemical synthesis, as a propellant in food-grade applications, and in specialized manufacturing processes where its unique reactivity profile provides distinct advantages. The pharmaceutical and food industries particularly value its specific properties for controlled applications. OYSI maintains comprehensive technical support and regulatory documentation for nitrous oxide, ensuring customers receive complete product information and safety guidance for their specific industrial applications.

Safety & Classification

Danger
Classification:

Repr. 1B; STOT SE 3; STOT RE 1; Ozone 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H336

May cause drowsiness or dizziness.

H372

Causes damage to organs through prolonged or repeated exposure.

H420

Harms public health and the environment by destroying ozone in the upper atmosphere.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Irritant

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1070
ADR Class2
Packing Group
Tunnel CodeC/E
Proper Shipping NameDistickstoffmonoxid, unter Druck verflüssigt
Marine PollutantNo

Frequently Asked Questions

What is nitrous oxide?

Nitrous oxide is a colorless gas with the chemical formula N2O and CAS number 10024-97-2. Also known as laughing gas or dinitrogen monoxide, it has a molecular weight of 44.013 g/mol. This compound is classified as a reproductive toxicant (Repr. 1B), specific target organ toxicant (STOT SE 3 and STOT RE 1), and ozone depleting substance (Ozone 1). It carries the danger signal word and requires GHS08 and GHS07 pictograms on safety labeling.

What are the physicochemical properties of nitrous oxide?

Nitrous oxide is a colorless gas at room temperature with a slightly sweet odor and metallic taste. It has a boiling point of -88.5°C and is moderately soluble in water. The gas is non-flammable but supports combustion by releasing oxygen when heated. It is denser than air with a specific gravity of approximately 1.53. Under pressure, nitrous oxide can be liquefied and is often stored in this form for commercial applications.

What is nitrous oxide used for?

Nitrous oxide is primarily used as an anesthetic and analgesic in medical and dental procedures. Industrial applications include its use as an oxidizing agent in rocket propulsion, as a propellant in aerosol products like whipped cream dispensers, and in semiconductor manufacturing. It also serves as an additive in automotive racing for engine performance enhancement and is used in the food industry as a preservative and packaging gas for extending shelf life.

How to handle nitrous oxide safely?

Nitrous oxide handling requires appropriate personal protective equipment including safety goggles, protective gloves, and adequate ventilation to prevent inhalation. Workers should avoid prolonged exposure due to its reproductive toxicity and target organ effects. Use only in well-ventilated areas or with local exhaust ventilation. Ensure proper training on gas cylinder handling, leak detection procedures, and emergency response. Never expose containers to heat sources or mechanical damage, and always secure cylinders during transport and storage.

How to store nitrous oxide correctly?

Nitrous oxide should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Cylinders must be secured upright and protected from physical damage. Storage areas should have adequate ventilation to prevent accumulation of gas in case of leaks. Keep away from flammable materials and oxidizing agents. Storage temperature should not exceed 50°C. Ensure proper segregation from incompatible substances and maintain clear labeling of all containers with appropriate hazard warnings.

What to do in case of contact with nitrous oxide?

Nitrous oxide exposure primarily occurs through inhalation, which can cause dizziness, euphoria, and oxygen deprivation. If overexposure occurs, immediately move the person to fresh air and keep them at rest. If breathing difficulties persist, provide oxygen and seek immediate medical attention. In case of skin contact with liquid nitrous oxide, treat as frostbite injury - warm affected area gently with lukewarm water and seek medical care. For eye contact, flush with water and consult a physician immediately.

How to dispose of nitrous oxide properly?

Nitrous oxide disposal must comply with local and national environmental regulations due to its ozone-depleting properties. Empty cylinders should be returned to the supplier for proper handling. Never release nitrous oxide directly into the atmosphere. Contact specialized waste management companies for disposal of contaminated materials or expired products. Ensure proper documentation of waste disposal activities. Small quantities may be slowly vented in well-ventilated areas following local regulations, but this should be avoided due to environmental concerns.

How to transport nitrous oxide?

Nitrous oxide is classified as ADR Class 2 dangerous goods for transportation. It must be transported in approved cylinders or containers meeting UN specification requirements. Vehicles must display appropriate hazard placards and carry emergency response information. Drivers require ADR certification for dangerous goods transport. Ensure proper cylinder securing, adequate ventilation in transport vehicles, and compliance with quantity limitations. Emergency equipment including breathing apparatus should be available during transport of significant quantities.

Is nitrous oxide subject to specific regulations?

Nitrous oxide is subject to multiple regulatory frameworks including CLP regulation for classification and labeling, showing GHS08 and GHS07 pictograms with danger signal word. It falls under ADR Class 2 for transport regulations. As an ozone-depleting substance, it's regulated under the Montreal Protocol and EU ozone regulation. REACH registration applies for commercial use. Workplace exposure limits are established in many countries. Medical use requires pharmaceutical licensing, while industrial applications may need environmental permits due to its greenhouse gas properties.

Where to buy nitrous oxide in Europe?

Nitrous oxide is available through OYSI, a European distributor of chemical products, serving various industrial and professional markets across Europe. OYSI can provide technical-grade nitrous oxide in appropriate packaging for different applications. When purchasing, ensure the supplier provides proper safety documentation, certificates of analysis, and complies with relevant transportation regulations. Consider your specific purity requirements, quantity needs, and delivery logistics when selecting a supplier. Professional buyers should verify regulatory compliance for their intended use.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.