2-phenylphenol

C12H10O

CAS90-43-7
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
90-43-7
EC Number
201-993-5
UN Number
3077
Index Number
604-020-00-6
PubChem CID
7017

Physical-chemical properties

Molecular Formula
C12H10O
Molar Mass
170.21 g/mol
IUPAC Name
2-phenylphenol

Chemical Identifiers

InChI
InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H
InChI Key
LLEMOWNGBBNAJR-UHFFFAOYSA-N

Overview

2-phenylphenol (CAS 90-43-7) is an aromatic phenolic compound with antimicrobial properties and industrial preservative applications. This biphenyl derivative, also known by its IUPAC name 2-phenylphenol, represents a significant chemical intermediate in various industrial processes. With its molecular formula C12H10O and molecular weight of 170.21 g/mol, this white crystalline solid exhibits distinctive phenolic characteristics that make it valuable across multiple sectors. The compound's structure consists of two benzene rings connected directly, with a hydroxyl group positioned ortho to the phenyl substituent, contributing to its unique chemical reactivity and biological activity. From a safety perspective, 2-phenylphenol requires careful handling due to its classification as a Category 2 carcinogen and skin corrosive substance. The compound carries the danger signal word and multiple GHS pictograms (GHS08, GHS05, GHS07, GHS09), reflecting its potential health hazards including skin sensitization, eye damage, and aquatic toxicity. Its ADR Class 9 classification indicates it falls under miscellaneous dangerous goods for transportation purposes. Industrial applications of 2-phenylphenol primarily center around its antimicrobial properties, making it valuable in disinfectant formulations and preservation systems. The compound serves as an effective fungicide and bactericide in agricultural applications, while also functioning as an intermediate in pharmaceutical synthesis. Its structural similarity to compounds like benzene-1,4-diol demonstrates its place within the broader phenolic compound family, though its biphenyl structure provides enhanced stability and specific biological activity profiles. OYSI maintains reliable supply chains for 2-phenylphenol to support diverse European industrial requirements, ensuring consistent quality and regulatory compliance for technical applications.

Safety & Classification

Danger
Classification:

Carc. 2; Skin Corr. 1; Eye Dam. 1; Skin Sens. 1B; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H351

Suspected of causing cancer.

H314

Causes severe skin burns and eye damage.

H318

Causes serious eye damage.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2-Phenylphenol (ISO)
Marine PollutantNo

Frequently Asked Questions

What is 2-phenylphenol?

2-phenylphenol is an organic aromatic compound with the molecular formula C12H10O and a molar mass of 170.21 g/mol. It belongs to the phenol family and is characterized by two benzene rings connected through a phenolic hydroxyl group. This compound is widely recognized for its antimicrobial and preservative properties, making it valuable in various industrial applications where microbial control is essential.

What are the physicochemical properties of 2-phenylphenol?

2-phenylphenol appears as white to light yellow crystalline flakes or powder at room temperature. It has a characteristic phenolic odor and exhibits limited solubility in water but dissolves well in organic solvents such as alcohols and acetone. The compound has a melting point around 56-58°C and demonstrates good thermal stability under normal storage conditions, making it suitable for various industrial formulations.

What is 2-phenylphenol used for?

2-phenylphenol is primarily used as an antimicrobial agent and preservative in industrial applications. It serves as a disinfectant in cleaning products, acts as a fungicide in agricultural formulations, and functions as a preservative in cosmetic and personal care products. Additionally, it is utilized in the production of resins, as an intermediate in chemical synthesis, and in certain specialty applications requiring antimicrobial properties.

How to handle 2-phenylphenol safely?

2-phenylphenol requires careful handling due to its corrosive and sensitizing properties. Essential protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or use local exhaust ventilation to minimize inhalation exposure. Avoid generating dust and ensure proper training on emergency procedures. Never eat, drink, or smoke while handling this substance.

How to store 2-phenylphenol correctly?

2-phenylphenol should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials such as strong oxidizing agents and bases. Maintain storage temperatures below 25°C when possible and ensure proper labeling according to GHS requirements. Implement appropriate spill containment measures in storage areas.

What to do in case of contact with 2-phenylphenol?

Immediate action is required for any contact with 2-phenylphenol due to its corrosive nature. For skin contact, immediately remove contaminated clothing and flush affected areas with plenty of water for at least 15 minutes. For eye contact, rinse continuously with water and seek immediate medical attention. If inhaled, move to fresh air immediately. In all cases of exposure, seek professional medical advice and provide the safety data sheet to healthcare providers.

How to dispose of 2-phenylphenol appropriately?

2-phenylphenol must be disposed of as hazardous waste in accordance with local and national environmental regulations. Contact licensed waste disposal companies specializing in hazardous chemical waste. Never dispose of this substance through regular waste streams or pour down drains due to its aquatic toxicity. Ensure proper documentation of waste disposal and consider waste minimization strategies such as recycling or recovery where technically feasible and economically viable.

How to transport 2-phenylphenol?

2-phenylphenol is classified as ADR Class 9 (miscellaneous dangerous goods), Packing Group III for transport purposes. Use approved packaging that meets UN specification requirements and ensure proper hazard labeling on packages. Transport documentation must include the correct shipping name and UN identification number. Vehicles must carry appropriate emergency equipment and drivers should be trained in hazardous materials handling procedures according to ADR regulations.

Is 2-phenylphenol subject to specific regulations?

2-phenylphenol is subject to comprehensive chemical safety regulations including REACH registration requirements in the European Union and CLP classification as a Category 2 carcinogen. It requires safety data sheets, proper labeling with GHS pictograms (GHS05, GHS07, GHS08, GHS09), and the danger signal word. Users must implement appropriate risk management measures and comply with occupational exposure limits where established by national authorities.

Where to buy 2-phenylphenol in Europe?

2-phenylphenol is available through OYSI, a trusted European distributor of technical chemicals. OYSI provides this substance with complete regulatory documentation including safety data sheets and certificates of analysis. As a specialized chemical distributor, OYSI ensures compliance with European regulations and offers technical support for proper handling and application guidance. Contact OYSI directly for availability, specifications, and delivery options across European markets.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.