1,2,4-trimethylbenzene

C9H12

CAS95-63-6
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
95-63-6
EC Number
202-436-9
UN Number
3295
Index Number
601-043-00-3
PubChem CID
7247

Physical-chemical properties

Molecular Formula
C9H12
Molar Mass
120.19 g/mol
IUPAC Name
1,2,4-trimethylbenzene

Chemical Identifiers

InChI
InChI=1S/C9H12/c1-7-4-5-8(2)9(3)6-7/h4-6H,1-3H3
InChI Key
GWHJZXXIDMPWGX-UHFFFAOYSA-N

Overview

1,2,4-trimethylbenzene (CAS 95-63-6) is an aromatic hydrocarbon solvent characterized by excellent dissolving properties and moderate volatility. This trimethylbenzene isomer represents one of the most commercially significant aromatic solvents in industrial applications. Also known by its IUPAC designation 1,2,4-trimethylbenzene, this colorless liquid compound features three methyl groups attached to a benzene ring in specific positions, giving it distinctive physical and chemical properties that differentiate it from other isomers like 1,3,5-trimethylbenzene. With a molecular formula of C9H12 and molecular weight of 120.19 g/mol, 1,2,4-trimethylbenzene exhibits typical aromatic solvent characteristics including good thermal stability and selective solvency. The compound is classified as a flammable liquid (Class 3) with moderate acute toxicity potential, requiring appropriate handling precautions. Its hazard profile includes skin and eye irritation properties, along with specific target organ toxicity, making proper safety protocols essential during industrial use. The substance finds extensive application in paint and coating formulations where its solvency power and evaporation rate contribute to optimal film formation. Additionally, it serves as an important intermediate in chemical synthesis processes and as a component in specialty cleaning formulations. Its performance characteristics make it particularly valuable in applications requiring controlled volatility and excellent compatibility with various resins and polymers. Like other aromatic solvents including bromobenzene and chlorobenzene, proper environmental considerations are necessary due to its aquatic toxicity classification. Industrial users benefit from its consistent quality and reliable supply chain availability. OYSI maintains regular stock of high-quality 1,2,4-trimethylbenzene to support European industrial customers' technical solvent requirements.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3295
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping Name1,2,4-Trimethylbenzen
Marine PollutantNo

Frequently Asked Questions

What is 1,2,4-trimethylbenzene?

1,2,4-trimethylbenzene is an aromatic hydrocarbon compound with the molecular formula C9H12 and CAS number 95-63-6. It belongs to the xylene family and consists of a benzene ring substituted with three methyl groups at positions 1, 2, and 4. With a molecular weight of 120.19 g/mol, this colorless liquid is commonly known as pseudocumene and serves as an important industrial solvent and chemical intermediate in various manufacturing processes.

What are the physicochemical properties of 1,2,4-trimethylbenzene?

1,2,4-trimethylbenzene is a colorless liquid at room temperature with a characteristic aromatic odor. It has limited solubility in water due to its hydrophobic nature but is miscible with most organic solvents including alcohols, ethers, and other hydrocarbons. The compound exhibits typical aromatic stability and has a relatively low vapor pressure. Its physical properties make it suitable for use as a solvent in various industrial applications.

What is 1,2,4-trimethylbenzene used for?

1,2,4-trimethylbenzene is primarily used as a solvent in industrial processes, particularly in paint, coating, and adhesive formulations. It serves as a chemical intermediate in the synthesis of other organic compounds and is utilized in the production of specialty chemicals. The compound also finds applications in the manufacturing of polymers, resins, and as a component in fuel additives. Its excellent solvating properties make it valuable in extraction processes and chemical reactions.

How to handle 1,2,4-trimethylbenzene safely?

1,2,4-trimethylbenzene requires careful handling due to its flammable nature and potential health effects. Workers should wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Ensure adequate ventilation to minimize inhalation exposure, as the compound can cause respiratory irritation. Keep away from ignition sources, heat, and sparks. Use non-sparking tools and equipment in areas where the chemical is handled.

How to store 1,2,4-trimethylbenzene correctly?

1,2,4-trimethylbenzene should be stored in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Keep containers tightly closed and in original packaging when not in use. Store in areas with appropriate fire suppression systems and ensure compatibility with storage materials. Avoid storage near oxidizing agents and strong acids. Maintain storage temperatures below 40°C and implement proper inventory rotation to prevent degradation over time.

What to do in case of contact with 1,2,4-trimethylbenzene?

In case of skin contact with 1,2,4-trimethylbenzene, immediately remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush eyes with clean water for 15 minutes while holding eyelids open. If inhaled, move person to fresh air immediately. In case of ingestion, do not induce vomiting and seek medical attention. Contact emergency services if symptoms persist or worsen after initial treatment.

How to dispose of 1,2,4-trimethylbenzene appropriately?

1,2,4-trimethylbenzene must be disposed of according to local, national, and international waste regulations as a hazardous chemical waste. The compound should be collected in appropriate containers and handed over to licensed waste disposal companies for proper treatment. Incineration at authorized facilities with adequate emission controls is typically the preferred disposal method. Empty containers should also be treated as hazardous waste and properly cleaned before disposal or recycling.

How to transport 1,2,4-trimethylbenzene?

1,2,4-trimethylbenzene is classified as ADR Class 3 (flammable liquid), Packing Group III for transportation purposes. It must be transported in UN-approved packaging with proper labeling including flammable liquid hazard labels. Transport vehicles should be equipped with appropriate safety equipment and drivers must hold valid dangerous goods transport certification. Ensure proper documentation accompanies shipments and follow specific routing restrictions for hazardous materials transport.

Is 1,2,4-trimethylbenzene subject to specific regulations?

1,2,4-trimethylbenzene is regulated under European REACH regulation requiring registration for manufacture or import above one tonne per year. It is classified under CLP regulation with harmonized classification including flammable liquid and health hazard categories. The compound is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with occupational exposure limits, safety data sheet requirements, and proper hazard communication in accordance with chemical safety legislation.

Where to buy 1,2,4-trimethylbenzene in Europe?

1,2,4-trimethylbenzene is available through OYSI, a specialized European distributor of technical chemicals serving industrial customers across Europe. OYSI provides high-quality 1,2,4-trimethylbenzene with complete regulatory documentation including safety data sheets and certificates of analysis. As an established chemical distributor, OYSI ensures reliable supply chains and technical support for customers requiring this aromatic solvent for their industrial applications and manufacturing processes.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.