2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride is an organic chemical compound with the molecular formula C8H11Cl2NO2 and CAS number 72830-09-2. This pyridine derivative features a chloromethyl group and two methoxy substituents on the pyridine ring, supplied as a hydrochloride salt. With a molecular weight of 224.08 g/mol, it is classified as a hazardous substance requiring careful handling due to its toxicity and irritant properties.

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride is a solid compound at room temperature, typically appearing as a crystalline powder. As a hydrochloride salt, it exhibits good water solubility, which is characteristic of organic hydrochloride compounds. The presence of methoxy groups and the chloromethyl substituent influences its polarity and solubility profile. The compound's exact melting point, boiling point, and detailed solubility data should be confirmed through technical documentation.

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride is primarily used as an intermediate in pharmaceutical and fine chemical synthesis. The chloromethyl group serves as a reactive handle for further chemical transformations, while the methoxy-substituted pyridine core provides a valuable building block for drug development. It is commonly employed in research and development applications, particularly in medicinal chemistry for the synthesis of bioactive compounds and pharmaceutical intermediates.

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride requires careful handling due to its classification as Acute Tox. 4, Skin Irrit. 2, Eye Dam. 1, and Skin Sens. 1. Essential PPE includes chemical-resistant gloves, safety goggles, and lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. Prevent skin and eye contact, and avoid generating dust. Use appropriate handling tools and ensure proper training before use. Emergency eyewash and shower facilities should be readily accessible.

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride should be stored in a cool, dry, well-ventilated area away from incompatible materials. Keep containers tightly closed and protected from moisture and heat sources. Store in original labeled containers in a designated chemical storage area with appropriate safety measures. Due to its hazardous classification, ensure storage complies with local regulations and is separated from food, feed, and living areas. Regular inventory and condition checks are recommended.

Immediate action is required due to the compound's eye damage and skin irritation potential. For eye contact, rinse immediately with plenty of water for at least 15 minutes and seek medical attention. For skin contact, wash thoroughly with soap and water, remove contaminated clothing. If inhaled, move to fresh air immediately. In case of ingestion, do not induce vomiting and seek medical attention. Always consult the safety data sheet for complete first aid procedures.

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride disposal must comply with local, national, and EU waste regulations due to its hazardous classification. The compound should be treated as hazardous waste and disposed of through licensed waste management companies. Never discharge into drains, waterways, or soil due to its aquatic toxicity classification. Contaminated packaging should also be treated as hazardous waste. Contact local authorities or waste management specialists for specific disposal requirements in your region.

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride is classified under ADR Class 9 (Miscellaneous dangerous substances), Packing Group III. This classification requires appropriate packaging, labeling, and documentation for transport. Use UN-approved packaging and ensure proper hazard labels are affixed. Transport documents must include the correct shipping name, UN number, and hazard class. Only use qualified carriers experienced in handling Class 9 dangerous goods and ensure compliance with ADR regulations.

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride is subject to EU CLP regulation due to its hazardous classification requiring GHS pictograms (GHS05, GHS07, GHS08, GHS09) and 'Danger' signal word. It falls under REACH regulation requiring registration for manufacture or import above one tonne annually. The compound is not currently listed as an SVHC (Substance of Very High Concern). Users must comply with occupational safety regulations and may need to conduct chemical safety assessments depending on use quantities.

2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride is available through OYSI, a European chemical distributor specializing in fine chemicals and pharmaceutical intermediates. As a professional supplier, OYSI ensures proper handling, packaging, and regulatory compliance for hazardous substances. Contact OYSI directly for availability, specifications, and technical support. Due to the compound's hazardous nature, purchases typically require appropriate business credentials and compliance with relevant regulations for professional use only.