Nickel(2+) diacetate

C4H6NiO4

nickel(2+) diacetate

CAS373-02-4
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
373-02-4
EC Number
206-761-7
UN Number
3077
Index Number
028-022-00-6
PubChem CID
9756

Physical-chemical properties

Molecular Formula
C4H6NiO4
Molar Mass
176.78 g/mol
IUPAC Name
nickel(2+) diacetate

Chemical Identifiers

InChI
InChI=1S/2C2H4O2.Ni/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
InChI Key
AIYYMMQIMJOTBM-UHFFFAOYSA-L

Overview

Nickel(2+) diacetate (CAS 373-02-4) is an inorganic nickel salt with notable catalytic properties and significant health hazards requiring careful handling protocols. Nickel(2+) diacetate, also known as nickel acetate, represents a critical chemical compound in various industrial applications where nickel's catalytic and electrochemical properties are essential. This crystalline salt, with the molecular formula C4H6NiO4 and a molecular weight of 176.78 g/mol, serves as an important source of nickel ions in controlled chemical processes. The compound's EC number 206-761-7 identifies it within European chemical regulations, where it is classified under multiple serious hazard categories. The substance presents significant safety considerations, classified as a Category 1A carcinogen, Category 2 mutagen, and Category 1B reproductive toxicant. Additional hazards include acute toxicity, specific target organ toxicity following repeated exposure, and both respiratory and skin sensitization potential. These properties necessitate stringent handling protocols and appropriate personal protective equipment. The compound falls under ADR Class 9 for transportation, indicating miscellaneous dangerous goods requiring special shipping considerations. Industrial applications of nickel(2+) diacetate primarily include electroplating operations, where it provides uniform nickel deposition, and as a catalyst precursor in organic synthesis reactions. The compound also finds use in the production of specialized nickel-based materials and in certain battery manufacturing processes. While sharing some applications with related compounds like cobalt(2+) sulfate in electrochemical applications, nickel(2+) diacetate offers distinct advantages in specific catalytic processes. OYSI maintains reliable supplies of nickel(2+) diacetate to support European industrial operations requiring this specialized chemical compound.

Safety & Classification

Danger
Classification:

Carc. 1A; Muta. 2; Repr. 1B; Acute Tox. 4 *; Acute Tox. 4 *; STOT RE 1; Resp. Sens. 1; Skin Sens....

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H341

Suspected of causing genetic defects.

H332

Harmful if inhaled.

H302

Harmful if swallowed.

H372

Causes damage to organs through prolonged or repeated exposure.

H334

May cause allergy or asthma symptoms or breathing difficulties if inhaled.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Inhalation

Harmful

Measures if vapours or dust are inhaled

First Aid Actions

  • +P304IF INHALED:
  • +P340Remove person to fresh air and keep comfortable for breathing.
  • +P311Call a POISON CENTER/doctor.

Related hazard statements:

Skin Contact

Irritant

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping NameNickel(II)-acetat
Marine PollutantNo

Frequently Asked Questions

What is nickel(2+) diacetate?

Nickel(2+) diacetate is an inorganic chemical compound with the molecular formula C4H6NiO4 and CAS number 373-02-4. This nickel salt has a molecular weight of 176.78 g/mol and appears typically as green crystalline solid. It is classified as a highly hazardous substance with carcinogenic, mutagenic, and reproductive toxicity properties. The compound is widely used in industrial applications but requires strict safety measures due to its severe health hazards including respiratory and skin sensitization potential.

What are the physicochemical properties of nickel(2+) diacetate?

Nickel(2+) diacetate is a green crystalline solid at room temperature with good water solubility. The compound has a molecular weight of 176.78 g/mol and contains two acetate groups bound to a nickel(II) ion. It is hygroscopic and can form hydrated forms under ambient conditions. The substance is stable under normal conditions but may decompose upon heating, releasing toxic fumes. Its solubility in water makes it readily bioavailable, contributing to its toxicological concerns.

What is nickel(2+) diacetate used for?

Nickel(2+) diacetate is primarily used as a catalyst in various chemical synthesis processes and as a precursor for preparing other nickel compounds. It serves in electroplating applications, textile dyeing, and as a mordant in the printing industry. The compound is also utilized in the production of specialized ceramics and as a component in certain analytical reagents. Due to its hazardous properties, its use is increasingly restricted and requires specialized handling procedures in industrial settings.

How to handle nickel(2+) diacetate safely?

Nickel(2+) diacetate requires strict safety protocols due to its carcinogenic and sensitizing properties. Personnel must wear appropriate respiratory protection, chemical-resistant gloves, and protective clothing to prevent skin and inhalation exposure. Work should be conducted in well-ventilated areas or under fume hoods. Avoid generating dust and ensure proper containment during handling. Regular health monitoring is recommended for workers exposed to this substance. Emergency shower and eyewash facilities must be readily accessible in work areas.

How to store nickel(2+) diacetate correctly?

Nickel(2+) diacetate must be stored in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and reducing agents. The substance should be kept in tightly sealed containers to prevent moisture absorption and contamination. Storage areas must be restricted to authorized personnel only, with appropriate warning signs and emergency procedures posted. Keep away from heat sources and ensure proper segregation from food, feed, and other consumer products. Regular container inspection is essential.

What to do in case of contact with nickel(2+) diacetate?

Immediate action is required upon contact with nickel(2+) diacetate due to its toxic and sensitizing properties. For skin contact, immediately remove contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes. If inhaled, move the person to fresh air immediately and seek medical attention. For eye contact, flush with clean water for at least 15 minutes. In all cases of exposure, seek immediate medical attention and provide the safety data sheet to medical personnel.

How to dispose of nickel(2+) diacetate appropriately?

Nickel(2+) diacetate must be disposed of as hazardous waste through licensed waste management facilities in accordance with local and European regulations. The substance cannot be discharged to sewers, water bodies, or regular waste streams due to its environmental toxicity and heavy metal content. Container residues require the same disposal considerations as the pure substance. Waste generators must maintain proper documentation and follow chain-of-custody procedures. Consult local environmental authorities for specific disposal requirements in your region.

How to transport nickel(2+) diacetate?

Nickel(2+) diacetate is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. The substance must be packaged in UN-approved containers with proper labeling including GHS pictograms GHS07, GHS08, and GHS09. Transport documents must include the correct shipping name and hazard information. Drivers must carry appropriate emergency response information and personal protective equipment. Special handling procedures apply during loading, transport, and unloading to prevent environmental release and personnel exposure.

Is nickel(2+) diacetate subject to specific regulations?

Nickel(2+) diacetate is subject to extensive European regulations including REACH registration requirements and CLP classification as Carcinogenic 1A, Mutagenic 2, and Reproductive toxicant 1B. The substance falls under various national occupational exposure limits and may be subject to authorization procedures under REACH. Manufacturing and use restrictions apply in many applications, particularly consumer products. Companies handling this substance must comply with worker protection regulations, environmental permits, and reporting requirements. Regular regulatory updates should be monitored as restrictions continue to evolve.

Where to buy nickel(2+) diacetate in Europe?

Nickel(2+) diacetate is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous materials handling. As a professional chemical supplier, OYSI ensures proper regulatory compliance, documentation, and safe delivery throughout Europe. The company provides technical support, safety data sheets, and regulatory guidance for industrial customers. Due to the substance's hazardous nature, purchases are typically restricted to qualified industrial users with appropriate handling capabilities and regulatory permits. Contact OYSI directly for availability and specific requirements.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.