Benzene-1,2-diamine;dihydrochloride

C6H10Cl2N2

benzene-1,2-diamine;dihydrochloride

CAS615-28-1
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS06 Gefahrensymbol: Giftig – Totenkopf mit Knochen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
615-28-1
EC Number
210-418-7
UN Number
2811
Index Number
612-146-00-8
PubChem CID
11990

Physical-chemical properties

Molecular Formula
C6H10Cl2N2
Molar Mass
181.06 g/mol
IUPAC Name
benzene-1,2-diamine;dihydrochloride

Chemical Identifiers

InChI
InChI=1S/C6H8N2.2ClH/c7-5-3-1-2-4-6(5)8;;/h1-4H,7-8H2;2*1H
InChI Key
RIIWUGSYXOBDMC-UHFFFAOYSA-N

Overview

Benzene-1,2-diamine dihydrochloride (CAS 615-28-1) is an aromatic diamine salt with significant industrial applications and notable safety considerations. This crystalline compound, also known by its EC number 210-418-7, represents the dihydrochloride salt form of ortho-phenylenediamine, offering enhanced stability and solubility compared to its free base counterpart. With a molecular formula of C6H10Cl2N2 and molecular weight of 181.06 g/mol, this aromatic diamine derivative belongs to the same chemical family as benzene-1,2-diamine, sharing similar structural characteristics but with modified physical and handling properties due to salt formation. The compound exhibits multiple hazard classifications including carcinogenic (Category 2) and mutagenic (Category 2) properties, requiring careful handling protocols and appropriate safety measures. Its acute toxicity profile spans multiple categories, while also presenting risks for eye irritation and skin sensitization. The presence of GHS08, GHS06, and GHS09 pictograms emphasizes the serious health hazards, acute toxicity risks, and environmental concerns associated with this material. Transportation falls under ADR Class 6.1, reflecting its toxic nature. Primary industrial applications include its use as an intermediate in dye synthesis, particularly in the production of specialized colorants and pigments. The compound also serves as a building block in pharmaceutical intermediates and finds application in polymer chemistry for the synthesis of specialized materials. Its dual amine functionality makes it valuable in cross-linking reactions and as a curing agent in certain resin systems. OYSI maintains availability of benzene-1,2-diamine dihydrochloride for qualified industrial customers with appropriate handling capabilities and regulatory compliance.

Safety & Classification

Danger
Classification:

Carc. 2; Muta. 2; Acute Tox. 4 *; Acute Tox. 4 *; Acute Tox. 3 *; Eye Irrit. 2; Skin Sens. 1; Aqu...

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H341

Suspected of causing genetic defects.

H332

Harmful if inhaled.

H312

Harmful in contact with skin.

H301

Toxic if swallowed.

H319

Causes serious eye irritation.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Toxic

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2811
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping NameBenzen-1,2-diamin-dihydrochlorid
Marine PollutantNo

Frequently Asked Questions

What is benzene-1,2-diamine;dihydrochloride?

Benzene-1,2-diamine;dihydrochloride is an organic chemical compound with the molecular formula C6H10Cl2N2 and CAS number 615-28-1. This substance is the dihydrochloride salt form of ortho-phenylenediamine, featuring two amino groups attached to adjacent carbon atoms on a benzene ring. With a molecular weight of 181.06 g/mol, it is classified as a hazardous substance due to its carcinogenic and mutagenic properties, requiring careful handling and specialized safety measures in industrial applications.

What are the physicochemical properties of benzene-1,2-diamine;dihydrochloride?

Benzene-1,2-diamine;dihydrochloride is a crystalline solid at room temperature with enhanced stability compared to its free base form. The dihydrochloride salt formation improves its water solubility characteristics, making it more suitable for certain industrial applications. As an aromatic diamine derivative, it exhibits typical properties of substituted benzene compounds. The compound's physical appearance and specific solubility parameters depend on purity grade and crystalline form, with the salt form generally showing better handling properties than the free amine.

What is benzene-1,2-diamine;dihydrochloride used for?

Benzene-1,2-diamine;dihydrochloride is primarily used as an intermediate in chemical synthesis, particularly in the production of dyes, pigments, and polymer additives. It serves as a key building block for manufacturing various aromatic compounds and specialty chemicals. The compound finds applications in research and development laboratories for organic synthesis reactions. Due to its hazardous classification, its use is restricted to professional industrial settings with appropriate safety controls and regulatory compliance measures in place.

How to handle benzene-1,2-diamine;dihydrochloride safely?

Benzene-1,2-diamine;dihydrochloride requires strict safety protocols due to its carcinogenic and mutagenic properties (Carc. 2, Muta. 2). Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and respiratory protection in well-ventilated areas. Avoid skin contact, inhalation, and ingestion completely. Work should be conducted in fume hoods or controlled environments with proper ventilation systems. Regular health monitoring for personnel handling this substance is recommended. Emergency procedures and safety data sheets must be readily available to all workers.

How to store benzene-1,2-diamine;dihydrochloride correctly?

Benzene-1,2-diamine;dihydrochloride must be stored in tightly sealed containers in cool, dry, well-ventilated areas away from heat sources and incompatible materials. Storage areas should be restricted to authorized personnel only, with appropriate warning signs and safety equipment nearby. Keep containers protected from light and moisture to prevent degradation. Ensure proper segregation from oxidizing agents, acids, and other reactive chemicals. Storage facilities must comply with local regulations for carcinogenic substances, including proper containment and emergency response capabilities.

What to do in case of contact with benzene-1,2-diamine;dihydrochloride?

Immediate medical attention is required for any contact with benzene-1,2-diamine;dihydrochloride due to its toxic properties. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15 minutes and seek medical care. If inhaled, move to fresh air and monitor breathing. For ingestion, do not induce vomiting and seek emergency medical treatment immediately. Always consult poison control centers and inform medical personnel about the specific substance involved.

How to dispose of benzene-1,2-diamine;dihydrochloride appropriately?

Benzene-1,2-diamine;dihydrochloride disposal must comply with local and international hazardous waste regulations due to its carcinogenic classification. The substance requires treatment through licensed hazardous waste disposal facilities equipped to handle toxic and potentially carcinogenic materials. Incineration at high temperatures in specialized facilities is typically the preferred disposal method. Small quantities should be collected in appropriate containers and never disposed of through regular waste streams. Documentation and tracking of disposal activities may be required under environmental regulations.

How to transport benzene-1,2-diamine;dihydrochloride?

Benzene-1,2-diamine;dihydrochloride is classified under ADR Class 6.1 (Toxic substances) Packing Group III for transportation purposes. Transport requires appropriate UN-specification packaging with proper labeling including GHS pictograms GHS06, GHS08, and GHS09. Shipping documentation must include safety data sheets and emergency response information. Vehicles must carry appropriate placards and emergency equipment. Transport personnel require hazmat training and certification. Special handling procedures apply during loading, unloading, and transit to prevent exposure and environmental contamination.

Is benzene-1,2-diamine;dihydrochloride subject to specific regulations?

Benzene-1,2-diamine;dihydrochloride is subject to comprehensive chemical safety regulations under REACH and CLP in Europe. Its classification as Carc. 2 and Muta. 2 triggers specific registration, evaluation, and authorization requirements. The substance requires safety data sheets compliant with current regulatory standards and may be subject to workplace exposure limits. Import/export activities must comply with international chemical control conventions. Regular safety assessments and risk management measures are mandatory for industrial users, with potential restrictions on certain applications depending on national implementations.

Where to buy benzene-1,2-diamine;dihydrochloride in Europe?

Benzene-1,2-diamine;dihydrochloride is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substance handling and regulatory compliance. OYSI provides comprehensive documentation including safety data sheets, certificates of analysis, and regulatory support for this controlled substance. As a professional chemical supplier, OYSI ensures proper packaging, labeling, and transportation according to ADR Class 6.1 requirements. Contact OYSI directly for availability, technical specifications, and regulatory guidance for your specific application requirements in the European market.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.