5-ethyl-2-methylpyridine

C8H11N

CAS104-90-5

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Identification

CAS Number
104-90-5
EC Number
203-250-0
UN Number
2300
PubChem CID
7728

Physical-chemical properties

Molecular Formula
C8H11N
Molar Mass
121.18 g/mol
IUPAC Name
5-ethyl-2-methylpyridine

Chemical Identifiers

InChI
InChI=1S/C8H11N/c1-3-8-5-4-7(2)9-6-8/h4-6H,3H2,1-2H3
InChI Key
NTSLROIKFLNUIJ-UHFFFAOYSA-N

Overview

5-ethyl-2-methylpyridine (CAS 104-90-5) is a substituted pyridine derivative with ethyl and methyl substituents that exhibits characteristic heterocyclic nitrogen compound properties. This organic compound belongs to the alkylpyridine family, featuring a six-membered aromatic ring containing one nitrogen atom with both ethyl and methyl substituents at the 5 and 2 positions respectively. With a molecular formula of C8H11N and molecular weight of 121.18 g/mol, 5-ethyl-2-methylpyridine represents an important intermediate in organic synthesis and pharmaceutical chemistry. The compound's structure combines the basic properties of pyridine with the modified reactivity patterns introduced by the alkyl substituents, which influence both its chemical behavior and physical properties. The substitution pattern of 5-ethyl-2-methylpyridine affects its basicity compared to unsubstituted pyridine, with the electron-donating methyl and ethyl groups generally increasing the compound's nucleophilicity. This makes it particularly valuable as a building block in the synthesis of more complex heterocyclic compounds. While classified under ADR Class 6.1, indicating potential toxicity concerns, the compound requires appropriate handling protocols and safety measures during storage and processing. Industrial applications of 5-ethyl-2-methylpyridine primarily focus on pharmaceutical intermediate synthesis, agrochemical production, and specialty chemical manufacturing. The compound serves as a precursor in the development of various therapeutic agents and crop protection chemicals. Unlike simpler aromatic compounds such as 4-nitroaniline, the alkylated pyridine structure offers unique reactivity profiles that enable specific synthetic transformations in medicinal chemistry applications. OYSI provides 5-ethyl-2-methylpyridine to support diverse industrial synthesis requirements across European markets, ensuring reliable supply for pharmaceutical and specialty chemical manufacturers.

Safety & Classification

No Hazard Classification

This substance is not classified as hazardous according to CLP Regulation (EC) No 1272/2008.

Transport (ADR)

UN Number2300
ADR Class6.1
Packing GroupIII
Tunnel CodeE
Proper Shipping Name2-Methyl-5-ethylpyridin
Marine PollutantNo

Frequently Asked Questions

What is 5-ethyl-2-methylpyridine?

5-ethyl-2-methylpyridine is an organic chemical compound belonging to the pyridine family with the molecular formula C8H11N and CAS number 104-90-5. This substituted pyridine derivative features an ethyl group at position 5 and a methyl group at position 2 of the pyridine ring. With a molecular weight of 121.18 g/mol, it serves as an important intermediate in organic synthesis and pharmaceutical applications.

What are the physicochemical properties of 5-ethyl-2-methylpyridine?

5-ethyl-2-methylpyridine is a liquid organic compound at room temperature with characteristic pyridine-like odor. As a nitrogen-containing heterocyclic compound, it exhibits basic properties typical of substituted pyridines. The compound is generally soluble in organic solvents and shows limited water solubility. Its boiling point and other physical properties are influenced by the ethyl and methyl substituents on the pyridine ring structure.

What is 5-ethyl-2-methylpyridine used for?

5-ethyl-2-methylpyridine is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a building block for the production of various pharmaceutical compounds, agrochemicals, and fine chemicals. The compound is valuable in medicinal chemistry for developing drug molecules and in the synthesis of complex organic compounds where substituted pyridine structures are required as key components.

How to handle 5-ethyl-2-methylpyridine safely?

5-ethyl-2-methylpyridine should be handled with standard laboratory safety precautions including wearing appropriate personal protective equipment such as safety glasses, gloves, and lab coats. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation exposure. Despite having no specific GHS classification, treat as potentially hazardous and avoid direct contact with skin and eyes. Follow good chemical hygiene practices.

How to store 5-ethyl-2-methylpyridine correctly?

5-ethyl-2-methylpyridine should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers properly labeled and store away from incompatible materials such as strong oxidizing agents and acids. Maintain storage temperature according to supplier specifications and ensure containers are compatible with the chemical to prevent degradation or contamination.

What to do in case of contact with 5-ethyl-2-methylpyridine?

In case of skin contact with 5-ethyl-2-methylpyridine, immediately wash the affected area thoroughly with soap and water for at least 15 minutes. For eye contact, flush immediately with clean water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Remove contaminated clothing and wash before reuse. Seek medical attention if irritation persists or if large amounts were involved in the exposure.

How to dispose of 5-ethyl-2-methylpyridine properly?

5-ethyl-2-methylpyridine should be disposed of according to local and national environmental regulations for organic chemical waste. Do not discharge into drains, waterways, or soil. Collect waste material in appropriate containers for disposal through licensed waste management companies. Consider recycling or recovery options where available. Consult with waste disposal experts to ensure compliance with all applicable environmental protection regulations.

How to transport 5-ethyl-2-methylpyridine?

5-ethyl-2-methylpyridine is classified under ADR as Class 6.1 (Toxic substances) Packing Group III, indicating moderate toxicity requiring specific transport precautions. Use appropriate packaging materials that meet ADR requirements for this classification. Ensure proper labeling and documentation for shipment. Transport vehicles must comply with ADR regulations for Class 6.1 materials, including proper placarding and driver training requirements.

Is 5-ethyl-2-methylpyridine subject to specific regulations?

5-ethyl-2-methylpyridine is subject to standard chemical regulations including REACH registration requirements in Europe for commercial use. It is not classified as a Substance of Very High Concern (SVHC) and has no specific GHS hazard classification. However, it must comply with general chemical safety regulations, workplace exposure limits, and environmental protection requirements applicable to industrial chemicals in each jurisdiction where it is used.

Where to buy 5-ethyl-2-methylpyridine in Europe?

5-ethyl-2-methylpyridine is available through OYSI, a specialized European distributor of technical chemicals and intermediates. OYSI provides reliable supply chains for pharmaceutical and chemical industry customers across Europe. Contact OYSI directly to discuss your specific requirements, quantities, and delivery options. Professional chemical distributors like OYSI ensure proper handling, documentation, and regulatory compliance for industrial chemical purchases.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.