Benzene-1,4-diamine;dihydrochloride
C6H10Cl2N2
benzene-1,4-diamine;dihydrochloride
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Identification
- CAS Number
- 624-18-0
- EC Number
- 210-834-9
- UN Number
- 2811
- Index Number
- 612-029-00-1
- PubChem CID
- 12205
Physical-chemical properties
- Molecular Formula
- C6H10Cl2N2
- Molar Mass
- 181.06 g/mol
- IUPAC Name
- benzene-1,4-diamine;dihydrochloride
Chemical Identifiers
- InChI
- InChI=1S/C6H8N2.2ClH/c7-5-1-2-6(8)4-3-5;;/h1-4H,7-8H2;2*1H
- InChI Key
- IYXMNTLBLQNMLM-UHFFFAOYSA-N
Overview
Benzene-1,4-diamine;dihydrochloride (CAS 624-18-0) is an aromatic diamine salt with enhanced solubility and stability properties for industrial applications. This organic compound, also known by its EC number 210-834-9, represents the dihydrochloride salt form of para-phenylenediamine, offering improved handling characteristics compared to the free base benzene-1,4-diamine. With a molecular formula of C6H10Cl2N2 and molecular weight of 181.06 g/mol, this crystalline substance exhibits significantly enhanced water solubility due to its salt formation, making it particularly valuable in aqueous processing applications. The compound belongs to the aromatic diamine family, sharing structural similarities with other industrial intermediates such as phenylhydrazine, though with distinct reactivity patterns due to its para-substitution pattern. Its chemical structure features two amino groups positioned opposite each other on a benzene ring, with the dihydrochloride form providing better stability during storage and transportation. Safety considerations are paramount when handling this material, as it carries multiple hazard classifications including acute toxicity (Class 3), eye irritation, skin sensitization, and aquatic toxicity. The compound requires careful handling protocols and appropriate personal protective equipment, reflected in its GHS06 and GHS09 pictograms and "Danger" signal word. Transportation falls under ADR Class 6.1 due to its toxic properties. Primary industrial applications include use as a chemical intermediate in polymer synthesis, particularly in the production of aramid fibers and high-performance materials. It also serves as a precursor in pharmaceutical manufacturing and specialty chemical synthesis, where its enhanced solubility profile provides processing advantages over the free base form. OYSI maintains reliable supply chains for benzene-1,4-diamine;dihydrochloride to support European industrial customers' specialized chemical requirements.
Safety & Classification
Acute Tox. 3 *; Acute Tox. 3 *; Acute Tox. 3 *; Eye Irrit. 2; Skin Sens. 1; Aquatic Acute 1; Aqua...
GHS Pictograms
HHazard Statements (H-Statements)
Describe the nature and severity of the hazard
Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).
First Aid Measures
Inhalation
Measures if vapours or dust are inhaled
First Aid Actions
- +P304IF INHALED:
- +P340Remove person to fresh air and keep comfortable for breathing.
- +P311Call a POISON CENTER/doctor.
Related hazard statements:
Skin Contact
Measures if substance contacts the skin
Eye Contact
Measures if substance gets into the eyes
First Aid Actions
- +P305IF IN EYES:
- +P351Rinse cautiously with water for several minutes.
- +P338Remove contact lenses, if present and easy to do. Continue rinsing.
- +P313Get medical advice/attention.
Related hazard statements:
Ingestion
Measures if substance is accidentally swallowed
First Aid Actions
- +P301IF SWALLOWED:
- +P330Rinse mouth.
- +P331Do NOT induce vomiting.
- +P310Immediately call a POISON CENTER/doctor.
Related hazard statements:
General Measures
Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)
First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.
Transport (ADR)
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | III |
| Tunnel Code | E |
| Proper Shipping Name | Benzen-1,4-diamin-dihydrochlorid |
| Marine Pollutant | No |
Frequently Asked Questions
What is benzene-1,4-diamine;dihydrochloride?
Benzene-1,4-diamine;dihydrochloride is an organic chemical compound with the molecular formula C6H10Cl2N2 and CAS number 624-18-0. This substance is the dihydrochloride salt form of para-phenylenediamine, featuring two amino groups positioned opposite each other on a benzene ring. With a molecular weight of 181.06 g/mol, it is classified as a hazardous chemical requiring careful handling due to its acute toxicity and sensitizing properties.
What are the physicochemical properties of benzene-1,4-diamine;dihydrochloride?
Benzene-1,4-diamine;dihydrochloride typically appears as a white to off-white crystalline powder at room temperature. As a dihydrochloride salt, it exhibits good water solubility compared to its free base form. The compound has a molecular weight of 181.06 g/mol and contains two chloride ions paired with the diamine base. Its chemical stability and handling characteristics are influenced by the presence of the amino groups and the ionic nature of the salt structure.
What is benzene-1,4-diamine;dihydrochloride used for?
Benzene-1,4-diamine;dihydrochloride is primarily used as an intermediate in chemical synthesis and manufacturing processes. It serves as a building block for the production of dyes, pigments, and various organic compounds. The compound finds applications in pharmaceutical intermediates, polymer chemistry, and specialty chemical manufacturing. Its diamine functionality makes it valuable for creating cross-linked materials and as a curing agent in certain industrial applications.
How to handle benzene-1,4-diamine;dihydrochloride safely?
Benzene-1,4-diamine;dihydrochloride must be handled with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing due to its Acute Tox. 3 classification. Work should be conducted in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact as the substance can cause eye irritation and skin sensitization. Always wash hands thoroughly after handling and ensure emergency eyewash stations are accessible.
How to store benzene-1,4-diamine;dihydrochloride correctly?
Benzene-1,4-diamine;dihydrochloride should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep the substance away from incompatible materials such as strong oxidizing agents and acids. Storage areas should be equipped with appropriate spill containment measures and restricted access. Maintain stable temperature conditions to prevent degradation and ensure containers are properly labeled with hazard information and handling precautions.
What to do in case of contact with benzene-1,4-diamine;dihydrochloride?
In case of skin contact with benzene-1,4-diamine;dihydrochloride, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for at least 15 minutes and seek medical attention. If inhaled, move the person to fresh air and monitor breathing. In case of ingestion, do not induce vomiting and seek immediate medical attention. Always consult a physician if symptoms develop.
How to dispose of benzene-1,4-diamine;dihydrochloride properly?
Benzene-1,4-diamine;dihydrochloride must be disposed of as hazardous waste through licensed waste management facilities in accordance with local and European regulations. The substance cannot be disposed of in regular waste streams due to its toxicity and environmental hazard classification. Collect waste in appropriate containers, properly labeled, and arrange collection by authorized hazardous waste disposal companies. Consult local environmental authorities for specific disposal requirements and approved disposal methods.
How to transport benzene-1,4-diamine;dihydrochloride?
Benzene-1,4-diamine;dihydrochloride is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transport purposes. The substance must be packaged in UN-approved containers with appropriate hazard labels and documentation. Transport vehicles must comply with ADR regulations for toxic substances, including proper placarding and driver certification. Shipping documents must include the correct UN number, proper shipping name, hazard class, and packing group information according to dangerous goods transport regulations.
Is benzene-1,4-diamine;dihydrochloride subject to specific regulations?
Benzene-1,4-diamine;dihydrochloride is subject to European REACH and CLP regulations requiring proper registration, classification, and labeling. The substance carries GHS pictograms GHS06 and GHS09 with the signal word 'Danger' due to its acute toxicity and environmental hazards. It is not currently listed as an SVHC (Substance of Very High Concern). Companies handling this chemical must comply with safety data sheet requirements, worker protection measures, and environmental release reporting where applicable.
Where to buy benzene-1,4-diamine;dihydrochloride in Europe?
Benzene-1,4-diamine;dihydrochloride is available through OYSI, a specialized European distributor of technical chemicals. As a professional chemical supplier, OYSI can provide this substance with proper documentation, safety data sheets, and regulatory compliance support. When sourcing this hazardous chemical, ensure your supplier maintains appropriate quality standards, proper storage conditions, and regulatory compliance. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements.
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Data Sources
Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.