Naphthalen-1-amine

C10H9N

naphthalen-1-amine

CAS134-32-7
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
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Identification

CAS Number
134-32-7
EC Number
205-138-7
UN Number
2077
Index Number
612-020-00-2
PubChem CID
8640

Physical-chemical properties

Molecular Formula
C10H9N
Molar Mass
143.18 g/mol
IUPAC Name
naphthalen-1-amine

Chemical Identifiers

InChI
InChI=1S/C10H9N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,11H2
InChI Key
RUFPHBVGCFYCNW-UHFFFAOYSA-N

Overview

Naphthalen-1-amine (CAS 134-32-7) is an aromatic amine compound derived from naphthalene with primary amine functionality at the 1-position. This organic chemical intermediate, also known as 1-naphthylamine, represents a fundamental building block in synthetic organic chemistry. With its molecular formula C10H9N and molecular weight of 143.18 g/mol, naphthalen-1-amine features a bicyclic aromatic naphthalene ring system substituted with an amino group. The compound exhibits characteristic properties of aromatic amines, including moderate basicity and nucleophilic reactivity at the nitrogen center. From a safety perspective, naphthalen-1-amine is classified under GHS with pictograms GHS07 and GHS09, indicating acute toxicity (Category 4) and environmental hazards (Aquatic Chronic 2). The warning signal word reflects its moderate hazard profile, requiring appropriate handling precautions including personal protective equipment and controlled storage conditions. Transportation falls under ADR Class 6.1, designating it as a toxic substance requiring specialized shipping protocols. Industrial applications of naphthalen-1-amine primarily center on its role as a chemical intermediate in dye manufacturing, particularly for the production of azo dyes and other colorants. The compound also serves as a precursor in pharmaceutical synthesis and rubber antioxidant production. While structurally different from compounds like 2-cyclohexylidene-2-phenylacetonitrile, both serve important roles as specialized chemical intermediates in industrial synthesis pathways. OYSI provides naphthalen-1-amine to European industrial customers requiring high-quality aromatic amine intermediates for specialized chemical manufacturing applications, supported by comprehensive technical documentation and regulatory compliance assistance.

Safety & Classification

Warning
Classification:

Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number2077
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Namealpha-Naphthylamin, fest
Marine PollutantNo

Frequently Asked Questions

What is naphthalen-1-amine?

Naphthalen-1-amine is an aromatic amine compound with the molecular formula C10H9N and CAS number 134-32-7. This organic chemical consists of a naphthalene ring system with an amino group (-NH2) attached at position 1. With a molecular weight of 143.18 g/mol, it belongs to the class of primary aromatic amines and exhibits moderate toxicity requiring careful handling and safety precautions.

What are the physicochemical properties of naphthalen-1-amine?

Naphthalen-1-amine appears as white to reddish crystalline solid at room temperature, though it may darken upon exposure to light and air. The compound has a characteristic amine odor and exhibits limited water solubility but dissolves readily in organic solvents such as ethanol, ether, and benzene. Its aromatic structure provides stability while the amino group contributes to its chemical reactivity and hydrogen bonding capabilities.

What is naphthalen-1-amine used for?

Naphthalen-1-amine serves primarily as an intermediate in the synthesis of dyes, particularly azo dyes and other colored compounds used in textile and printing industries. It is also utilized in the production of antioxidants, rubber chemicals, and pharmaceutical intermediates. The compound finds application in analytical chemistry as a reagent and in the manufacture of specialty chemicals requiring aromatic amine functionality.

How to handle naphthalen-1-amine safely?

Naphthalen-1-amine requires careful handling due to its Acute Tox. 4 classification and Warning signal word. Essential personal protective equipment includes nitrile gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation. Avoid eating, drinking, or smoking when handling this material, and wash hands thoroughly after use.

How to store naphthalen-1-amine correctly?

Naphthalen-1-amine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from direct sunlight to prevent discoloration and degradation. Keep away from oxidizing agents, acids, and incompatible materials. Storage areas should be equipped with appropriate spill containment measures and maintained at stable temperatures. Ensure containers are properly labeled and stored according to local chemical storage regulations.

What to do in case of contact with naphthalen-1-amine?

Immediate action is required upon contact with naphthalen-1-amine. For skin contact, remove contaminated clothing and wash affected area thoroughly with soap and water for at least 15 minutes. In case of eye contact, rinse immediately with plenty of clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek medical attention if symptoms develop or persist after exposure.

How to dispose of naphthalen-1-amine properly?

Naphthalen-1-amine waste must be disposed of through licensed hazardous waste disposal facilities in accordance with local, national, and EU waste regulations. The material cannot be disposed of in regular waste streams due to its toxicity and environmental impact classification (Aquatic Chronic 2). Small quantities should be collected in appropriate containers and arranged for professional disposal through certified waste management companies specializing in chemical waste.

How to transport naphthalen-1-amine?

Naphthalen-1-amine is classified under ADR Class 6.1 (Toxic substances), Packing Group III for transportation purposes. This classification requires specific packaging, marking, and documentation according to dangerous goods regulations. Transport must comply with ADR requirements including proper packaging specifications, hazard labels (GHS07, GHS09), and shipping papers. Only trained personnel should handle transportation of this regulated chemical substance.

Is naphthalen-1-amine subject to specific regulations?

Naphthalen-1-amine is subject to REACH regulation requiring registration for manufacture or import above one tonne per year in the EU. The substance must comply with CLP regulation for classification, labeling, and packaging as indicated by its GHS pictograms (GHS07, GHS09) and Warning signal word. While not currently listed as SVHC, users must follow standard chemical safety protocols and maintain safety data sheets for workplace compliance.

Where to buy naphthalen-1-amine in Europe?

Naphthalen-1-amine is available through OYSI, a leading European distributor of specialty chemicals serving industrial and research customers across the continent. OYSI provides quality chemical products with proper documentation, safety data sheets, and regulatory compliance support. As an established supplier, OYSI ensures reliable availability and professional service for customers requiring this aromatic amine compound for their applications.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.