Ethyl carbonochloridate

Ethyl carbonochloridate is an organochlorine compound with the molecular formula C3H5ClO2 and CAS number 541-41-3. This chemical substance has a molecular weight of 108.52 g/mol and belongs to the class of chloroformate esters. It is classified as a highly hazardous material with multiple danger classes including flammable liquid, acute toxicity, and skin corrosion properties, requiring careful handling in industrial applications.

Ethyl carbonochloridate is typically a colorless to pale yellow liquid at room temperature with a pungent, irritating odor. The compound is moisture-sensitive and readily hydrolyzes in the presence of water, releasing hydrogen chloride gas. It has limited solubility in water due to its reactive nature but is soluble in organic solvents. The substance is classified as a flammable liquid category 2 under GHS classification.

Ethyl carbonochloridate is primarily used as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a reagent for introducing ethoxycarbonyl groups in various chemical reactions and is utilized in the production of pharmaceuticals, agrochemicals, and specialty chemicals. The compound is also employed in peptide synthesis and as a coupling agent in organic chemistry applications requiring selective acylation reactions.

Ethyl carbonochloridate requires strict safety protocols due to its corrosive and toxic nature. Personnel must wear full chemical-resistant suits, chemical-resistant gloves, and respiratory protection with supplied air systems. Work should be conducted in well-ventilated areas or under fume hoods. Avoid contact with skin, eyes, and clothing. Emergency eyewash stations and safety showers must be readily accessible during handling operations.

Ethyl carbonochloridate must be stored in a cool, dry, well-ventilated area away from heat sources and ignition sources. The container should be tightly sealed and protected from moisture to prevent hydrolysis. Store separately from water, alcohols, amines, and other nucleophiles. Storage areas should be equipped with appropriate fire suppression systems and maintained at temperatures below 25°C in corrosion-resistant containers.

Ethyl carbonochloridate contact requires immediate emergency response due to its corrosive properties. For skin contact, immediately remove contaminated clothing and flush with copious amounts of water for at least 15 minutes. For eye contact, rinse immediately with water for at least 15 minutes and seek medical attention. If inhaled, move to fresh air immediately. Seek immediate medical attention for all exposures and provide SDS to medical personnel.

Ethyl carbonochloridate disposal must comply with local and international hazardous waste regulations due to its toxic and corrosive classification. The substance should be disposed of through licensed hazardous waste contractors capable of handling toxic and flammable materials. Never discharge to sewers or water bodies. Small quantities may be carefully hydrolyzed under controlled conditions, but this should only be performed by trained professionals following appropriate safety protocols.

Ethyl carbonochloridate is classified under ADR Class 6.1 (toxic substances) Packing Group I, indicating high toxicity requiring strict transport protocols. Shipments must use appropriate dangerous goods packaging, labeling with GHS02, GHS06, and GHS05 pictograms, and proper documentation. Transport vehicles must be equipped for hazardous materials and drivers must have dangerous goods certification. Emergency response information must accompany all shipments.

Ethyl carbonochloridate is subject to comprehensive chemical regulations including REACH registration requirements in Europe and CLP classification as Dangerous. The substance requires safety data sheets, proper labeling with danger signal words, and compliance with occupational exposure limits. While not currently listed as SVHC, its high toxicity classification subjects it to strict handling, storage, and transport regulations under various national and international chemical safety frameworks.

Ethyl carbonochloridate is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous material handling. OYSI provides comprehensive support including regulatory documentation, safety data sheets, and technical guidance for proper handling. As a professional chemical distributor, OYSI ensures compliance with European regulations and provides reliable supply chains for industrial customers requiring this specialized chemical intermediate.