Hexan-1-ol

C6H14O

hexan-1-ol

CAS111-27-3
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
111-27-3
EC Number
203-852-3
UN Number
2282
Index Number
603-059-00-6
PubChem CID
8103

Physical-chemical properties

Molecular Formula
C6H14O
Molar Mass
102.17 g/mol
IUPAC Name
hexan-1-ol

Chemical Identifiers

InChI
InChI=1S/C6H14O/c1-2-3-4-5-6-7/h7H,2-6H2,1H3
InChI Key
ZSIAUFGUXNUGDI-UHFFFAOYSA-N

Overview

Hexan-1-ol (CAS 111-27-3) is a primary alcohol with a six-carbon chain structure, exhibiting moderate toxicity and flammable properties. Hexan-1-ol, also known by its IUPAC designation hexan-1-ol, represents a straight-chain primary alcohol widely utilized across various industrial applications. With the molecular formula C6H14O and a molecular weight of 102.17 g/mol, this colorless liquid compound belongs to the family of fatty alcohols and serves as an important intermediate in chemical synthesis processes. From a safety perspective, hexan-1-ol carries an Acute Toxicity Category 4 classification with a Warning signal word and GHS07 pictogram, indicating moderate health hazards that require appropriate handling precautions. As a Class 3 ADR substance, it presents flammability risks during transport and storage, necessitating proper fire prevention measures in industrial environments. The compound's vapor can cause irritation to respiratory systems and skin contact should be minimized through standard personal protective equipment. Industrial applications of hexan-1-ol span multiple sectors, particularly in the production of plasticizers, surfactants, and flavoring agents. The chemical industry frequently employs it as a solvent and extraction medium, while the cosmetics sector utilizes it in formulation processes. Unlike shorter-chain alcohols such as ethane-1,2-diol, hexan-1-ol provides enhanced hydrophobic properties that make it valuable in specialized applications requiring longer carbon chains. The compound's structural similarity to other cyclic alcohols like 2-methylcyclohexan-1-ol makes it an important building block for comparative synthesis studies and alternative pathway development in organic chemistry. OYSI maintains reliable supply chains for hexan-1-ol to support diverse industrial requirements across European markets.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2282
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping NameHexanol
Marine PollutantNo

Frequently Asked Questions

What is hexan-1-ol?

Hexan-1-ol is a primary alcohol with the chemical formula C6H14O and CAS number 111-27-3. It belongs to the family of linear alcohols, featuring a six-carbon chain with a hydroxyl group at the terminal position. With a molecular weight of 102.17 g/mol, hexan-1-ol is classified as Acute Tox. 4 under GHS classification, requiring careful handling in industrial applications.

What are the physicochemical properties of hexan-1-ol?

Hexan-1-ol is a colorless liquid at room temperature with a characteristic alcoholic odor. It has limited solubility in water due to its hydrophobic carbon chain, but is miscible with most organic solvents including ethanol, ether, and chloroform. The compound exhibits typical primary alcohol properties, including the ability to undergo oxidation and esterification reactions.

What is hexan-1-ol used for?

Hexan-1-ol serves as a chemical intermediate in the production of plasticizers, lubricants, and surfactants. It is widely used in the manufacture of hexyl esters, which are employed in flavoring and fragrance industries. Additionally, it functions as a solvent in various industrial processes and as a raw material for producing other chemical compounds in pharmaceutical and cosmetic applications.

How to handle hexan-1-ol safely?

Hexan-1-ol requires standard protective equipment including chemical-resistant gloves, safety glasses, and protective clothing due to its Acute Tox. 4 classification. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid contact with skin and eyes, and ensure proper grounding when transferring the material to prevent static electricity buildup.

How to store hexan-1-ol correctly?

Hexan-1-ol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition sources. Keep containers away from incompatible materials such as strong oxidizing agents and acids. Storage areas should be equipped with appropriate spill containment measures and maintained at temperatures below 25°C to ensure product stability and safety.

What to do in case of contact with hexan-1-ol?

In case of skin contact with hexan-1-ol, immediately wash the affected area with plenty of soap and water for at least 15 minutes. For eye contact, rinse thoroughly with clean water for 15 minutes and seek medical attention. If inhaled, move the person to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention.

How to dispose of hexan-1-ol appropriately?

Hexan-1-ol must be disposed of in accordance with local, national, and international waste regulations as a hazardous chemical waste. The material should not be released into drains, soil, or waterways. Contact licensed waste disposal companies for proper treatment and disposal. Small quantities may be incinerated in approved facilities with appropriate emission controls and temperature monitoring.

How to transport hexan-1-ol?

Hexan-1-ol is classified as ADR Class 3 (flammable liquids), Packing Group III for transportation purposes. It must be shipped in UN-approved packaging with proper labeling including the GHS07 pictogram and 'Warning' signal word. Transport vehicles must comply with ADR regulations for Class 3 substances, including appropriate placarding and driver certification requirements.

Is hexan-1-ol subject to specific regulations?

Hexan-1-ol is regulated under REACH and CLP regulations in Europe, requiring proper classification and labeling as Acute Tox. 4 with Warning signal word and GHS07 pictogram. It is not identified as a Substance of Very High Concern (SVHC). Companies must ensure compliance with safety data sheet requirements and may need to register the substance depending on import/manufacture volumes.

Where to buy hexan-1-ol in Europe?

Hexan-1-ol is available through OYSI, a European distributor of technical chemicals, serving customers across the European market. OYSI provides quality chemical products with proper documentation including certificates of analysis and safety data sheets. Contact OYSI directly for pricing, availability, and technical support regarding hexan-1-ol procurement for your industrial applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.