2-[(Z)-2-bromo-2-nitroethenyl]furan

C6H4BrNO3

CAS35950-52-8
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS05 Gefahrensymbol: Ätzend – Ätzwirkung
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

Consulting for 2-[(Z)-2-bromo-2-nitroethenyl]furan

Our experts support you with application, dosage, and compliance.

Request Consultation

Identification

CAS Number
35950-52-8
EC Number
406-110-9
UN Number
3261
Index Number
610-010-00-2
PubChem CID
14993941

Physical-chemical properties

Molecular Formula
C6H4BrNO3
Molar Mass
218.00 g/mol
IUPAC Name
2-[(Z)-2-bromo-2-nitroethenyl]furan

Chemical Identifiers

InChI
InChI=1S/C6H4BrNO3/c7-6(8(9)10)4-5-2-1-3-11-5/h1-4H/b6-4+
InChI Key
MWBCFEHXWNHTDU-GQCTYLIASA-N

Overview

2-[(Z)-2-bromo-2-nitroethenyl]furan (CAS 35950-52-8) is an organobromine nitro compound with corrosive properties and significant biological activity. This specialized chemical compound represents a unique combination of functional groups, featuring a furan ring system coupled with a substituted vinyl moiety containing both bromine and nitro substituents in the Z-configuration. With a molecular formula of C6H4BrNO3 and molecular weight of 218 g/mol, this substance exhibits distinctive reactivity patterns characteristic of halogenated nitroalkenes. The presence of the electron-withdrawing nitro group and the halogen substituent creates a highly electrophilic system, making it valuable for various synthetic applications in organic chemistry. The compound's safety profile requires careful handling protocols due to its classification under multiple hazard categories. It exhibits acute toxicity (Category 4), skin corrosion properties (Category 1B), and potential for causing skin sensitization. Additionally, it presents specific target organ toxicity concerns with repeated exposure (Category 2) and demonstrates significant aquatic toxicity for both acute and chronic exposure scenarios. These characteristics necessitate appropriate personal protective equipment and environmental containment measures during handling and storage. Industrial applications primarily focus on its utility as a synthetic intermediate in pharmaceutical chemistry and agrochemical development, where its unique reactivity profile enables the construction of complex molecular architectures. The compound also finds application in materials science research, particularly in the development of specialized polymers and advanced materials. While structurally distinct from compounds like tributyl(tetradecyl)phosphanium tetrafluoroborate, both substances serve important roles in specialized chemical synthesis applications. OYSI maintains availability of this technical-grade compound for qualified industrial and research applications across European markets.

Safety & Classification

Danger
Classification:

Acute Tox. 4 *; STOT RE 2 *; Skin Corr. 1B; Skin Sens. 1; Aquatic Acute 1; Aquatic Chronic 1

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H302

Harmful if swallowed.

H373

May cause damage to organs through prolonged or repeated exposure.

H314

Causes severe skin burns and eye damage.

H317

May cause an allergic skin reaction.

H400

Very toxic to aquatic life.

H410

Very toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Skin Contact

Harmful

Measures if substance contacts the skin

First Aid Actions

  • +P302IF ON SKIN:
  • +P352Wash with plenty of water.
  • +P361Take off immediately all contaminated clothing.
  • +P313Get medical advice/attention.

Related hazard statements:

Eye Contact

Harmful

Measures if substance gets into the eyes

First Aid Actions

  • +P305IF IN EYES:
  • +P351Rinse cautiously with water for several minutes.
  • +P338Remove contact lenses, if present and easy to do. Continue rinsing.
  • +P313Get medical advice/attention.

Related hazard statements:

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3261
ADR Class8
Packing GroupII
Tunnel CodeE
Proper Shipping Name2-Brom-1-(2-furyl)-2-nitroethylen
Marine PollutantNo

Frequently Asked Questions

What is 2-[(Z)-2-bromo-2-nitroethenyl]furan?

2-[(Z)-2-bromo-2-nitroethenyl]furan is an organohalogen compound with the molecular formula C6H4BrNO3 and CAS number 35950-52-8. This chemical features a furan ring substituted with a bromo-nitroethenyl group in the Z-configuration. With a molecular weight of 218 g/mol, it is classified as a hazardous substance requiring careful handling due to its corrosive, toxic, and sensitizing properties.

What are the physicochemical properties of 2-[(Z)-2-bromo-2-nitroethenyl]furan?

2-[(Z)-2-bromo-2-nitroethenyl]furan is an organic compound containing bromine and nitro functional groups attached to a furan ring system. The presence of these electron-withdrawing groups significantly influences its chemical reactivity and stability. Its molecular structure with the Z-configuration indicates specific stereochemical properties that affect its physical characteristics and biological activity.

What is 2-[(Z)-2-bromo-2-nitroethenyl]furan used for?

2-[(Z)-2-bromo-2-nitroethenyl]furan is primarily used as an intermediate in organic synthesis and pharmaceutical research. Its unique structure containing both bromo and nitro functionalities makes it valuable for developing bioactive compounds and specialty chemicals. The compound serves as a building block in medicinal chemistry for creating molecules with specific biological activities.

How to handle 2-[(Z)-2-bromo-2-nitroethenyl]furan safely?

2-[(Z)-2-bromo-2-nitroethenyl]furan requires strict safety measures due to its corrosive and toxic nature. Essential protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work must be conducted in well-ventilated areas or under fume hoods to prevent inhalation. Avoid skin and eye contact, and ensure emergency shower and eyewash stations are accessible.

How to store 2-[(Z)-2-bromo-2-nitroethenyl]furan correctly?

2-[(Z)-2-bromo-2-nitroethenyl]furan must be stored in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers tightly sealed and store in secondary containment to prevent leaks. Due to its corrosive properties, use chemically resistant storage containers and maintain separation from bases, reducing agents, and organic materials that could react violently.

What to do in case of contact with 2-[(Z)-2-bromo-2-nitroethenyl]furan?

Immediate action is required if contact occurs with 2-[(Z)-2-bromo-2-nitroethenyl]furan. For skin contact, remove contaminated clothing immediately and flush the affected area with copious amounts of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move the person to fresh air and provide respiratory support if needed.

How to dispose of 2-[(Z)-2-bromo-2-nitroethenyl]furan properly?

2-[(Z)-2-bromo-2-nitroethenyl]furan waste must be disposed of according to local and national hazardous waste regulations. The compound cannot be discharged into sewers or the environment due to its aquatic toxicity and corrosive nature. Contact licensed hazardous waste disposal companies for proper treatment and disposal. Maintain detailed waste tracking documentation as required by regulations.

How to transport 2-[(Z)-2-bromo-2-nitroethenyl]furan?

2-[(Z)-2-bromo-2-nitroethenyl]furan is classified under ADR Class 8 (corrosive substances), Packing Group II, indicating medium danger level. Transportation requires appropriate corrosive-resistant packaging and proper hazard labeling. Vehicles must carry emergency response information and drivers need hazardous goods training. Ensure compliance with international dangerous goods regulations for road, air, or sea transport.

Is 2-[(Z)-2-bromo-2-nitroethenyl]furan subject to specific regulations?

2-[(Z)-2-bromo-2-nitroethenyl]furan is subject to various chemical regulations including REACH registration requirements in Europe and CLP classification for hazard communication. While not currently listed as an SVHC substance, its acute toxicity and environmental hazard classifications require compliance with workplace safety standards, environmental protection laws, and proper hazard communication through safety data sheets.

Where to buy 2-[(Z)-2-bromo-2-nitroethenyl]furan in Europe?

2-[(Z)-2-bromo-2-nitroethenyl]furan is available through OYSI, a specialized European distributor of technical chemicals. OYSI provides this compound with complete regulatory documentation, including safety data sheets and certificates of analysis. As a professional chemical supplier, OYSI ensures proper packaging, labeling, and transportation compliance for hazardous substances throughout Europe.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.