Methyl carbonochloridate

C2H3ClO2

methyl carbonochloridate

CAS79-22-1
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
Danger

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Identification

CAS Number
79-22-1
EC Number
201-187-3
UN Number
1238
Index Number
607-019-00-9
PubChem CID
6586

Physical-chemical properties

Molecular Formula
C2H3ClO2
Molar Mass
94.50 g/mol
IUPAC Name
methyl carbonochloridate

Chemical Identifiers

InChI
InChI=1S/C2H3ClO2/c1-5-2(3)4/h1H3
InChI Key
XMJHPCRAQCTCFT-UHFFFAOYSA-N

Overview

Methyl carbonochloridate (CAS 79-22-1) is a reactive chloroformate ester with high toxicity and corrosive properties used in organic synthesis applications. This highly reactive organic compound, also known by its IUPAC name methyl carbonochloridate, serves as an important intermediate in various chemical manufacturing processes. With a molecular formula of C2H3ClO2 and molecular weight of 94.5 g/mol, this colorless liquid exhibits significant hazardous properties that require careful handling and specialized safety protocols. The compound belongs to the chloroformate family, sharing certain reactive characteristics with other electrophilic reagents used in organic chemistry. The substance presents multiple safety concerns, classified under several GHS hazard categories including flammable liquid, acute toxicity, and skin corrosion properties. Its classification as Acute Tox. 2 and Skin Corr. 1B indicates severe health hazards upon contact or exposure. The compound requires transport under ADR Class 6.1 regulations due to its toxic nature. Safety pictogramms GHS02, GHS06, and GHS05 clearly identify the fire, toxicity, and corrosive hazards associated with handling this material. In industrial applications, methyl carbonochloridate functions primarily as an acylating agent in pharmaceutical synthesis and as a reactive intermediate in the production of specialty chemicals. It also finds use in polymer chemistry for surface modification processes. Unlike related compounds such as 2-(chloromethyl)oxirane, methyl carbonochloridate specifically targets nucleophilic sites through its carbonyl carbon, making it valuable for selective chemical transformations. OYSI provides methyl carbonochloridate to qualified industrial customers throughout Europe, ensuring proper regulatory compliance and technical support for safe handling procedures.

Safety & Classification

Danger
Classification:

Flam. Liq. 2; Acute Tox. 2 *; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H225

Highly flammable liquid and vapour.

H330

Fatal if inhaled.

H312

Harmful in contact with skin.

H302

Harmful if swallowed.

H314

Causes severe skin burns and eye damage.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Fatal

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number1238
ADR Class6.1
Packing GroupI
Tunnel CodeC/D
Proper Shipping NameMethylchlorformiat
Marine PollutantNo

Frequently Asked Questions

What is methyl carbonochloridate?

Methyl carbonochloridate is an organochlorine compound with the molecular formula C2H3ClO2 and CAS number 79-22-1. This chemical substance has a molecular weight of 94.5 g/mol and belongs to the family of chloroformate esters. It is classified as a highly hazardous material due to its flammable, toxic, and corrosive properties, requiring strict safety protocols during handling and storage in industrial applications.

What are the physicochemical properties of methyl carbonochloridate?

Methyl carbonochloridate is a colorless to pale yellow liquid at room temperature with a pungent, irritating odor. It has a molecular weight of 94.5 g/mol and is highly reactive with water, undergoing hydrolysis to form methanol, carbon dioxide, and hydrogen chloride. The compound is soluble in organic solvents but reacts vigorously with moisture, making it sensitive to atmospheric humidity.

What is methyl carbonochloridate used for?

Methyl carbonochloridate is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a reagent for introducing methoxycarbonyl groups into organic molecules and is employed in the production of carbamates, pharmaceuticals, and agrochemicals. Due to its reactive nature, it is exclusively used in controlled industrial environments by trained professionals following strict safety protocols.

How to handle methyl carbonochloridate safely?

Methyl carbonochloridate requires extreme caution due to its corrosive and toxic properties. Personnel must wear full chemical-resistant protective equipment including acid-resistant gloves, chemical goggles, and respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods, away from ignition sources due to its flammable nature. Emergency shower and eyewash stations must be readily accessible during handling operations.

How to store methyl carbonochloridate correctly?

Methyl carbonochloridate must be stored in tightly sealed, corrosion-resistant containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas should be equipped with appropriate containment systems and maintained below 25°C. The substance must be kept away from water, alcohols, amines, and strong bases, as these can cause violent reactions or decomposition.

What to do in case of contact with methyl carbonochloridate?

Immediate decontamination is critical following exposure to methyl carbonochloridate. For skin contact, remove contaminated clothing and flush affected areas with copious amounts of water for at least 15 minutes. In case of eye contact, irrigate eyes immediately with clean water for 15-20 minutes. If inhaled, move the person to fresh air immediately. Seek immediate medical attention for all exposure routes due to the substance's high toxicity.

How to dispose of methyl carbonochloridate appropriately?

Methyl carbonochloridate waste must be disposed of through licensed hazardous waste disposal facilities in accordance with local and European waste regulations. The substance cannot be disposed of through regular waste streams due to its toxic and corrosive properties. Small quantities should be neutralized by trained personnel using appropriate chemical treatment methods before disposal, while larger amounts require professional hazardous waste management services.

How to transport methyl carbonochloridate?

Methyl carbonochloridate is classified under ADR Class 6.1 (Toxic substances) with Packing Group I, indicating high toxicity. Transportation requires specialized packaging meeting UN specifications and proper hazard labeling with GHS02, GHS06, and GHS05 pictograms. Only certified carriers trained in hazardous material transport are authorized to handle shipments, and all transport documentation must comply with European dangerous goods regulations.

Is methyl carbonochloridate subject to specific regulations?

Methyl carbonochloridate is subject to comprehensive European chemical regulations including REACH registration requirements and CLP classification standards. The substance carries multiple hazard classifications including Flam. Liq. 2, Acute Tox. 2, and Skin Corr. 1B, requiring strict compliance with occupational safety standards. While not currently listed as an SVHC, its high toxicity profile means it may be subject to additional regulatory restrictions and monitoring requirements.

Where to buy methyl carbonochloridate in Europe?

Methyl carbonochloridate is available through specialized chemical distributors like OYSI, which supplies industrial chemicals across Europe. Due to its hazardous nature and regulatory requirements, purchases are restricted to qualified industrial users with appropriate handling capabilities. Buyers must demonstrate proper safety protocols, storage facilities, and regulatory compliance before procurement. Contact OYSI's technical sales team for availability and regulatory guidance for your specific application.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.