Ethane-1,2-diol

C2H6O2

ethane-1,2-diol

CAS107-21-1
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
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Identification

CAS Number
107-21-1
EC Number
203-473-3
UN Number
Index Number
603-027-00-1
PubChem CID
174

Physical-chemical properties

Molecular Formula
C2H6O2
Molar Mass
62.07 g/mol
IUPAC Name
ethane-1,2-diol

Chemical Identifiers

InChI
InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI Key
LYCAIKOWRPUZTN-UHFFFAOYSA-N

Overview

Ethane-1,2-diol (CAS 107-21-1) is a vicinal diol with hygroscopic properties and excellent solvent capabilities. This colorless, viscous liquid, commonly known as ethylene glycol, represents one of the most commercially significant diols in industrial chemistry. With its molecular formula C2H6O2 and molecular weight of 62.07 g/mol, ethane-1,2-diol exhibits exceptional miscibility with water and many organic solvents due to its two hydroxyl groups. The compound's unique chemical structure allows it to form strong hydrogen bonds, resulting in a relatively high boiling point of 197°C and excellent thermal stability under normal conditions. From a safety perspective, ethane-1,2-diol carries an Acute Tox. 4 classification with GHS07 pictogram and "Warning" signal word, requiring appropriate handling precautions in industrial environments. Despite its relatively low acute toxicity compared to other glycols, proper ventilation and personal protective equipment remain essential during processing and application. The compound finds extensive use across multiple industrial sectors. Its primary application lies in antifreeze and coolant formulations for automotive and HVAC systems, where its freezing point depression properties prove invaluable. Additionally, ethane-1,2-diol serves as a crucial intermediate in polyester production, particularly polyethylene terephthalate (PET), and functions effectively as a humectant in various formulations. Unlike simpler alcohols such as hexan-1-ol, the diol structure provides superior performance in applications requiring both solubility and thermal stability. OYSI maintains reliable supplies of high-quality ethane-1,2-diol to support diverse industrial applications across European markets, ensuring consistent availability for manufacturers requiring this versatile chemical intermediate.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Frequently Asked Questions

What is ethane-1,2-diol?

Ethane-1,2-diol is a simple organic compound with the molecular formula C2H6O2 and CAS number 107-21-1. Also known as ethylene glycol, it belongs to the diol family with two hydroxyl groups attached to adjacent carbon atoms. This colorless, viscous liquid has a molecular weight of 62.07 g/mol and is classified as Acute Tox. 4 under GHS regulations, requiring careful handling due to its moderate toxicity profile.

What are the physicochemical properties of ethane-1,2-diol?

Ethane-1,2-diol is a colorless, odorless, viscous liquid at room temperature with excellent water solubility due to its two hydroxyl groups. It exhibits hygroscopic properties, readily absorbing moisture from air. The compound has a relatively high boiling point and low vapor pressure, making it stable under normal conditions. Its molecular structure (C2H6O2) with adjacent hydroxyl groups gives it unique chemical reactivity and physical characteristics ideal for various industrial applications.

What is ethane-1,2-diol used for?

Ethane-1,2-diol serves primarily as an antifreeze and coolant in automotive and industrial applications due to its ability to lower freezing points. It is extensively used in the production of polyester fibers, resins, and PET bottles. Other applications include brake fluids, de-icing solutions for aircraft, heat transfer fluids, and as a raw material in chemical synthesis. Its hygroscopic properties make it valuable in certain industrial processes requiring moisture control.

How to handle ethane-1,2-diol safely?

Ethane-1,2-diol requires careful handling due to its Acute Tox. 4 classification and GHS07 pictogram warning. Wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Ensure adequate ventilation to minimize vapor exposure. Avoid ingestion, skin contact, and inhalation. Use proper handling techniques to prevent spills and splashing. Keep emergency eyewash stations and safety showers accessible. Follow established safety protocols and ensure personnel are trained in proper handling procedures.

How to store ethane-1,2-diol correctly?

Ethane-1,2-diol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers upright and properly labeled according to GHS requirements with Warning signal word and GHS07 pictogram. Store away from strong oxidizing agents and acids. Maintain storage temperature within recommended ranges and inspect containers regularly for leaks or damage. Ensure storage areas have appropriate spill containment measures and emergency equipment readily available.

What to do in case of contact with ethane-1,2-diol?

In case of skin contact with ethane-1,2-diol, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. If ingested, do not induce vomiting and seek immediate medical attention. Given its Acute Tox. 4 classification, prompt medical evaluation is recommended for any significant exposure incidents.

How to dispose of ethane-1,2-diol appropriately?

Ethane-1,2-diol disposal must comply with local, national, and European waste regulations due to its toxicity classification. Do not discharge into sewers, waterways, or soil without proper treatment. Contact licensed waste disposal companies for collection and treatment. Small quantities may be recoverable through recycling programs. Contaminated containers should be handled as hazardous waste. Maintain proper documentation for waste disposal activities and follow REACH regulation requirements for waste management and reporting.

How to transport ethane-1,2-diol?

Ethane-1,2-diol transport should follow general dangerous goods regulations despite not having a specific ADR classification in the provided data. Use appropriate packaging materials resistant to the chemical and ensure containers are properly sealed and labeled with GHS07 pictogram and Warning signal word. Transport vehicles should be equipped with appropriate emergency equipment. Drivers should be trained in chemical transport safety and emergency response procedures. Maintain proper shipping documentation and emergency contact information during transport.

Is ethane-1,2-diol subject to specific regulations?

Ethane-1,2-diol is regulated under European REACH and CLP regulations, requiring proper classification, labeling, and safety data sheets. It is not listed as a Substance of Very High Concern (SVHC), but its Acute Tox. 4 classification requires compliance with hazardous substance regulations. Companies must ensure proper registration, evaluation, and risk assessment procedures. Workplace exposure limits and safety measures must be implemented according to occupational health regulations and industry-specific guidelines for chemical handling and worker protection.

Where to buy ethane-1,2-diol in Europe?

Ethane-1,2-diol is available through OYSI, a trusted European distributor of technical chemicals, ensuring reliable supply and regulatory compliance across European markets. OYSI provides properly classified and labeled products meeting REACH and CLP requirements, complete with safety documentation and technical support. As an established chemical distributor, OYSI offers consistent quality, appropriate packaging, and logistics solutions for various industrial applications. Contact OYSI directly for specific grades, quantities, and delivery options tailored to your requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.