2-chloro-6-fluorophenol

2-chloro-6-fluorophenol is an organofluorine compound with the molecular formula C6H4ClFO and CAS number 2040-90-6. This halogenated phenol derivative contains both chlorine and fluorine substituents on a benzene ring with a hydroxyl group. With a molecular weight of 146.54 g/mol, it is classified as a hazardous chemical requiring careful handling due to its multiple danger classifications including mutagenic, reproductive toxic, and skin corrosive properties.

2-chloro-6-fluorophenol is a solid organic compound at room temperature with a molecular weight of 146.54 g/mol. As a halogenated phenol, it typically appears as a crystalline solid with characteristic aromatic properties. The presence of both electron-withdrawing halogen substituents (chlorine and fluorine) affects its acidity and solubility profile. Specific physical parameters such as melting point, boiling point, and solubility data should be consulted from technical datasheets for precise applications.

2-chloro-6-fluorophenol serves as an important intermediate in pharmaceutical and agrochemical synthesis. Its unique substitution pattern makes it valuable for manufacturing various organic compounds where both chlorine and fluorine functionalities are required. The compound is commonly used in research and development applications, particularly in medicinal chemistry for developing new drug molecules. It may also find applications in specialty chemical manufacturing and as a building block for more complex fluorinated compounds.

2-chloro-6-fluorophenol requires strict safety measures due to its corrosive and toxic properties. Essential PPE includes chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact. Work should be conducted in well-ventilated areas or under fume hoods to avoid inhalation. Given its skin corrosive (1B) and sensitizing properties, direct contact must be avoided. Emergency eyewash stations and safety showers should be readily accessible when handling this substance.

2-chloro-6-fluorophenol should be stored in tightly sealed containers in a cool, dry, and well-ventilated area away from heat sources and incompatible materials. As a corrosive substance (ADR Class 8), it requires appropriate containment to prevent leakage. Storage areas should be equipped with spill containment measures and restricted to authorized personnel only. The compound should be kept away from strong bases, oxidizing agents, and reactive metals to prevent dangerous reactions.

Immediate action is required upon contact with 2-chloro-6-fluorophenol due to its corrosive nature. For skin contact, immediately remove contaminated clothing and flush affected areas with plenty of water for at least 15 minutes. In case of eye contact, rinse thoroughly with water and seek immediate medical attention. If inhaled, move to fresh air immediately. For ingestion, do not induce vomiting and seek emergency medical care. Always consult the safety data sheet for complete first aid procedures.

2-chloro-6-fluorophenol must be disposed of as hazardous waste according to local and national regulations. The compound cannot be discharged into sewers or waterways due to its environmental hazard classification (Aquatic Chronic 2). Disposal should be carried out by licensed waste management companies specialized in handling toxic and corrosive chemicals. Incineration at appropriate temperatures in authorized facilities is typically the preferred method. Always consult local environmental authorities for specific disposal requirements.

2-chloro-6-fluorophenol is classified as ADR Class 8 (corrosive substances), Packing Group II, requiring specific transport procedures. Packages must be properly labeled with appropriate hazard pictogrammes and transport documentation must accompany shipments. Vehicles transporting this substance need proper placarding and drivers require ADR certification. Packaging must meet UN specification requirements for corrosive materials and ensure no leakage during transport. Professional logistics companies experienced with dangerous goods should handle transportation.

2-chloro-6-fluorophenol is subject to various European chemical regulations including REACH registration requirements and CLP classification obligations. It is not currently listed as a Substance of Very High Concern (SVHC), but its hazard profile requires compliance with occupational health and safety regulations. Users must ensure proper risk assessments, safety data sheet distribution, and worker training. Import/export may require additional permits depending on destination countries and quantities involved.

2-chloro-6-fluorophenol is available through OYSI, a specialized European distributor of technical chemicals. As an established chemical supplier, OYSI provides this compound with proper documentation, safety data sheets, and regulatory compliance support. Professional chemical distributors like OYSI ensure product quality, appropriate packaging, and adherence to transport regulations. Contact OYSI directly for availability, specifications, and technical support for your specific application requirements in pharmaceutical or chemical synthesis projects.