2-methylpropyl nitrite

C4H9NO2

CAS542-56-3
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
Danger

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Identification

CAS Number
542-56-3
EC Number
208-819-7
UN Number
2351
Index Number
007-017-00-2
PubChem CID
10958

Physical-chemical properties

Molecular Formula
C4H9NO2
Molar Mass
103.12 g/mol
IUPAC Name
2-methylpropyl nitrite

Chemical Identifiers

InChI
InChI=1S/C4H9NO2/c1-4(2)3-7-5-6/h4H,3H2,1-2H3
InChI Key
APNSGVMLAYLYCT-UHFFFAOYSA-N

Overview

2-methylpropyl nitrite (CAS 542-56-3) is an organic nitrite ester characterized by high flammability and significant toxicological hazards including carcinogenic properties. This volatile organic compound belongs to the alkyl nitrite family and exhibits distinctive chemical properties that make it both industrially relevant and requiring careful handling protocols. The substance presents as a flammable liquid with a molecular weight of 103.12 g/mol and formula C4H9NO2, classified under ADR Class 3 for transportation purposes due to its fire hazard potential. The compound's hazard profile includes classification as a Category 1B carcinogen and Category 2 mutagen, necessitating strict workplace safety measures and specialized storage conditions. Its GHS pictograms (GHS02, GHS08, GHS07) reflect the multiple hazard categories including flammability, health hazards, and acute toxicity. The "Danger" signal word emphasizes the severity of potential risks associated with exposure or improper handling. From an industrial perspective, 2-methylpropyl nitrite finds applications in specialized chemical synthesis processes, particularly in organic chemistry where nitrite esters serve as intermediates or reagents. The compound shares certain structural characteristics with other organic compounds like ethylbenzene, though their applications and safety profiles differ significantly. Industrial uses also extend to specific manufacturing processes requiring controlled nitrite ester chemistry. Quality control and regulatory compliance are paramount when working with this substance, given its carcinogenic classification and mutagenic properties. Proper ventilation, personal protective equipment, and adherence to occupational exposure limits are essential for safe handling. OYSI provides 2-methylpropyl nitrite to qualified industrial customers with comprehensive safety documentation and technical support.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Carc. 1B; Muta. 2; Acute Tox. 4 *; Acute Tox. 4 *

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H350

May cause cancer.

H341

Suspected of causing genetic defects.

H332

Harmful if inhaled.

H302

Harmful if swallowed.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2351
ADR Class3
Packing GroupII
Tunnel CodeD/E
Proper Shipping NameIsobutylnitrit
Marine PollutantNo

Frequently Asked Questions

What is 2-methylpropyl nitrite?

2-methylpropyl nitrite is an organic nitrite compound with the molecular formula C4H9NO2 and CAS number 542-56-3. This chemical substance has a molecular weight of 103.12 g/mol and belongs to the alkyl nitrite family. It is classified as a highly hazardous substance due to its carcinogenic, mutagenic, and flammable properties, requiring careful handling and specialized safety measures in industrial applications.

What are the physicochemical properties of 2-methylpropyl nitrite?

2-methylpropyl nitrite is a flammable liquid at room temperature with characteristic properties typical of organic nitrites. As an alkyl nitrite compound, it exhibits volatility and reactivity with various chemical substances. The compound requires careful temperature control and proper ventilation during handling due to its flammable nature (Flam. Liq. 2 classification) and potential vapor formation.

What is 2-methylpropyl nitrite used for?

2-methylpropyl nitrite is primarily used in specialized industrial applications and research settings. Due to its hazardous classification including carcinogenic and mutagenic properties, its applications are strictly regulated and limited to professional use only. The compound may be utilized in specific chemical synthesis processes or analytical applications where its unique chemical properties are required under controlled laboratory conditions.

How to handle 2-methylpropyl nitrite safely?

2-methylpropyl nitrite requires extensive safety precautions including appropriate personal protective equipment such as chemical-resistant gloves, safety goggles, and respiratory protection. Work must be conducted in well-ventilated areas or under fume hoods due to its toxic and carcinogenic properties. Avoid skin contact, inhalation, and ingestion. Keep away from ignition sources due to its flammable nature and ensure emergency procedures are readily available.

How to store 2-methylpropyl nitrite correctly?

2-methylpropyl nitrite must be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames due to its flammable liquid classification. Use appropriate secondary containment and ensure compatibility with storage materials. Keep containers tightly closed and protected from light. Store separately from incompatible substances and ensure access is restricted to authorized personnel only due to its carcinogenic properties.

What to do in case of contact with 2-methylpropyl nitrite?

Immediate action is required for any contact with 2-methylpropyl nitrite. For skin contact, remove contaminated clothing and flush affected area with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately and seek medical attention. For eye contact, rinse thoroughly with water for several minutes. Seek immediate medical attention in all cases of exposure due to the compound's toxic and carcinogenic properties.

How to dispose of 2-methylpropyl nitrite properly?

2-methylpropyl nitrite must be disposed of as hazardous waste according to local and European regulations due to its carcinogenic, mutagenic, and toxic properties. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this substance down drains, in soil, or with regular waste. Ensure proper documentation and follow all applicable waste management regulations including ADR transport requirements for disposal.

How to transport 2-methylpropyl nitrite?

2-methylpropyl nitrite is classified under ADR as Class 3 (flammable liquid), Packing Group II, requiring specialized transport procedures. Packages must comply with ADR regulations for dangerous goods transport, including proper labeling with GHS02, GHS08, and GHS07 pictograms. Transport must be performed by certified carriers with appropriate documentation and emergency response information readily available during transit.

Is 2-methylpropyl nitrite subject to special regulations?

2-methylpropyl nitrite is subject to extensive regulations under European chemical legislation including REACH and CLP regulations due to its hazardous classification. The substance requires safety data sheets, proper labeling with danger signal words, and compliance with occupational exposure limits. Its carcinogenic (1B) and mutagenic (2) classifications may trigger additional restrictions on use, handling, and distribution within the European market.

Where to buy 2-methylpropyl nitrite in Europe?

2-methylpropyl nitrite is available through specialized chemical distributors in Europe, including OYSI, which supplies laboratory and industrial chemicals. Due to its hazardous classification and regulatory requirements, procurement is typically limited to qualified industrial users and research institutions. Proper documentation, safety assessments, and compliance with local regulations are required for purchase and use of this regulated chemical substance.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.