Benzene-1,4-diamine
C6H8N2
benzene-1,4-diamine
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Identification
- CAS Number
- 106-50-3
- EC Number
- 203-404-7
- UN Number
- 1673
- Index Number
- 612-028-00-6
- PubChem CID
- 7814
Physical-chemical properties
- Molecular Formula
- C6H8N2
- Molar Mass
- 108.14 g/mol
- IUPAC Name
- benzene-1,4-diamine
Chemical Identifiers
- InChI
- InChI=1S/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H2
- InChI Key
- CBCKQZAAMUWICA-UHFFFAOYSA-N
Overview
Benzene-1,4-diamine (CAS 106-50-3) is an aromatic diamine compound with two amino groups positioned para to each other on a benzene ring. This organic chemical compound, also known by its IUPAC designation benzene-1,4-diamine, represents a fundamental building block in industrial chemistry with the molecular formula C6H8N2 and a molecular weight of 108.14 g/mol. The substance belongs to the aromatic amine family, characterized by its symmetrical structure where two amino functional groups (-NH2) are attached to opposite positions of the benzene ring, creating a para-substitution pattern that influences its reactivity and applications. The compound exhibits significant hazard properties, classified under multiple acute toxicity categories (Acute Tox. 3) and presenting risks including eye irritation, skin sensitization, and aquatic toxicity. Its ADR classification as Class 6.1 indicates it is a toxic substance requiring careful handling protocols. The presence of GHS pictograms GHS06 and GHS09 with the signal word "Danger" emphasizes the need for appropriate safety measures during storage, handling, and transportation. Benzene-1,4-diamine serves critical roles in various industrial applications, particularly in polymer synthesis where it functions as a monomer for producing high-performance materials such as aramid fibers and polyamides. The chemical industry also utilizes this compound in the manufacture of dyes and pigments, leveraging its aromatic amine structure for color development. Additionally, it finds application in the production of antioxidants and rubber chemicals, where its chemical properties contribute to material stabilization and performance enhancement. Related compounds such as N-methylaniline share similar aromatic amine characteristics, though with different substitution patterns affecting their specific industrial applications. OYSI maintains reliable supply chains for benzene-1,4-diamine to support diverse industrial requirements across European markets.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; Eye Irrit. 2; Skin Sens. 1; Aquatic Acute 1; Aqua...
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1673 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | p-Phenylendiamin, fest |
| Marine Pollutant | No |
Frequently Asked Questions
What is benzene-1,4-diamine?
Benzene-1,4-diamine is an aromatic diamine compound with the molecular formula C6H8N2 and CAS number 106-50-3. This organic chemical features two amino groups (-NH2) positioned at opposite ends of a benzene ring in para configuration. With a molecular weight of 108.14 g/mol, it serves as an important intermediate in chemical synthesis and industrial applications, particularly in polymer and dye manufacturing.
What are the physicochemical properties of benzene-1,4-diamine?
Benzene-1,4-diamine is a crystalline solid at room temperature, typically appearing as white to pale yellow crystals or powder. It has moderate solubility in water and polar solvents due to its amino groups, which can form hydrogen bonds. The compound exhibits basic properties due to the presence of two amino groups and can undergo typical aromatic substitution reactions. It may darken upon exposure to air and light.
What is benzene-1,4-diamine used for?
Benzene-1,4-diamine is primarily used as an intermediate in the production of polymers, particularly aramid fibers and polyimides used in high-performance materials. It serves as a key building block in manufacturing dyes, pigments, and pharmaceutical compounds. The chemical is also utilized in the production of antioxidants, corrosion inhibitors, and various specialty chemicals in industrial applications requiring aromatic diamine functionality.
How to handle benzene-1,4-diamine safely?
Benzene-1,4-diamine requires careful handling due to its Acute Tox. 3 classification and skin sensitization properties. Essential protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Avoid direct skin contact and inhalation of dust or vapors. Work in fume hoods when possible, wear long-sleeved clothing, and ensure emergency eyewash and shower facilities are accessible. Regular training on proper handling procedures is essential.
How to store benzene-1,4-diamine correctly?
Benzene-1,4-diamine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers away from incompatible materials such as strong oxidizing agents and acids. Store in original packaging with proper labeling and ensure adequate separation from food, feed, and drinking water. Implement appropriate inventory rotation and maintain storage temperatures below 25°C to prevent degradation.
What to do in case of contact with benzene-1,4-diamine?
Skin contact with benzene-1,4-diamine requires immediate removal of contaminated clothing and thorough washing with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician after any significant exposure, providing the safety data sheet.
How to dispose of benzene-1,4-diamine properly?
Benzene-1,4-diamine waste must be disposed of through licensed hazardous waste contractors in accordance with local and EU regulations. The compound cannot be disposed of in regular waste streams due to its toxicity and environmental hazard classification. Collect waste in appropriate containers, properly labeled with hazard information. Consider recovery or recycling options where feasible, and maintain detailed waste disposal records as required by environmental regulations.
How to transport benzene-1,4-diamine?
Benzene-1,4-diamine is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. It must be packaged in UN-approved containers with appropriate hazard labels and documentation. Transport vehicles require proper placarding and drivers need ADR certification for dangerous goods. Ensure compliance with quantity limitations, routing restrictions, and emergency response procedures. Proper shipping papers and emergency contact information must accompany all shipments.
Is benzene-1,4-diamine subject to specific regulations?
Benzene-1,4-diamine is subject to comprehensive EU regulations including REACH registration requirements and CLP classification as Acute Tox. 3 and Skin Sens. 1. While not currently listed as an SVHC, it requires safety data sheets and proper hazard communication. Industrial users must comply with occupational exposure limits, environmental discharge regulations, and proper waste management protocols. Regular monitoring and risk assessments may be required in workplace settings.
Where to buy benzene-1,4-diamine in Europe?
Benzene-1,4-diamine is available through OYSI, a trusted European distributor of specialty chemicals serving industrial customers across the continent. OYSI provides properly classified and documented chemical products with full regulatory compliance including safety data sheets and certificates of analysis. As a professional chemical distributor, OYSI ensures reliable supply chains and technical support for industrial applications requiring this aromatic diamine intermediate.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.