Ethyl 2-chloroacetate

Ethyl 2-chloroacetate is an organic chemical compound with the molecular formula C4H7ClO2 and CAS number 105-39-5. This ester derivative features a chloroacetate group bonded to an ethyl group, resulting in a molecular weight of 122.55 g/mol. It is classified as a highly toxic substance with acute toxicity properties and environmental hazards, requiring careful handling in industrial applications.

Ethyl 2-chloroacetate is typically a colorless to pale yellow liquid at room temperature with a characteristic pungent odor. The compound has a molecular weight of 122.55 g/mol and contains both ester and chloro functional groups. It is moderately soluble in water and readily soluble in organic solvents like ethanol and ether, making it useful in various synthetic applications.

Ethyl 2-chloroacetate is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a key building block for producing various pharmaceutical compounds, agrochemicals, and fine chemicals. The compound is particularly valuable in the synthesis of amino acid derivatives and heterocyclic compounds due to its reactive chloroacetate functionality.

Ethyl 2-chloroacetate must be handled with extreme caution due to its Acute Tox. 3 classification and Danger signal word. Essential protective equipment includes chemical-resistant gloves, safety goggles, and appropriate respiratory protection. Work should be conducted in well-ventilated areas or under fume hoods. Avoid skin and eye contact, inhalation, and ingestion. Emergency procedures should be readily available.

Ethyl 2-chloroacetate should be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed to prevent moisture absorption and contamination. Store in original labeled containers in a designated chemical storage area with appropriate secondary containment. Maintain storage temperature as recommended by the manufacturer and ensure proper segregation from incompatible substances.

Ethyl 2-chloroacetate exposure requires immediate action due to its high toxicity. For skin contact, immediately remove contaminated clothing and rinse with copious amounts of water for at least 15 minutes. In case of eye contact, flush immediately with water and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical assistance.

Ethyl 2-chloroacetate disposal must comply with local and national hazardous waste regulations due to its toxic and environmentally hazardous properties. The substance cannot be disposed of in regular waste streams or sewers. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small quantities should be collected in appropriate containers and labeled for hazardous waste pickup.

Ethyl 2-chloroacetate is classified under ADR Class 6.1 (toxic substances) Packing Group II, requiring specialized transport procedures. Packages must bear appropriate hazard labels including GHS06 and GHS09 pictograms with the Danger signal word. Transportation requires proper documentation, trained personnel, and compliance with dangerous goods regulations. Only authorized carriers should handle the shipment of this toxic substance.

Ethyl 2-chloroacetate is subject to comprehensive chemical regulations including REACH registration requirements and CLP classification as Acute Tox. 3 with aquatic toxicity. While not listed as an SVHC substance, it must comply with standard chemical safety regulations, worker protection standards, and environmental discharge limits. Proper safety data sheets and risk assessments are mandatory for commercial use.

Ethyl 2-chloroacetate is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI provides quality ethyl 2-chloroacetate with proper documentation, safety data sheets, and regulatory compliance for industrial customers across Europe. Contact OYSI directly for availability, technical specifications, and pricing information for your specific requirements.