1,2,4-trimethylbenzene

C9H12

CAS95-63-6
GHS02 Gefahrensymbol: Entzündbar – Flamme
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
95-63-6
EC Number
202-436-9
UN Number
3295
Index Number
601-043-00-3
PubChem CID
7247

Physical-chemical properties

Molecular Formula
C9H12
Molar Mass
120.19 g/mol
IUPAC Name
1,2,4-trimethylbenzene

Chemical Identifiers

InChI
InChI=1S/C9H12/c1-7-4-5-8(2)9(3)6-7/h4-6H,1-3H3
InChI Key
GWHJZXXIDMPWGX-UHFFFAOYSA-N

Overview

1,2,4-trimethylbenzene (CAS 95-63-6) is an aromatic hydrocarbon solvent with three methyl substituents on the benzene ring in asymmetric positions. This colorless liquid compound, also known by its systematic IUPAC name 1,2,4-trimethylbenzene, belongs to the family of methylated aromatic hydrocarbons and serves as an important industrial solvent and chemical intermediate. With a molecular formula of C9H12 and molecular weight of 120.19 g/mol, this substance exhibits typical aromatic characteristics while offering unique solvent properties due to its specific substitution pattern on the benzene ring. The compound presents moderate hazard properties, classified as a flammable liquid (Category 3) with potential for acute toxicity, skin and eye irritation, and specific target organ toxicity. Its safety profile requires careful handling with appropriate personal protective equipment and adequate ventilation systems. The substance shows environmental concerns with chronic aquatic toxicity, necessitating proper containment and disposal procedures. In industrial applications, 1,2,4-trimethylbenzene finds primary use as a solvent in paint and coating formulations, where its excellent solvency power and controlled evaporation rate provide optimal performance characteristics. It also serves as a chemical intermediate in the synthesis of various organic compounds and as a component in specialty cleaning formulations. Compared to related compounds like 1,3,5-trimethylbenzene, this isomer offers distinct physical properties that make it particularly suitable for specific solvent applications requiring controlled volatility and compatibility with diverse substrate materials. OYSI maintains reliable supply chains for 1,2,4-trimethylbenzene to support diverse industrial requirements across European markets.

Safety & Classification

Warning
Classification:

Flam. Liq. 3; Acute Tox. 4 *; STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H226

Flammable liquid and vapour.

H332

Harmful if inhaled.

H335

May cause respiratory irritation.

H315

Causes skin irritation.

H319

Causes serious eye irritation.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Irritant

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3295
ADR Class3
Packing GroupIII
Tunnel CodeD/E
Proper Shipping Name1,2,4-Trimethylbenzen
Marine PollutantNo

Frequently Asked Questions

What is 1,2,4-trimethylbenzene?

1,2,4-trimethylbenzene is an aromatic hydrocarbon compound with the molecular formula C9H12 and CAS number 95-63-6. It consists of a benzene ring substituted with three methyl groups at positions 1, 2, and 4. This colorless liquid has a molecular weight of 120.19 g/mol and belongs to the family of trimethylbenzene isomers, also known as pseudocumene.

What are the physicochemical properties of 1,2,4-trimethylbenzene?

1,2,4-trimethylbenzene is a colorless liquid at room temperature with a characteristic aromatic odor. It has low water solubility but is miscible with most organic solvents including alcohols, ethers, and hydrocarbons. The compound is flammable with flash point characteristics that classify it as Flammable Liquid Category 3 under GHS classification.

What is 1,2,4-trimethylbenzene used for?

1,2,4-trimethylbenzene is primarily used as a solvent in industrial applications and as an intermediate in chemical synthesis. It serves as a component in paint thinners, varnishes, and coating formulations. The compound is also utilized in the production of plasticizers, resins, and as a precursor for various aromatic chemicals in pharmaceutical and agrochemical industries.

How to handle 1,2,4-trimethylbenzene safely?

1,2,4-trimethylbenzene requires careful handling due to its flammable nature and potential health effects. Use appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and respiratory protection when necessary. Work in well-ventilated areas away from ignition sources. Avoid skin and eye contact, and prevent inhalation of vapors to minimize acute toxicity and irritation risks.

How to store 1,2,4-trimethylbenzene correctly?

1,2,4-trimethylbenzene should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources, sparks, and open flames. Keep containers in secondary containment to prevent spills. Store away from oxidizing agents and incompatible materials. Ensure storage areas have appropriate fire suppression systems and emergency equipment readily available.

What to do in case of contact with 1,2,4-trimethylbenzene?

1,2,4-trimethylbenzene contact requires immediate action. For skin contact, remove contaminated clothing and wash thoroughly with soap and water. In case of eye contact, rinse immediately with plenty of water for at least 15 minutes. If inhaled, move to fresh air immediately. If swallowed, do not induce vomiting and seek medical attention. Always consult a physician if symptoms persist.

How to dispose of 1,2,4-trimethylbenzene appropriately?

1,2,4-trimethylbenzene disposal must comply with local and national waste regulations as it is classified as hazardous waste. Contact licensed waste disposal contractors for proper treatment and disposal. Never discharge into drains, soil, or water bodies due to its aquatic toxicity classification. Containers should be completely emptied and handled as hazardous waste unless properly cleaned according to regulations.

How to transport 1,2,4-trimethylbenzene?

1,2,4-trimethylbenzene is classified as ADR Class 3 (flammable liquid), Packing Group III for transportation. It requires appropriate packaging, labeling with GHS02, GHS07, and GHS09 pictograms, and proper shipping documentation. Transport vehicles must comply with ADR regulations for flammable liquids, including appropriate fire extinguishing equipment and driver training requirements.

Is 1,2,4-trimethylbenzene subject to particular regulations?

1,2,4-trimethylbenzene is regulated under various European legislations including REACH and CLP regulations. It is not currently listed as a Substance of Very High Concern (SVHC). Users must comply with classification and labeling requirements showing Warning signal word and appropriate hazard pictograms. Industrial users should check for any sector-specific restrictions or authorization requirements.

Where to buy 1,2,4-trimethylbenzene in Europe?

1,2,4-trimethylbenzene is available through OYSI, a European distributor of chemical products specializing in industrial chemicals. OYSI provides reliable supply chains across Europe with proper documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for availability, specifications, packaging options, and delivery arrangements to meet your specific industrial requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.