Acetyl acetate
C4H6O3
acetyl acetate
Consulting for Acetyl acetate
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Identification
- CAS Number
- 108-24-7
- EC Number
- 203-564-8
- UN Number
- 1715
- Index Number
- 607-008-00-9
- PubChem CID
- 7918
Physical-chemical properties
- Molecular Formula
- C4H6O3
- Molar Mass
- 102.09 g/mol
- IUPAC Name
- acetyl acetate
Chemical Identifiers
- InChI
- InChI=1S/C4H6O3/c1-3(5)7-4(2)6/h1-2H3
- InChI Key
- WFDIJRYMOXRFFG-UHFFFAOYSA-N
Overview
Acetyl acetate (CAS 108-24-7) is an organic anhydride compound with reactive acylating properties and high flammability characteristics. Acetyl acetate, also known by its IUPAC name acetyl acetate, is a colorless liquid organic compound with the molecular formula C4H6O3 and a molecular weight of 102.09 g/mol. This anhydride derivative serves as an important intermediate in organic synthesis and industrial chemical processes, particularly valued for its acylating capabilities in various chemical reactions. The compound exhibits significant reactivity due to its anhydride functional group, making it useful in acetylation reactions and as a building block for more complex organic molecules. From a safety perspective, acetyl acetate requires careful handling due to its classification as a flammable liquid (Category 3) and corrosive substance (Skin Corr. 1B). The compound also presents acute toxicity hazards (Category 4), necessitating appropriate personal protective equipment and ventilation systems during use. Its ADR classification as Class 8 indicates its corrosive nature for transportation purposes, requiring specialized packaging and labeling with GHS pictograms including flame, exclamation mark, and corrosion symbols. Industrial applications of acetyl acetate primarily focus on pharmaceutical intermediate synthesis, where its selective acylating properties prove valuable in drug manufacturing processes. The compound also finds use in specialty chemical production and as a reagent in analytical chemistry applications. Unlike simpler compounds such as ethane-1,2-diamine, acetyl acetate's anhydride structure provides unique reactivity patterns that make it particularly suitable for controlled acetylation reactions in fine chemical synthesis. OYSI maintains reliable supply chains for acetyl acetate, ensuring consistent availability for European industrial customers requiring this specialized chemical intermediate.
Safety & Classification
Flam. Liq. 3; Acute Tox. 4 *; Acute Tox. 4 *; Skin Corr. 1B
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
First Aid Actions
- +P302IF ON SKIN:
- +P352Wash with plenty of water.
- +P361Take off immediately all contaminated clothing.
- +P313Get medical advice/attention.
Related hazard statements:
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 1715 |
| ADR Class | 8 |
| Packing Group | II |
| Tunnel Code | D/E |
| Proper Shipping Name | Essigsäureanhydrid |
| Marine Pollutant | No |
Frequently Asked Questions
What is acetyl acetate?
Acetyl acetate is an organic chemical compound with the molecular formula C4H6O3 and CAS number 108-24-7. This substance has a molecular weight of 102.09 g/mol and belongs to the category of acetate esters. It is classified as a hazardous chemical with multiple safety concerns including flammability, acute toxicity, and skin corrosion properties. Acetyl acetate requires careful handling due to its corrosive nature and potential health risks upon exposure.
What are the physicochemical properties of acetyl acetate?
Acetyl acetate is a liquid organic compound with the molecular formula C4H6O3 and a molecular weight of 102.09 g/mol. As an acetate ester, it typically exhibits moderate volatility and solubility characteristics common to this chemical family. The substance is flammable and requires appropriate fire safety precautions. Its exact physical properties such as boiling point, density, and specific appearance may vary depending on purity and storage conditions.
What is acetyl acetate used for?
Acetyl acetate is primarily used as a chemical intermediate in organic synthesis and industrial manufacturing processes. Its applications typically include use as a reagent in pharmaceutical synthesis, production of specialty chemicals, and as a building block for more complex organic compounds. The substance may also find use in research and development activities within the chemical industry, particularly in processes requiring acetylation reactions or ester chemistry.
How to handle acetyl acetate safely?
Acetyl acetate must be handled with extreme caution due to its corrosive and toxic properties. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation. Keep away from heat sources, sparks, and open flames due to its flammable nature. Always have appropriate fire extinguishing equipment readily available.
How to store acetyl acetate correctly?
Acetyl acetate should be stored in a cool, dry, well-ventilated area away from heat sources, ignition sources, and direct sunlight. Use appropriate chemical-resistant containers with tight-fitting lids to prevent contamination and vapor escape. The storage area should be equipped with appropriate fire suppression systems and spill containment measures. Keep separated from incompatible materials such as strong bases, oxidizing agents, and reactive metals to prevent dangerous reactions.
What to do in case of contact with acetyl acetate?
Acetyl acetate contact requires immediate emergency response due to its corrosive properties. For skin contact, immediately remove contaminated clothing and flush the affected area with plenty of water for at least 15 minutes. For eye contact, rinse immediately with water for at least 15 minutes and seek immediate medical attention. If inhaled, move the person to fresh air immediately. In case of ingestion, do not induce vomiting and seek immediate medical attention.
How to dispose of acetyl acetate appropriately?
Acetyl acetate disposal must comply with local and European waste regulations as it is classified as hazardous waste. The substance should never be disposed of down drains or in regular waste streams. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities may require neutralization or chemical treatment before disposal. Always consult local environmental authorities for specific disposal requirements and maintain proper documentation of waste disposal activities.
How to transport acetyl acetate?
Acetyl acetate is classified under ADR regulations as Class 8 (corrosive substances), Packing Group II, indicating significant transport restrictions. Transportation requires appropriate hazardous goods packaging, labeling, and documentation in compliance with European ADR regulations. Only qualified personnel with proper dangerous goods training should handle transportation. Vehicles must display appropriate hazard placards and carry emergency response information. Ensure proper segregation from incompatible materials during transport.
Is acetyl acetate subject to specific regulations?
Acetyl acetate is subject to European chemical regulations including REACH and CLP requirements. The substance is not currently listed as a Substance of Very High Concern (SVHC), but its hazardous classification requires compliance with safety data sheet provisions, labeling requirements, and risk assessment protocols. Industrial users must implement appropriate risk management measures and may need to register uses depending on quantities handled. Always consult current regulatory databases for the most up-to-date requirements.
Where to buy acetyl acetate in Europe?
Acetyl acetate is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI can provide this substance to qualified industrial customers with appropriate handling capabilities and regulatory compliance. Given the hazardous nature of acetyl acetate, purchases typically require verification of proper storage facilities, safety protocols, and intended use applications. Contact OYSI directly for availability, specifications, and regulatory documentation requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.