4-methoxybenzene-1,3-diamine

C7H10N2O

CAS615-05-4
GHS08 Gefahrensymbol: Gesundheitsgefahr – Gesundheitsgefahr
GHS07 Gefahrensymbol: Gesundheitsschädlich/Reizend – Ausrufezeichen
GHS09 Gefahrensymbol: Umweltgefährlich – Umwelt
Danger

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Identification

CAS Number
615-05-4
EC Number
210-406-1
UN Number
3077
Index Number
612-200-00-0
PubChem CID
11976

Physical-chemical properties

Molecular Formula
C7H10N2O
Molar Mass
138.17 g/mol
IUPAC Name
4-methoxybenzene-1,3-diamine

Chemical Identifiers

InChI
InChI=1S/C7H10N2O/c1-10-7-3-2-5(8)4-6(7)9/h2-4H,8-9H2,1H3
InChI Key
BAHPQISAXRFLCL-UHFFFAOYSA-N

Overview

4-methoxybenzene-1,3-diamine (CAS 615-05-4) is an aromatic diamine compound with methoxy substitution used in specialized chemical synthesis applications. This organic compound, also identified by EC number 210-406-1, belongs to the family of substituted aromatic diamines with a molecular formula of C7H10N2O and molecular weight of 138.17 g/mol. The compound features a benzene ring substituted with two amino groups at the 1,3-positions and a methoxy group at the 4-position, making it a valuable intermediate in various chemical manufacturing processes. The substance requires careful handling due to its significant hazard profile, classified under multiple danger categories including carcinogenicity (Carc. 1B), mutagenicity (Muta. 2), acute toxicity (Acute Tox. 4), and aquatic chronic toxicity (Aquatic Chronic 2). These classifications mandate the "Danger" signal word and require appropriate GHS pictograms (GHS08, GHS07, GHS09) on packaging. Transportation falls under ADR Class 9, indicating miscellaneous dangerous goods requiring specialized logistics protocols. Industrial applications primarily focus on dye intermediate synthesis, where the compound's dual amino functionality enables complex chromophore development. The pharmaceutical industry utilizes this diamine in active pharmaceutical ingredient synthesis, particularly in compounds requiring specific aromatic substitution patterns. Additionally, it serves as a building block in specialty polymer production. Related compounds in this chemical family include substances like cobalt(2+) sulfate, which may be used in conjunction with aromatic diamines in certain dyeing applications, and diphenyldiazene, another aromatic nitrogen-containing compound used in similar industrial sectors. OYSI maintains availability of 4-methoxybenzene-1,3-diamine through its European distribution network, ensuring compliance with all relevant chemical regulations and safety requirements.

Safety & Classification

Danger
Classification:

Carc. 1B; Muta. 2; Acute Tox. 4 *; Aquatic Chronic 2

HHazard Statements (H-Statements)

Describe the nature and severity of the hazard

H350

May cause cancer.

H341

Suspected of causing genetic defects.

H302

Harmful if swallowed.

H411

Toxic to aquatic life with long lasting effects.

Classification according to CLP Regulation (EC) No 1272/2008. The complete list of hazard and precautionary statements can be found in the Safety Data Sheet (SDS).

First Aid Measures

Ingestion

Harmful

Measures if substance is accidentally swallowed

First Aid Actions

  • +P301IF SWALLOWED:
  • +P330Rinse mouth.
  • +P331Do NOT induce vomiting.
  • +P310Immediately call a POISON CENTER/doctor.

Related hazard statements:

General Measures

Emergency 112 | Poison Control: +49 30 19240 (DE), +33 1 45 42 59 59 (FR), +31 30 274 88 88 (NL)

First aid measures are based on CLP classification and associated P-statements. They do not replace the Safety Data Sheet (SDS). In case of emergency, always consult the full SDS and a physician.

Transport (ADR)

UN Number3077
ADR Class9
Packing GroupIII
Tunnel Code-
Proper Shipping Name2,4-Diaminoanisol
Marine PollutantNo

Frequently Asked Questions

What is 4-methoxybenzene-1,3-diamine?

4-methoxybenzene-1,3-diamine is an aromatic organic compound with the molecular formula C7H10N2O and molecular weight 138.17 g/mol. This chemical features a benzene ring substituted with a methoxy group (-OCH3) at position 4 and two amino groups (-NH2) at positions 1 and 3. It belongs to the diaminoanisole family and is classified as a hazardous substance with carcinogenic and mutagenic properties under CLP regulation.

What are the physicochemical properties of 4-methoxybenzene-1,3-diamine?

4-methoxybenzene-1,3-diamine typically appears as a crystalline solid at room temperature with a characteristic aromatic amine odor. The compound contains both hydrophilic amino groups and a hydrophobic methoxybenzene structure, affecting its solubility properties. Its molecular structure with electron-donating methoxy and amino substituents influences its reactivity and stability. Specific physical parameters should be verified from technical datasheets for precise handling requirements.

What is 4-methoxybenzene-1,3-diamine used for?

4-methoxybenzene-1,3-diamine serves primarily as an intermediate in chemical synthesis and manufacturing processes. It is commonly used in the production of dyes, pigments, and pharmaceutical intermediates due to its reactive amino groups. The compound also finds applications in polymer chemistry and as a building block for specialty chemicals. Its use is restricted in consumer applications due to its hazardous classification as a carcinogen and mutagen.

How to handle 4-methoxybenzene-1,3-diamine safely?

4-methoxybenzene-1,3-diamine requires strict safety precautions due to its carcinogenic and mutagenic properties. Personnel must wear appropriate PPE including nitrile gloves, safety goggles, and respiratory protection in well-ventilated areas or fume hoods. Skin and eye contact must be avoided completely. Work surfaces should be contained and decontaminated after use. Only trained personnel should handle this substance following established safety protocols and risk assessments.

How to store 4-methoxybenzene-1,3-diamine correctly?

4-methoxybenzene-1,3-diamine must be stored in tightly sealed containers in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Storage areas should be restricted to authorized personnel only due to the substance's carcinogenic classification. Containers should be clearly labeled with hazard information and stored according to local chemical storage regulations. Regular inventory checks and proper segregation from oxidizing agents and acids are essential for safe storage.

What to do in case of contact with 4-methoxybenzene-1,3-diamine?

Immediate action is critical following contact with 4-methoxybenzene-1,3-diamine. For skin contact, remove contaminated clothing and wash thoroughly with soap and water for at least 15 minutes. In case of eye contact, flush immediately with clean water for 15-20 minutes. If inhaled, move to fresh air immediately. Seek medical attention promptly in all cases of exposure, informing medical personnel of the substance's carcinogenic properties and providing the safety data sheet.

How to dispose of 4-methoxybenzene-1,3-diamine properly?

4-methoxybenzene-1,3-diamine must be disposed of as hazardous waste through licensed waste management companies specialized in carcinogenic substances. The material cannot be discharged to sewers or general waste streams due to its environmental and health hazards. Disposal must comply with local, national, and EU waste regulations including proper classification, packaging, and documentation. Incineration at appropriate high-temperature facilities is typically the preferred disposal method for this type of hazardous organic compound.

How to transport 4-methoxybenzene-1,3-diamine?

4-methoxybenzene-1,3-diamine is classified as ADR Class 9 (Miscellaneous dangerous goods), Packing Group III for transportation purposes. The substance requires appropriate packaging, labeling, and documentation according to dangerous goods regulations. Transport vehicles must carry proper placarding and emergency response information. Only certified carriers experienced in handling hazardous chemicals should transport this material, ensuring compliance with international transport regulations and proper emergency response capabilities.

Is 4-methoxybenzene-1,3-diamine subject to specific regulations?

4-methoxybenzene-1,3-diamine is subject to strict regulatory oversight under REACH and CLP regulations due to its carcinogenic and mutagenic classification. The substance requires proper registration, classification, labeling, and packaging according to EU chemical legislation. Users must implement appropriate risk management measures and maintain safety data sheets. Some applications may be restricted or require special authorization. Companies handling this material must ensure compliance with occupational exposure limits and workplace safety regulations.

Where to buy 4-methoxybenzene-1,3-diamine in Europe?

4-methoxybenzene-1,3-diamine is available through OYSI, a specialized European distributor of technical chemicals with expertise in hazardous substances. As a professional chemical supplier, OYSI ensures proper handling, packaging, and documentation for regulatory compliance. Due to the substance's hazardous nature, purchases are restricted to qualified industrial users with appropriate safety infrastructure and regulatory permissions. Contact OYSI directly for availability, technical specifications, and regulatory documentation requirements for your specific application.

Data Sources

Classification per CLP Regulation (EC) No 1272/2008. Data from ECHA and PubChem.