2-chloro-4-nitroaniline

2-chloro-4-nitroaniline is an aromatic amine compound with the molecular formula C6H5ClN2O2 and CAS number 121-87-9. This chemical features both chlorine and nitro functional groups attached to an aniline ring, giving it a molecular weight of 172.57 g/mol. It belongs to the class of substituted anilines and is classified as a moderately toxic substance with chronic aquatic toxicity properties under GHS classification.

2-chloro-4-nitroaniline is typically a crystalline solid at room temperature with a yellowish to orange color. As an aromatic amine with electron-withdrawing groups (chlorine and nitro), it exhibits moderate polarity and limited water solubility. The compound has a distinctive chemical odor typical of substituted anilines. Its melting and boiling points are elevated due to intermolecular hydrogen bonding from the amino group.

2-chloro-4-nitroaniline is primarily used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It serves as a building block in the production of azo dyes and various organic compounds in the chemical industry. The compound is also utilized in research and development applications for the synthesis of specialized chemicals and materials. Its dual functional groups make it valuable for creating complex molecular structures.

2-chloro-4-nitroaniline requires careful handling with appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation exposure. Given its Acute Tox. 4 classification, avoid skin contact and ingestion. Use non-sparking tools and ensure proper grounding when handling to prevent static electricity buildup.

2-chloro-4-nitroaniline should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and direct sunlight. Keep away from incompatible materials such as strong oxidizers, acids, and bases. Storage areas should be equipped with appropriate spill containment measures. Ensure containers are properly labeled and stored according to local regulations for toxic substances.

In case of skin contact with 2-chloro-4-nitroaniline, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move the person to fresh air immediately. For eye contact, flush with clean water for at least 15 minutes. Seek medical attention if symptoms persist or if significant exposure has occurred. Do not induce vomiting if ingested.

2-chloro-4-nitroaniline must be disposed of as hazardous waste according to local and national regulations. The substance cannot be disposed of in regular waste streams due to its toxicity and environmental impact classification (Aquatic Chronic 2). Contact licensed hazardous waste disposal companies for proper treatment and disposal. Small laboratory quantities may require incineration at high temperatures in specialized facilities equipped with emission controls.

2-chloro-4-nitroaniline is classified under ADR Class 6.1 (Toxic substances) Packing Group III, requiring specific transport regulations. Packages must be properly labeled with appropriate hazard markings and UN identification numbers. Transport vehicles should carry emergency response information and appropriate spill cleanup materials. Drivers must hold valid ADR certification for transporting toxic substances, and shipments must comply with routing and documentation requirements.

2-chloro-4-nitroaniline is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification obligations. The substance must be handled according to occupational safety standards and environmental protection laws. While not currently listed as a Substance of Very High Concern (SVHC), it requires proper risk assessment and safety data sheet provision. Import/export may require specific permits depending on jurisdiction.

2-chloro-4-nitroaniline is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides reliable supply chains for industrial and research applications across Europe, ensuring proper handling, documentation, and regulatory compliance. As a professional chemical supplier, OYSI maintains appropriate certifications and provides comprehensive safety data sheets and technical support for customers requiring this specialized aromatic amine compound.