2-(chloromethyl)-3,4-dimethoxypyridine;hydrochloride

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride is an organic chemical compound with the molecular formula C8H11Cl2NO2 and CAS number 72830-09-2. This pyridine derivative features a chloromethyl group and two methoxy substituents, existing as a hydrochloride salt with a molecular weight of 224.08 g/mol. It is classified as a hazardous substance requiring careful handling due to its toxicological properties.

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride is a solid crystalline compound at room temperature, typical of hydrochloride salts. As a pyridine derivative with methoxy groups, it likely exhibits moderate polarity and water solubility due to the hydrochloride form. The presence of chlorine and nitrogen atoms contributes to its chemical reactivity, while the methoxy groups influence its solubility characteristics in organic solvents.

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride serves as an important intermediate in pharmaceutical and fine chemical synthesis. The chloromethyl group acts as a reactive site for nucleophilic substitution reactions, while the methoxy-substituted pyridine core provides a valuable building block for drug development and specialty chemical manufacturing. It is primarily used in research and development applications within the pharmaceutical industry.

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride requires careful handling due to its classification as Acute Tox. 4, Skin Irrit. 2, Eye Dam. 1, and Skin Sens. 1. Essential PPE includes chemical-resistant gloves, safety goggles, and lab coats. Work in well-ventilated areas or under fume hoods to prevent inhalation exposure. Avoid skin and eye contact, and ensure proper hygiene practices including thorough handwashing after handling.

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from incompatible materials. Keep containers protected from moisture and light to prevent degradation. Store separately from strong bases, oxidizing agents, and reducing agents. Maintain storage temperatures below 25°C and ensure proper labeling with hazard information. Regular inventory checks should be performed to monitor container integrity.

Immediate action is required upon contact with 2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with water for 15-20 minutes and seek medical attention due to potential eye damage. If inhaled, move to fresh air immediately. Seek medical advice if symptoms persist or worsen.

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride must be disposed of as hazardous chemical waste in accordance with local and national regulations. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Never dispose of this substance down drains, in regular trash, or by burning. Maintain detailed waste disposal records and follow your organization's chemical waste management protocols to ensure regulatory compliance.

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride is classified as ADR Class 9 (Miscellaneous Dangerous Substances), Packing Group III for transportation. This classification requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Transport vehicles must display proper placards, and drivers need hazmat certification. Shipping documents must include proper shipping names, UN numbers, and emergency contact information to ensure safe transport compliance.

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride is subject to REACH regulation in Europe, requiring registration for commercial use above threshold quantities. It falls under CLP regulation with mandatory hazard classification and labeling requirements. While not currently listed as SVHC, its hazardous properties require compliance with occupational health and safety regulations, environmental protection laws, and proper chemical inventory reporting in most jurisdictions.

2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride is available through OYSI, a specialized European distributor of chemical products. As a professional chemical supplier, OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support. Contact OYSI directly for availability, specifications, and pricing information. Their expertise ensures you receive quality products meeting European regulatory standards for research and industrial applications.