5-tert-butyl-2-methylbenzenethiol

5-tert-butyl-2-methylbenzenethiol is an organosulfur compound with the molecular formula C11H16S and CAS number 7340-90-1. This aromatic thiol features a benzene ring substituted with a tert-butyl group, a methyl group, and a thiol (-SH) functional group. With a molecular weight of 180.31 g/mol, it belongs to the class of substituted benzenethiols and exhibits characteristic sulfur-containing compound properties including a distinctive odor.

5-tert-butyl-2-methylbenzenethiol is typically a liquid at room temperature with characteristic thiol properties. As an aromatic thiol compound, it exhibits a strong, distinctive sulfur-like odor typical of mercaptan compounds. The substance is classified as a flammable liquid (Flam. Liq. 3) and has limited water solubility due to its hydrophobic aromatic structure with bulky alkyl substituents, making it more soluble in organic solvents.

5-tert-butyl-2-methylbenzenethiol is primarily used as a chemical intermediate in organic synthesis and pharmaceutical manufacturing. Its thiol functional group makes it valuable for various chemical reactions including thiol-ene coupling, metal coordination chemistry, and as a building block for more complex molecules. It may also find applications in materials science, polymer chemistry, and as a specialty reagent in research and development applications within the chemical industry.

5-tert-butyl-2-methylbenzenethiol requires careful handling due to its multiple hazard classifications including skin and eye irritation, skin sensitization, and reproductive toxicity. Always wear appropriate personal protective equipment including chemical-resistant gloves, safety goggles, and protective clothing. Work in well-ventilated areas or under fume hoods to avoid inhalation. Prevent skin and eye contact, avoid ignition sources due to its flammable nature, and ensure proper grounding when transferring the substance.

5-tert-butyl-2-methylbenzenethiol should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat, sparks, and ignition sources due to its flammable properties. Keep containers upright and protected from physical damage. Store separately from oxidizing agents, strong acids, and incompatible materials. Maintain storage temperatures according to supplier specifications and ensure proper labeling with hazard information. Regular inspection of containers for leaks or deterioration is recommended.

In case of skin contact with 5-tert-butyl-2-methylbenzenethiol, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15-20 minutes and remove contact lenses if present. If inhaled, move to fresh air immediately. Seek medical attention if irritation persists or if large amounts were involved. Never induce vomiting if ingested due to aspiration toxicity risks.

5-tert-butyl-2-methylbenzenethiol must be disposed of according to local, national, and European waste regulations as hazardous chemical waste. Do not pour down drains or dispose of in regular trash due to its hazardous properties and environmental concerns. Contact licensed hazardous waste disposal companies for proper collection and treatment. Small quantities should be collected in appropriate containers and labeled clearly. Always consult safety data sheets and local environmental authorities for specific disposal requirements.

5-tert-butyl-2-methylbenzenethiol is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. It must be packaged in UN-approved containers with proper labeling and documentation including transport documents and emergency response information. Vehicles must comply with ADR requirements for Class 9 substances. Drivers need appropriate training and certification. Ensure proper segregation from incompatible materials during transport and follow emergency response procedures if incidents occur.

5-tert-butyl-2-methylbenzenethiol is subject to European REACH regulation requiring registration for manufacture or import above certain tonnages. It must be classified and labeled according to CLP regulation with appropriate hazard pictogrammes (GHS02, GHS07, GHS08, GHS09) and danger signal word. While not currently listed as SVHC, its reproductive toxicity classification may trigger additional regulatory scrutiny. Companies must maintain safety data sheets and ensure downstream user communication of hazard information.

5-tert-butyl-2-methylbenzenethiol is available through OYSI, a specialized European distributor of technical chemicals serving various industries across Europe. OYSI provides reliable supply chains for specialty chemicals with proper documentation, safety data sheets, and regulatory compliance support. As a professional chemical distributor, OYSI ensures product quality, appropriate packaging, and technical support for industrial customers requiring this specialized aromatic thiol compound for their applications.