(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine is a complex organic nitrogen-containing heterocyclic compound with the molecular formula C14H20N2. This chiral molecule features a fused bicyclic structure combining pyrrole and pyridine rings with a benzyl substituent. With a molecular weight of 216.32 g/mol and CAS number 151213-39-7, it belongs to the class of octahydropyrrolopyridines and exhibits significant biological activity potential due to its stereochemistry and structural complexity.

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine is an organic solid with a molecular weight of 216.32 g/mol and molecular formula C14H20N2. As a bicyclic amine compound, it likely exhibits basic properties due to its nitrogen atoms. The compound's physical appearance, exact melting point, and solubility characteristics would depend on its specific crystalline form and purity grade, though typical organic amines show varying solubility in polar and non-polar solvents.

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine is primarily used as a pharmaceutical intermediate and research chemical in medicinal chemistry applications. Its complex bicyclic structure with defined stereochemistry makes it valuable for synthesizing bioactive compounds and drug candidates. The compound serves as a building block in organic synthesis, particularly for developing molecules targeting neurological pathways or as chiral auxiliaries in asymmetric synthesis processes within pharmaceutical and fine chemical industries.

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine requires careful handling due to its corrosive properties and toxicity classification. Essential protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work in well-ventilated areas or under fume hoods to avoid inhalation. Given its Acute Tox. 4 and Skin Corr. 1B classifications, minimize exposure time and ensure emergency shower and eyewash stations are readily accessible during handling operations.

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. As a corrosive substance, use chemically resistant containers and provide secondary containment. Store separately from acids, oxidizing agents, and reactive metals. Maintain controlled temperature conditions to preserve stability and prevent decomposition. Ensure storage areas are equipped with appropriate spill containment measures and restrict access to trained personnel only.

Immediate decontamination is essential for any contact with (4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine due to its corrosive nature. For skin contact, immediately flush with copious amounts of water for at least 15 minutes and remove contaminated clothing. In case of eye contact, rinse thoroughly with water for 15 minutes while holding eyelids open. If inhaled, move to fresh air immediately. Seek immediate medical attention for all exposure routes, especially given the substance's acute toxicity classification.

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine must be disposed of through licensed hazardous waste disposal facilities due to its toxicity and environmental classification. The substance requires special handling as hazardous waste under European regulations given its Aquatic Chronic 2 classification. Never discharge into drains, soil, or waterways. Collect waste in appropriate containers, label clearly with substance identification and hazard information, and arrange collection by certified waste management companies following local and national hazardous waste regulations.

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine is classified as ADR Class 8 (corrosive substances), Packing Group II, indicating moderate danger level for transport. Packaging must comply with UN specifications for corrosive materials, using appropriate containers that resist chemical attack. Vehicles must display proper hazard placards and carry emergency response information. Drivers require ADR certification for transporting dangerous goods. Ensure packages are properly labeled with hazard diamonds and comply with quantity limitations for different transport categories.

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine is regulated under European REACH and CLP regulations but is not currently classified as a Substance of Very High Concern (SVHC). The substance must comply with classification, labeling, and packaging requirements due to its hazard profile including acute toxicity and corrosive properties. Users must maintain safety data sheets, implement appropriate risk management measures, and may need to register depending on annual tonnage. Additional national restrictions may apply in specific EU member states.

(4aS,7aS)-6-benzyl-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridine is available through OYSI, a specialized European distributor of technical chemical products. OYSI provides this research-grade chemical compound with proper documentation including safety data sheets and certificates of analysis. As a professional chemical supplier, OYSI ensures compliance with European regulations and proper packaging for safe delivery. Contact OYSI directly for availability, specifications, and technical support for this specialized pharmaceutical intermediate and research chemical compound.