Acetyl acetate
C4H6O3
acetyl acetate
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Identification
- CAS Number
- 108-24-7
- EC Number
- 203-564-8
- UN Number
- 1715
- Index Number
- 607-008-00-9
- PubChem CID
- 7918
Physical-chemical properties
- Molecular Formula
- C4H6O3
- Molar Mass
- 102.09 g/mol
- IUPAC Name
- acetyl acetate
Chemical Identifiers
- InChI
- InChI=1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3
- InChI Key
- WFDIJRYMOXRFFG-UHFFFAOYSA-N
Overview
Acetyl acetate (CAS 108-24-7) is an organic anhydride compound with reactive acylating properties and characteristic pungent odor. This versatile chemical intermediate, also known by its IUPAC designation as acetyl acetate, belongs to the family of organic acid anhydrides with molecular formula C4H6O3 and molecular weight of 102.09 g/mol. As a clear, colorless liquid, acetyl acetate exhibits high reactivity due to its anhydride functional groups, making it valuable for numerous synthetic applications in industrial chemistry. The compound demonstrates flammable characteristics and requires careful handling protocols due to its corrosive nature and potential health hazards. From a safety perspective, acetyl acetate carries significant hazard classifications including Flammable Liquid Category 3, Acute Toxicity Category 4, and Skin Corrosion Category 1B, warranting the "Danger" signal word and corresponding GHS pictograms for flame, health hazard, and corrosion. Its ADR classification as Class 8 reflects its corrosive transport properties. Proper storage conditions, adequate ventilation, and appropriate personal protective equipment are essential when working with this substance. Industrial applications of acetyl acetate primarily center around its role as an acetylating agent in organic synthesis, pharmaceutical intermediate production, and specialty chemical manufacturing. The compound serves effectively in esterification reactions and as a reagent for introducing acetyl groups into organic molecules. Unlike simpler compounds such as ethane-1,2-diamine, acetyl acetate offers specific anhydride reactivity that proves invaluable in complex synthetic pathways. OYSI maintains reliable supply chains for acetyl acetate, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.
Safety & Classification
Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1715 |
| ADR Class | 8 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | Essigsäureanhydrid |
| Marine Pollutant | No |
Frequently Asked Questions
What is acetyl acetate?
Acetyl acetate is an organic chemical compound with the molecular formula C4H6O3 and CAS number 108-24-7. This substance has a molecular weight of 102.09 g/mol and belongs to the ester family. It is classified as a flammable liquid with corrosive properties and acute toxicity hazards, requiring careful handling in industrial applications.
What are the physicochemical properties of acetyl acetate?
Acetyl acetate is a colorless liquid with a characteristic ester-like odor at room temperature. As an ester compound with molecular formula C4H6O3, it exhibits typical organic solvent properties including flammability and volatility. The substance has moderate polarity, making it miscible with many organic solvents while having limited water solubility.
What is acetyl acetate used for?
Acetyl acetate serves primarily as an intermediate in organic synthesis and chemical manufacturing processes. It is commonly used as a solvent in industrial applications, particularly in the production of pharmaceuticals, agrochemicals, and specialty chemicals. The compound also finds use in laboratory research as a reagent for various chemical reactions and analytical procedures.
How to handle acetyl acetate safely?
Acetyl acetate requires strict safety protocols due to its corrosive and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid contact with skin, eyes, and respiratory system, and keep away from ignition sources due to its flammable nature.
How to store acetyl acetate correctly?
Acetyl acetate must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and ignition points. Storage areas should be equipped with appropriate fire suppression systems and secondary containment. Keep away from incompatible materials such as strong bases, oxidizing agents, and water-reactive substances to prevent dangerous reactions.
What to do in case of contact with acetyl acetate?
Immediate action is required for acetyl acetate exposure due to its corrosive properties. For skin contact, immediately remove contaminated clothing and flush with plenty of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move to fresh air and monitor breathing. Always consult medical professionals for any exposure incident.
How to dispose of acetyl acetate appropriately?
Acetyl acetate disposal must comply with local and national hazardous waste regulations due to its classification as dangerous goods. The substance cannot be disposed of through regular waste streams and requires treatment by licensed hazardous waste disposal facilities. Neutralization or incineration at appropriate temperatures in specialized facilities is typically required, following all applicable environmental protection guidelines.
How to transport acetyl acetate?
Acetyl acetate is classified as ADR Class 8 (corrosive substances), Packing Group II, requiring specialized dangerous goods transportation procedures. Packages must meet UN specification requirements and display appropriate hazard labels including corrosive and flammable liquid markings. Transport documents, emergency response information, and driver training for dangerous goods are mandatory for legal transportation across Europe.
Is acetyl acetate subject to specific regulations?
Acetyl acetate is regulated under multiple European frameworks including CLP regulation for classification and labeling, and REACH regulation for chemical registration and authorization. The substance requires safety data sheets and proper hazard communication due to its Danger signal word classification. It is not currently listed as a Substance of Very High Concern (SVHC) under REACH.
Where to buy acetyl acetate in Europe?
Acetyl acetate is available through OYSI, a leading European distributor of industrial chemicals and laboratory reagents. OYSI provides high-quality acetyl acetate with complete documentation including certificates of analysis and safety data sheets. As a specialized chemical distributor, OYSI ensures compliance with European regulations and offers reliable supply chain solutions for industrial customers across Europe.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.