2-bromo-2-nitropropane-1,3-diol

2-bromo-2-nitropropane-1,3-diol is an antimicrobial compound with the molecular formula C3H6BrNO4 and CAS number 52-51-7. This chemical substance has a molecular weight of 199.99 g/mol and contains both bromine and nitro functional groups attached to a propane backbone with two hydroxyl groups. It is classified as a hazardous substance with multiple danger classifications including acute toxicity, skin irritation, and eye damage potential.

2-bromo-2-nitropropane-1,3-diol is a crystalline solid at room temperature with good water solubility due to its hydroxyl groups. The compound appears as white to off-white crystals and is stable under normal storage conditions. Its molecular structure combines hydrophilic hydroxyl groups with halogenated and nitro functionalities, making it effective as a preservative while maintaining reasonable water solubility for various applications.

2-bromo-2-nitropropane-1,3-diol is primarily used as a broad-spectrum antimicrobial preservative in cosmetic and personal care products. It effectively inhibits the growth of bacteria, yeasts, and molds in water-based formulations such as shampoos, conditioners, and skin care products. The compound is particularly valued for its stability and effectiveness at low concentrations, making it suitable for pH-sensitive formulations where other preservatives may be less effective.

2-bromo-2-nitropropane-1,3-diol requires careful handling with appropriate personal protective equipment including safety goggles, chemical-resistant gloves, and protective clothing. Work should be conducted in well-ventilated areas or under fume extraction systems. Avoid direct skin and eye contact, and prevent inhalation of dust particles. The substance is classified as Acute Tox. 4, Skin Irrit. 2, and Eye Dam. 1, requiring strict adherence to safety protocols during use.

2-bromo-2-nitropropane-1,3-diol should be stored in a cool, dry, well-ventilated area away from heat sources and direct sunlight. Keep containers tightly closed and store in original packaging. Avoid storage near strong reducing agents, alkalis, and combustible materials. The storage area should be equipped with appropriate spill containment measures and maintained at stable temperatures to prevent degradation of the compound.

2-bromo-2-nitropropane-1,3-diol contact requires immediate action: for skin contact, wash thoroughly with soap and water for at least 15 minutes. For eye contact, rinse immediately with clean water for at least 15 minutes and seek medical attention due to the Eye Dam. 1 classification. If inhaled, move to fresh air immediately. Remove contaminated clothing and wash before reuse. Seek medical attention if irritation persists or if significant exposure has occurred.

2-bromo-2-nitropropane-1,3-diol must be disposed of according to local and national hazardous waste regulations. The compound cannot be disposed of with regular waste due to its hazard classifications and environmental impact (Aquatic Acute 1). Contact licensed hazardous waste disposal companies for proper collection and treatment. Empty containers should also be handled as hazardous waste and never be reused for other purposes without proper decontamination procedures.

2-bromo-2-nitropropane-1,3-diol is classified under ADR as Class 4.1 (Flammable solids), Packing Group III for transportation purposes. Packages must comply with UN packaging requirements and be properly labeled with hazard pictogrammes and transport documentation. Vehicles must carry appropriate safety equipment and emergency response information. Only qualified personnel should handle transportation, ensuring compliance with international dangerous goods regulations and proper segregation from incompatible materials.

2-bromo-2-nitropropane-1,3-diol is subject to REACH regulation requiring registration for import/manufacture above 1 tonne annually. It is not currently listed as an SVHC substance but must comply with CLP regulation for classification and labeling. The substance requires safety data sheets and appropriate hazard communication. Additionally, its use in cosmetic products is regulated under the EU Cosmetic Regulation, with specific concentration limits and usage restrictions that must be observed.

2-bromo-2-nitropropane-1,3-diol is available through OYSI, a specialized European distributor of technical chemicals and industrial raw materials. OYSI provides this preservative to professional users across Europe with proper documentation, safety data sheets, and regulatory compliance support. As a restricted chemical requiring careful handling and regulatory compliance, it is only supplied to qualified industrial users and cosmetic manufacturers with appropriate facilities and expertise.