4-nitrosophenol

4-nitrosophenol is an organic chemical compound with the molecular formula C6H5NO2 and CAS number 104-91-6. It belongs to the family of nitrosophenols, featuring a phenol ring with a nitroso group (-NO) attached at the para position. This compound has a molecular weight of 123.11 g/mol and is classified as a hazardous substance with mutagenic properties and acute toxicity potential.

4-nitrosophenol is typically a solid crystalline compound at room temperature with a characteristic yellow to brown coloration. The nitroso group gives it distinctive chemical reactivity, making it sensitive to light and heat. It exhibits moderate solubility in organic solvents and limited water solubility. The compound is prone to decomposition under certain conditions and may undergo tautomeric equilibrium with its quinone oxime form.

4-nitrosophenol serves primarily as a chemical intermediate in organic synthesis and pharmaceutical research. It is used in the production of dyes, pigments, and other aromatic compounds. The compound also finds application in analytical chemistry as a reagent for certain detection methods. Additionally, it may be utilized in research laboratories for studying nitrosation reactions and as a precursor for synthesizing more complex organic molecules.

4-nitrosophenol requires careful handling due to its mutagenic properties and acute toxicity. Personal protective equipment including chemical-resistant gloves, safety goggles, and laboratory coats must be worn. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation exposure. Avoid skin and eye contact, and prevent dust formation during handling. Regular safety training and adherence to laboratory safety protocols are essential when working with this substance.

4-nitrosophenol should be stored in a cool, dry, well-ventilated area away from direct sunlight and heat sources. The compound must be kept in tightly sealed, chemically compatible containers to prevent moisture absorption and contamination. Storage areas should be equipped with appropriate containment measures and restricted access. Keep away from incompatible materials such as strong oxidizers and bases. Regular inspection of storage containers is recommended to ensure integrity.

4-nitrosophenol contact requires immediate action due to its hazardous properties. In case of skin contact, immediately remove contaminated clothing and rinse the affected area with copious amounts of water for at least 15 minutes. For eye contact, flush eyes thoroughly with clean water and seek immediate medical attention due to potential eye damage. If inhaled, move the person to fresh air immediately. Contact emergency services and poison control centers as necessary.

4-nitrosophenol disposal must comply with local and international hazardous waste regulations due to its toxic and mutagenic properties. The compound cannot be disposed of through regular waste streams and requires specialized hazardous waste treatment. Contact licensed waste disposal companies experienced in handling toxic organic compounds. Incineration at high temperatures in approved facilities is typically the recommended disposal method. Maintain proper documentation and disposal records as required by regulations.

4-nitrosophenol is classified under ADR Class 4.1 as a flammable solid, requiring specific transportation protocols. Packages must be properly labeled with appropriate hazard symbols and shipping documentation. Transport vehicles should be equipped with suitable containment measures and emergency equipment. Drivers must have proper training for hazardous materials transport. Compliance with international shipping regulations including proper packaging, marking, and documentation is mandatory for safe transport.

4-nitrosophenol is subject to various regulatory frameworks including REACH registration requirements in Europe and CLP classification regulations. The compound is classified with multiple hazard categories including mutagenicity category 2, requiring specific labeling and safety data sheets. While not currently listed as an SVHC substance, its mutagenic properties place it under strict regulatory oversight. Users must comply with occupational exposure limits and workplace safety regulations when handling this substance.

4-nitrosophenol is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI provides this compound to qualified industrial and research customers across Europe. Due to the hazardous nature of 4-nitrosophenol, purchases typically require proper documentation, safety credentials, and compliance with regulatory requirements. Contact OYSI directly for availability, technical specifications, and regulatory compliance support for your specific application needs.