4-tert-butylbenzoic acid

4-tert-butylbenzoic acid is an aromatic carboxylic acid with the molecular formula C11H14O2 and CAS number 98-73-7. This organic compound features a benzoic acid structure with a tert-butyl group attached at the para position. With a molecular weight of 178.23 g/mol, it is classified as a hazardous substance with reproductive toxicity, acute toxicity, and specific target organ toxicity properties.

4-tert-butylbenzoic acid is typically a white to off-white crystalline solid at room temperature. As an aromatic carboxylic acid, it exhibits limited solubility in water but dissolves readily in organic solvents such as alcohols, ethers, and aromatic hydrocarbons. The compound has a characteristic aromatic odor and demonstrates typical carboxylic acid properties including acidity and the ability to form salts with bases.

4-tert-butylbenzoic acid is primarily used as an intermediate in organic synthesis and pharmaceutical manufacturing. It serves as a building block for producing various chemical compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. The compound is also utilized in research and development applications, particularly in medicinal chemistry and materials science. Its unique structure makes it valuable for creating derivatives with specific biological or chemical properties.

4-tert-butylbenzoic acid must be handled with extreme caution due to its reproductive toxicity (Repr. 1B) and acute toxicity classifications. Essential personal protective equipment includes chemical-resistant gloves, safety goggles, and protective clothing. Work should be conducted in well-ventilated areas or under fume hoods. Avoid inhalation, skin contact, and ingestion. Pregnant women should not handle this substance. Emergency shower and eyewash stations should be readily accessible.

4-tert-butylbenzoic acid should be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Keep containers away from strong bases, oxidizing agents, and reducing agents. Storage areas should be equipped with appropriate containment measures and restricted to authorized personnel only. Maintain storage temperatures as recommended by the supplier and ensure proper labeling with hazard information.

Immediate action is required upon contact with 4-tert-butylbenzoic acid. For skin contact, remove contaminated clothing and rinse thoroughly with water for at least 15 minutes. If inhaled, move to fresh air immediately. For eye contact, flush with clean water for 15 minutes while holding eyelids open. If ingested, do not induce vomiting and seek immediate medical attention. Always consult a physician after any exposure incident.

4-tert-butylbenzoic acid waste must be disposed of through licensed hazardous waste disposal companies in accordance with local, national, and EU regulations. The substance cannot be disposed of in regular waste streams due to its hazardous classification. Container disposal should follow the same protocols as the chemical itself. Maintain proper documentation of disposal activities and ensure compliance with REACH and waste framework directive requirements.

4-tert-butylbenzoic acid is classified as ADR Class 9 (Miscellaneous dangerous substances), Packing Group III for transportation purposes. This classification requires specific packaging, labeling, and documentation requirements for road transport. Shipments must comply with dangerous goods regulations, including proper packaging instructions, hazard labels, and transport documentation. Only authorized carriers experienced in hazardous materials transport should handle shipments.

4-tert-butylbenzoic acid is subject to comprehensive EU chemical regulations including REACH registration requirements and CLP classification and labeling obligations. The substance's reproductive toxicity classification (Repr. 1B) subjects it to authorization and restriction considerations under REACH. Safety data sheets must be provided to professional users, and workplace exposure limits may apply. Regular review of regulatory status is essential as requirements may evolve.

4-tert-butylbenzoic acid is available through OYSI, a specialized European distributor of technical chemicals. As professional chemical suppliers, OYSI can provide this regulated substance to qualified industrial and research customers with proper documentation and safety data sheets. Purchase requires verification of legitimate industrial or research use due to the substance's hazardous classification and regulatory requirements under European chemical legislation.