Benzene-1,4-diamine;dihydrochloride

C6H10Cl2N2

benzene-1,4-diamine;dihydrochloride

CAS624-18-0
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
624-18-0
EC Number
210-834-9
UN Number
2811
Index Number
612-029-00-1
PubChem CID
12205

Physical-chemical properties

Molecular Formula
C6H10Cl2N2
Molar Mass
181.06 g/mol
IUPAC Name
benzene-1,4-diamine;dihydrochloride

Chemical Identifiers

InChI
InChI=1S/C6H8N2.2ClH/c7-5-1-2-6(8)4-3-5;;/h1-4H,7-8H2;2*1H
InChI Key
IYXMNTLBLQNMLM-UHFFFAOYSA-N

Overview

Benzene-1,4-diamine;dihydrochloride (CAS 624-18-0) is an aromatic diamine hydrochloride salt with significant industrial applications and acute toxicity properties. This crystalline compound, also known by its EC number 210-834-9, represents the dihydrochloride form of para-phenylenediamine, offering enhanced stability and solubility compared to its free base counterpart benzene-1,4-diamine. With a molecular formula of C6H10Cl2N2 and molecular weight of 181.06 g/mol, this aromatic diamine derivative plays a crucial role in various chemical manufacturing processes across European industries. The compound exhibits significant safety considerations, classified under acute toxicity category 3 for multiple exposure routes, requiring careful handling protocols. Its hazard profile includes eye irritation potential, skin sensitization properties, and aquatic toxicity, necessitating appropriate personal protective equipment and environmental controls during industrial use. The GHS06 and GHS09 pictograms indicate both acute toxicity and environmental hazards, while its ADR class 6.1 classification governs transportation requirements. Industrial applications primarily center on polymer synthesis, where it serves as a crucial building block for high-performance materials including aramid fibers and specialized resins. The compound finds extensive use in dye intermediate production, contributing to the manufacture of various colorants and pigments. Additionally, it functions as a curing agent in epoxy formulations and as a cross-linking agent in polymer chemistry applications. Related compounds such as N-methylaniline share similar aromatic amine characteristics but differ in their specific reactivity profiles and industrial applications, highlighting the specialized nature of this dihydrochloride salt. OYSI provides reliable access to benzene-1,4-diamine;dihydrochloride for qualified industrial customers throughout Europe, ensuring consistent quality and regulatory compliance for technical applications.

Safety & Classification

Danger
Classification:

Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; Eye Irrit. 2; Skin Sens. 1; Aquatic Acute 1; Aqua...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H331

Toxic if inhaled.

H311

Toxic in contact with skin.

H301

Toxic if swallowed.

H319

Causes serious eye irritation.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Toxic

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Toxic

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2811
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameBenzen-1,4-diamin-dihydrochlorid
Marine PollutantNo

Frequently Asked Questions

What is benzene-1,4-diamine;dihydrochloride?

Benzene-1,4-diamine;dihydrochloride is an organic chemical compound with the molecular formula C6H10Cl2N2 and CAS number 624-18-0. This substance consists of a benzene ring with two amino groups in para position, forming the dihydrochloride salt. With a molecular weight of 181.06 g/mol, it is classified as a toxic substance requiring careful handling due to its acute toxicity and sensitizing properties.

What are the physicochemical properties of benzene-1,4-diamine;dihydrochloride?

Benzene-1,4-diamine;dihydrochloride is a crystalline solid at room temperature with good water solubility due to its ionic nature as a dihydrochloride salt. The compound has a molecular weight of 181.06 g/mol and appears as a white to off-white powder. Its ionic form enhances stability and handling compared to the free base, making it suitable for industrial applications requiring precise dosing.

What is benzene-1,4-diamine;dihydrochloride used for?

Benzene-1,4-diamine;dihydrochloride is primarily used as an intermediate in the production of dyes, polymers, and pharmaceutical compounds. It serves as a key building block in the synthesis of aramid fibers, antioxidants, and various organic chemicals. The compound finds applications in the textile industry for dye manufacturing and in polymer chemistry for producing high-performance materials with enhanced thermal and chemical resistance.

How to handle benzene-1,4-diamine;dihydrochloride safely?

Benzene-1,4-diamine;dihydrochloride requires careful handling due to its Acute Tox. 3 classification and skin sensitizing properties. Personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection must be worn. Work in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact, and ensure emergency eyewash stations and safety showers are readily accessible during handling operations.

How to store benzene-1,4-diamine;dihydrochloride correctly?

Benzene-1,4-diamine;dihydrochloride should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep containers away from heat sources, direct sunlight, and moisture to prevent degradation. Store separately from oxidizing agents and strong acids. Ensure storage areas are equipped with appropriate spill containment measures and maintain temperatures within manufacturer specifications to preserve product stability.

What to do in case of contact with benzene-1,4-diamine;dihydrochloride?

Immediate action is required upon contact with benzene-1,4-diamine;dihydrochloride due to its toxic and irritating properties. For skin contact, remove contaminated clothing and rinse with plenty of water for at least 15 minutes. In case of eye contact, flush immediately with water and seek medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek immediate medical assistance.

How to dispose of benzene-1,4-diamine;dihydrochloride appropriately?

Benzene-1,4-diamine;dihydrochloride must be disposed of according to local and national hazardous waste regulations due to its toxic classification. Contact licensed waste disposal companies specialized in chemical waste management. The substance cannot be disposed of through regular waste streams or sewage systems. Incineration at authorized facilities with appropriate emission controls is typically the preferred disposal method for this type of organic compound.

How to transport benzene-1,4-diamine;dihydrochloride?

Benzene-1,4-diamine;dihydrochloride is classified under ADR Class 6.1 (toxic substances), Packing Group III for transportation purposes. It requires appropriate hazardous goods packaging, labeling with GHS06 and GHS09 pictograms, and proper shipping documentation. Transport must comply with dangerous goods regulations, including driver training requirements and vehicle placarding. Ensure packages are secure and protected from damage during transit to prevent spillage.

Is benzene-1,4-diamine;dihydrochloride subject to specific regulations?

Benzene-1,4-diamine;dihydrochloride is subject to REACH regulation requiring registration for use in the European Union. The substance is classified under CLP regulation with specific hazard classifications including Acute Tox. 3, Eye Irrit. 2, and Skin Sens. 1. While not currently listed as an SVHC, users must comply with safety data sheet requirements, classification and labeling obligations, and workplace exposure limits where established.

Where to buy benzene-1,4-diamine;dihydrochloride in Europe?

Benzene-1,4-diamine;dihydrochloride is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this substance to industrial customers across Europe with proper documentation and regulatory compliance. As a professional chemical distributor, OYSI ensures quality products, appropriate packaging, and technical support for industrial applications requiring this specialized chemical intermediate.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.