Hexan-1-ol

C6H14O

hexan-1-ol

CAS111-27-3
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
111-27-3
EC Number
203-852-3
UN Number
2282
Index Number
603-059-00-6
PubChem CID
8103

Physical-chemical properties

Molecular Formula
C6H14O
Molar Mass
102.17 g/mol
IUPAC Name
hexan-1-ol

Chemical Identifiers

InChI
InChI=1S/C6H14O/c1-2-3-4-5-6-7/h7H,2-6H2,1H3
InChI Key
ZSIAUFGUXNUGDI-UHFFFAOYSA-N

Overview

Hexan-1-ol (CAS 111-27-3) is a primary aliphatic alcohol with a straight six-carbon chain structure and characteristic mild alcoholic odor. This linear primary alcohol, also known by its IUPAC designation hexan-1-ol, represents an important intermediate in various chemical processes and industrial applications. With a molecular formula of C6H14O and molecular weight of 102.17 g/mol, this colorless liquid exhibits typical properties of medium-chain alcohols, including moderate volatility and good solvent characteristics for both polar and non-polar compounds. From a safety perspective, hexan-1-ol is classified under the GHS system with the warning signal word and acute toxicity category 4, requiring standard handling precautions typical of organic solvents. The substance carries ADR transport classification 3, indicating its flammable nature, necessitating appropriate storage and transportation protocols in industrial settings. The compound finds widespread use across multiple industrial sectors, particularly as a chemical intermediate in the synthesis of plasticizers, where its linear structure provides favorable properties for polymer modification. Additionally, hexan-1-ol serves as an effective solvent in various formulation applications, especially in coatings and specialty chemical preparations. Its structural similarity to other alcohols like 2-methylcyclohexan-1-ol makes it valuable in comparative studies and as an alternative in specific applications where linear chain alcohols are preferred over cyclic variants. The controlled reactivity profile of hexan-1-ol, combined with its established industrial track record, makes it a reliable choice for manufacturers requiring consistent quality and performance in their processes. OYSI maintains reliable supply chains for hexan-1-ol to support diverse European industrial requirements with technical-grade specifications.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2282
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameHexanol
Marine PollutantNo

Frequently Asked Questions

What is hexan-1-ol?

Hexan-1-ol is a primary alcohol with the molecular formula C6H14O and CAS number 111-27-3. It belongs to the family of straight-chain alcohols, featuring a six-carbon chain with a hydroxyl group at the terminal position. With a molecular weight of 102.17 g/mol, this organic compound is classified as Acute Tox. 4 under GHS regulations, indicating moderate toxicity concerns that require appropriate handling precautions.

What are the physicochemical properties of hexan-1-ol?

Hexan-1-ol is a colorless liquid at room temperature with a characteristic alcoholic odor. It has limited solubility in water due to its hydrophobic carbon chain, but is miscible with most organic solvents like ethanol and diethyl ether. The compound exhibits typical primary alcohol properties, including the ability to undergo oxidation reactions and form esters. Its relatively long carbon chain gives it higher boiling point and lower volatility compared to shorter alcohols.

What is hexan-1-ol used for?

Hexan-1-ol is primarily used as a solvent in industrial applications and as an intermediate in chemical synthesis. It serves as a building block for the production of esters, ethers, and other organic compounds. The substance finds applications in the manufacture of plasticizers, surfactants, and flavoring agents. It is also utilized in research laboratories and in the formulation of specialty chemicals where a medium-chain primary alcohol is required.

How to handle hexan-1-ol safely?

Safe handling of hexan-1-ol requires wearing appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to minimize inhalation exposure. Avoid contact with skin, eyes, and mucous membranes. Keep away from ignition sources as it is classified under ADR Class 3 (flammable liquid). Emergency eyewash stations and safety showers should be readily accessible.

How to store hexan-1-ol correctly?

Hexan-1-ol should be stored in tightly closed containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. As a Class 3 flammable liquid, it requires storage in appropriate fire-resistant cabinets or areas. Keep containers upright to prevent leakage and avoid storage near strong oxidizing agents. Temperature should be controlled to prevent excessive vapor generation, and storage areas should comply with local fire safety regulations.

What to do in case of contact with hexan-1-ol?

In case of skin contact with hexan-1-ol, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with plenty of clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. If ingested, do not induce vomiting and seek immediate medical attention. Always consult safety data sheets for complete first aid procedures.

How to dispose of hexan-1-ol appropriately?

Hexan-1-ol disposal must comply with local and national waste regulations as it is classified as hazardous waste. The substance should not be poured down drains or disposed of with regular waste. Contact licensed waste disposal companies for proper treatment and disposal. Small quantities may be suitable for solvent recovery programs. Always check local environmental regulations and obtain proper waste disposal codes. Documentation of disposal should be maintained for regulatory compliance.

How to transport hexan-1-ol?

Hexan-1-ol is classified under ADR Class 3, Packing Group III for transportation, indicating it is a flammable liquid with relatively low danger. Transport requires appropriate UN specification packaging and hazard labeling with flammable liquid markings. Vehicles must comply with ADR regulations for Class 3 substances, including proper ventilation and fire safety equipment. Transport documents must include proper shipping names and emergency response information.

Is hexan-1-ol subject to specific regulations?

Hexan-1-ol is subject to standard chemical regulations including REACH registration requirements in Europe and CLP classification as Acute Tox. 4 with Warning signal word and GHS07 pictogram. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits, proper labeling requirements, and safety data sheet provisions. Industrial users should ensure proper risk assessments and implement appropriate risk management measures.

Where to buy hexan-1-ol in Europe?

Hexan-1-ol is available through OYSI, a European distributor of technical chemicals, serving customers across the European market. As a specialized chemical distributor, OYSI can provide hexan-1-ol in various packaging sizes suitable for industrial and research applications. The company ensures proper documentation, safety data sheets, and regulatory compliance for European customers. Contact OYSI directly for availability, specifications, and technical support for your hexan-1-ol requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.